MSc Genomic Medicine

A flexible, multi-disciplinary and multi-professional perspective in genomics applied to clinical practice and medical research.

Award titles

MSc

Duration: 1 year FT / 2 years PT
ECTS: 90 ECTS credits
(including PG Cert and PG Dip)

Postgraduate Certificate

Duration: 4 months FT / 1 year PT
ECTS: 30 ECTS credits
(standalone course)

Postgraduate Diploma

Duration: 8 months FT / 2 year PT
ECTS: 60 ECTS credits
(including PG Cert)

Your Autumn term and academic year 2020–21

This course will begin on schedule in the Autumn and we plan to reopen our campuses. We are looking forward to seeing you in person, if travel and visa arrangements allow. If you can’t travel to campus in time for the start of term, we want to reassure you that your academic Department has made plans which make it possible to offer  you  a  high-quality remote educational experience during the Autumn term.

Your teaching will be a combination of on-campus (in-person) and remote learning (online). We call this ‘multi-mode’ delivery. Depending on official government guidance throughout the entirety of next academic year, the ‘multi-mode’ balance may be subject to change. We hope to be able to offer you increased on-campus teaching and learning activities throughout the year.

For more information about multi-mode delivery, your learning experience and the steps we’ll be taking to keep you safe on campus if you are able to join us, please see our COVID-19 information for applicants and offer holders.


Key information

Start dateOctober 2020
Campus: Various
Register your interestApply now

Overview

The Genomic Medicine programme covers all aspects of genomic science and medicine, and will equip you with the knowledge and skills to be able to interpret and understand genomic data that increasingly impacts on service delivery to patients and the community.

The programme is aimed at students from a wide range of backgrounds, from basic scientists to all levels of healthcare professionals, and will provide a flexible, multi-disciplinary and multi-professional perspective in genomics, applied to clinical practice and medical research.

The training provided covers all aspects of genomic science and medicine (not merely DNA sequencing or detection of genetic variation), undertaken in one of the most cutting-edge scientific environments. The programme runs successfully through a combination of educational materials and opportunities to interact online alongside more traditional teaching methods. This blended format of delivery consists of teaching sessions (face-to-face or made available online), live webinars, discussion fora, formative and summative assessments administered through our virtual learning environment, and a range of resources to facilitate self-study and progression. This allows for much of the programme to be studied remotely if required.

Following this degree, many of our students have continued to clinical and non-clinical PhDs, to graduate medical degrees, graduate roles in industry and to the NHS Scientific Training Programme. We also have a large number of part-time students who are keen to develop their application of genomic medicine within their current professional role.

The programme includes collaborations with:

  • the Institute of Cancer Research (providing the core Cancer Genomics Module)
  • Brunel University London (providing the optional Economic Evaluation in Human Genomics Module)

Staff from the Institute of Cancer Research and Brunel University London may also co-supervise research projects.

The programme is one of the preferred providers for Health Education England and upholds the values of the NHS Constitution.

Study programme

This programme is made up of three progressional levels (PG Cert, PG Dip and MSc), and you can apply to any level in the first instance. Read more about how this works under 'Choosing your course' in the how to apply section.

One of the core modules available within the Master's degree (MSc) includes opportunities to access the emerging data from the 100,000 Genomes Project through the Genomics England Clinical Interpretation Partnership (GeCIP) training domains.

Meet our students

Hear from Genomic Medicine students and graduates on the National Heart and Lung Institute website.

Funding

As a preferred training provider for Health Education England, this course plays an important role in ensuring NHS staff have the knowledge, skills and experience required to stay at the forefront of this essential field. We continually make improvements to the course content to ensure that our education continues to respond to the needs of modern healthcare practice.

NHS and Public Health England employees can now apply for a HEE Genomics Education Programme scholarship to cover the tuition fees for individual modules, or longer programmes such as the PG Cert, PG Dip or the Masters. To find out more about this funding and how you can apply please visit the HEE GEP website.

Please note that due to funding restrictions there are limited HEE GEP-funded places available on the October intake. Success in the HEE GEP scholarship application does not guarantee an HEE-funded place at Imperial College London.

Structure

Modules shown are for the current academic year and are subject to change depending on your year of entry.

Please note that the curriculum of this programme is currently being reviewed as part of a College-wide process to introduce a standardised modular structure. As a result, the content and assessment structures of this course may change for your year of entry. We therefore recommend that you check this course page before finalising your application and after submitting it as we will aim to update this page as soon as any changes are ratified by the College.

Find out more about the limited circumstances in which we may need to make changes to or in relation to our courses, the type of changes we may make and how we will tell you about changes we have made.

 

Structure

MSc

Core modules

Fundamentals in Human Genetics and Genomics

Module Leader: Dr Louise Blakemore

Provides the basic genomic science knowledge required in subsequent modules, including genomic architecture, regulatory systems, generic variation, function and how this impacts upon disease processes and clinical outcomes. 

Omics Technologies and their Application to Genomic Medicine

Provides an in–depth description of the genomic techniques that are used to assess genomic variation in clinical problems, allowing you to critically evaluate which techniques can be used and their limitations in analysing different disease states.

Application of Genomics in Infectious Disease

Module Leader: Dr Luke Allsopp

Explains how pathogen genomics inform the epidemiology of infections, impact drug development and resistance, lead to novel diagnostics/therapeutics/stratified healthcare, and provide insights into host susceptibilities to infection. 

Molecular Pathology of Cancer and Application in Cancer Diagnosis, Screening and Treatment

Module Leader: Professor Ros Eeles

Explains the principles of cancer genomics, including predisposition, diagnosis, classification, treatment and patient monitoring with particular emphasis on how genomic analysis impacts these factors and ethical issues. This module is delivered by the Institute of Cancer Research.

Genomics of Common and Rare Inherited Diseases

Explains the different types of genetic variation, their contribution to rare and complex disease, and how they are detected (with emphasis on the 100,000 Genomes Project), interpreted and communicated.

Bioinformatics, Quality Control, Analysis and Interpretation of Sequencing Data

Module Leader: Professor Michael Lovett

Provides the principles of computational DNA sequence analysis, including sequence alignment methods and statistical tests, to identify and correctly communicate pathogenic mutations and assess possible functions through database and network programs. 

Optional modules

Group 1

You choose one optional module from the list below.

Ethical, Legal and Social Issues in Applied Genomics

Module Leader: Professor Geraldine Thomas

Explains the principles and subtleties of ethics in evaluating genetic/genomic data with an emphasis on emerging genomics technologies and the ways ethics issues are handled around the world. 

Genomics and the Patient

Module Leader: Dr Claire Shovlin

Concentrates on the identification and interpretation of final Next–Generation DNA sequencing reports with an emphasis on calculating genetic risk and ethical considerations (less computationally intense). 

Group 2

You choose one optional module from the list below.

Pharmacogenomics and Stratified Medicine

Module Leader: Dr Letizia Foroni

Explains how genomic approaches can be used to understand the mechanisms of differential drug responses and reactions, and to inform patient stratification. An emphasis will be placed upon the current limitations and future prospects of pharmacogenomic studies. 

Economic Evaluation in Human Genomics

Module Leader: Dr Subhash Pokhrel

Explains the methods, assumptions, decision models, and interpretation of, cost estimate analysis, for health care interventions and health outcomes, with a particular emphasis on genomic medicine. This module is delivered by Brunel University London. 

Genome-Based Therapeutics

Module leaders: Dr Charlotte Dean and Dr Jack Hickmott

Covers key concepts in developing gene and nucleic acid-based therapies from genomic studies including efficacy and toxicity. 

Professional and Research Skills

An e-learning module. Teaches the differences between audit, research, qualitative, quantitative and systematic review methods, how to conduct literature searches, appraise published data, conduct appropriate statistical tests and understand the data management, ethical and reporting requirements in research studies, with a particular emphasis on the 100,000 Genomes Project and translational research.

Research project

You will complete a 14 week-full time or one-year part-time research project as part of the MSc. We offer four types of project:

  • laboratory-based
  • clinically-based
  • computer-based
  • literature-based

Assessment is by written dissertation and an oral presentation.

Research projects may be supervised at Imperial, or co-supervised at Imperial and the Institute of Cancer Research or Brunel University London.

Postgraduate Certificate

Core module

Fundamentals in Human Genetics and Genomics

Module Leader: Dr Louise Blakemore

Provides the basic genomic science knowledge required in later modules, including genomic architecture, regulatory systems, generic variation, function and how this impacts upon disease processes and clinical outcomes. 

Optional modules

You choose three optional modules in total.

Group 1

You choose between one and three optional modules from the list below.

Omics Technologies and their Application to Genomic Medicine

Provides an in–depth description of the genomic techniques that are used to assess genomic variation in clinical problems, allowing you to critically evaluate which techniques can be used and their limitations in analysing different disease states.

Application of Genomics in Infectious Disease

Module Leader: Dr Luke Allsopp

Explains how pathogen genomics inform the epidemiology of infections, impact drug development and resistance, lead to novel diagnostics/therapeutics/stratified healthcare, and provide insights into host susceptibilities to infection.

Molecular Pathology of Cancer and Application in Cancer Diagnosis, Screening and Treatment

Module Leader: Professor Ros Eeles

Explains the principles of cancer genomics, including predisposition, diagnosis, classification, treatment and patient monitoring with particular emphasis on how genomic analysis impacts these factors and ethical issues. This module is delivered by the Institute of Cancer Research.

Genomics of Common and Rare Inherited Diseases

Explains the different types of genetic variation, their contribution to rare and complex disease, and how they are detected (with emphasis on the 100,000 Genomes Project), interpreted and communicated.

Bioinformatics, Quality Control, Analysis and Interpretation of Sequencing Data

Module Leader: Professor Michael Lovett

Provides the principles of computational DNA sequence analysis, including sequence alignment methods and statistical tests, to identify and correctly communicate pathogenic mutations and assess possible functions through database and network programs. 

Group 2

You can choose up to one optional module from the list below.

Ethical, Legal and Social Issues in Applied Genomics

Module Leader: Professor Geraldine Thomas

Explains the principles and subtleties of ethics in evaluating genetic/genomic data with an emphasis on emerging genomics technologies and the ways ethics issues are handled around the world. 

Genomics and the Patient

Module Leader: Dr Claire Shovlin

Concentrates on the identification and interpretation of final Next–Generation DNA sequencing reports with an emphasis on calculating genetic risk and ethical considerations (less computationally intense). 

Group 3

You can choose up to one optional module from the list below.

Pharmacogenomics and Stratified Medicine

Module Leader: Dr Letizia Foroni

Explains how genomic approaches can be used to understand the mechanisms of differential drug responses and reactions, and to inform patient stratification. An emphasis will be placed upon the current limitations and future prospects of pharmacogenomic studies. 

Economic Evaluation in Human Genomics

Module Leader: Dr Subhash Pokhrel

Explains the methods, assumptions, decision models, and interpretation of, cost estimate analysis, for health care interventions and health outcomes, with a particular emphasis on genomic medicine. This module is delivered by Brunel University London. 

Genome-Based Therapeutics

Module leaders: Dr Charlotte Dean and Dr Jack Hickmott

Covers key concepts in developing gene and nucleic acid-based therapies from genomic studies including efficacy and toxicity. 

Professional and Research Skills

An e-learning module. Teaches the differences between audit, research, qualitative, quantitative and systematic review methods, how to conduct literature searches, appraise published data, conduct appropriate statistical tests and understand the data management, ethical and reporting requirements in research studies, with a particular emphasis on the 100,000 Genomes Project and translational research.

Postgraduate Diploma

Core modules

Fundamentals in Human Genetics and Genomics

Module Leader: Dr Louise Blakemore

Provides the basic genomic science knowledge required in later modules, including genomic architecture, regulatory systems, generic variation, function and how this impacts upon disease processes and clinical outcomes. 

Omics Technologies and their Application to Genomic Medicine

Provides an in–depth description of the genomic techniques that are used to assess genomic variation in clinical problems, allowing you to critically evaluate which techniques can be used and their limitations in analysing different disease states.

Application of Genomics in Infectious Disease

Module Leader: Dr Luke Allsopp

Explains how pathogen genomics inform the epidemiology of infections, impact drug development and resistance, lead to novel diagnostics/therapeutics/stratified healthcare, and provide insights into host susceptibilities to infection.

Molecular Pathology of Cancer and Application in Cancer Diagnosis, Screening and Treatment

Module Leader: Professor Ros Eeles

Explains the principles of cancer genomics, including predisposition, diagnosis, classification, treatment and patient monitoring with particular emphasis on how genomic analysis impacts these factors and ethical issues. This module is delivered by the Institute of Cancer Research.

Genomics of Common and Rare Inherited Diseases

Explains the different types of genetic variation, their contribution to rare and complex disease, and how they are detected (with emphasis on the 100,000 Genomes Project), interpreted and communicated.

Bioinformatics, Quality Control, Analysis and Interpretation of Sequencing Data

Module Leader: Professor Michael Lovett

Provides the principles of computational DNA sequence analysis, including sequence alignment methods and statistical tests, to identify and correctly communicate pathogenic mutations and assess possible functions through database and network programs. 

Optional modules

Group 1

You choose one optional module from the list below.

Ethical, Legal and Social Issues in Applied Genomics

Module Leader: Professor Geraldine Thomas

Explains the principles and subtleties of ethics in evaluating genetic/genomic data with an emphasis on emerging genomics technologies and the ways ethics issues are handled around the world. 

Genomics and the Patient

Module Leader: Dr Claire Shovlin

Concentrates on the identification and interpretation of final Next–Generation DNA sequencing reports with an emphasis on calculating genetic risk and ethical considerations (less computationally intense). 

Group 2

You choose one optional module from below.

Pharmacogenomics and Stratified Medicine

Module Leader: Dr Letizia Foroni

Explains how genomic approaches can be used to understand the mechanisms of differential drug responses and reactions, and to inform patient stratification. An emphasis will be placed upon the current limitations and future prospects of pharmacogenomic studies. 

Economic Evaluation in Human Genomics

Module Leader: Dr Subhash Pokhrel

Explains the methods, assumptions, decision models, and interpretation of, cost estimate analysis, for health care interventions and health outcomes, with a particular emphasis on genomic medicine. This module is delivered by Brunel University London.

Genome-Based Therapeutics

Module leaders: Dr Charlotte Dean and Dr Jack Hickmott

Covers key concepts in developing gene and nucleic acid-based therapies from genomic studies including efficacy and toxicity. 

Professional and Research Skills

An e-learning module. Teaches the differences between audit, research, qualitative, quantitative and systematic review methods, how to conduct literature searches, appraise published data, conduct appropriate statistical tests and understand the data management, ethical and reporting requirements in research studies, with a particular emphasis on the 100,000 Genomes Project and translational research.

Teaching and assessment

Teaching methods

  • Computer lab teaching
  • Data analysis sessions
  • Debates
  • Discussion sessions
  • Interactive content including video and module quizzes
  • Journal clubs
  • Keynote lectures
  • Laboratory teaching
  • Lectures
  • On-line discussion forums
  • On-line lecture materials
  • Problem-based group work
  • Seminars

Assessment methods

  • Coursework
  • Practical
  • Research project (MSc only)

Course timetable

A blended approach to learning is used, in both core and optional modules, combining face-to-face teaching and online distance learning. This is to provide flexibility for health professionals to combine their study with work.

Most modules will consist of one week of face-to-face teaching and up to three weeks of e-learning and independent study. The modules are offered on a cycle of 12 months, so that all modules become available once in each 12 month cycle.

The course is flexible and modular and is available as a full-time or part-time MSc delivered over one or two years respectively. There are also full-time and part-time Postgraduate Certificate (PG Cert) and Postgraduate Diploma (PG Dip) options.

Entry requirements

We welcome students from all over the world and consider all applicants on an individual basis.

Admissions

Minimum academic requirement

Our minimum requirement is a 2.1 degree in a relevant medical, biomedical or healthcare subject.

In special cases students may be admitted to this course with high-quality work experience in place of the above requirement.

International qualifications

We also accept a wide variety of international qualifications.

The academic requirement above is for applicants who hold or who are working towards a UK qualification.

For guidance see our Country Index though please note that the standards listed here are the minimum for entry to the College, and not specifically this Department.

If you have any questions about admissions and the standard required for the qualification you hold or are currently studying then please contact the relevant admissions team.

English language requirement (all applicants)

All candidates must demonstrate a minimum level of English language proficiency for admission to the College.

For admission to this course, you must achieve the higher College requirement in the appropriate English language qualification. For details of the minimum grades required to achieve this requirement, please see the English language requirements for postgraduate applicants.

How to apply

We will start considering applications in October. We consider applications in batches and make a proportion of offers at a set point each month, starting from November.

It takes four to six weeks to process an application and make a decision. Shortlisted candidates will then be invited to interview.

Please note that there is not a set application deadline for this course but we strongly encourage candidates to apply before 1 July.

How to apply

Choosing your course

This course is divided into three progressional levels of study:

  • PG Certificate (PG Cert)
  • PG Diploma (PG Dip)
  • MSc

Each level of study has its own separate entry point; you can apply to any level in the first instance.

Read more about Postgraduate Certificate, Diploma and MSc degrees

Making an application

All applicants to our Master's courses must apply online.

For full details on the online application process, please visit the admissions website.

ATAS certificate

An ATAS certificate is not required for overseas students applying for this course.

Tuition fees and funding

The level of tuition fees you pay is based on your fee status, which we assess based on UK government legislation.

For more information on the funding opportunities that are available, please visit our Fees and Funding website.

Tuition fees and funding

Tuition fees (Home and EU students)

2020 entry

MSc

Full fee - £12,000
Top-up fee* - £4,000

Postgraduate Diploma (PG Dip)

Full fee - £8,000
Top-up fee* - £4,000

Postgraduate Certificate (PG Cert)

Full fee - £4,000

* If you have already completed one of the above qualifications and are moving on to the next level of study, e.g. you've already completed the PG Cert and want to study the PG Dip, you will only need to pay the top-up fee for the course you’re applying for.

You may apply to enter this programme at any level of study.

If you enter the MSc, without having studied the PG Cert or PG Dip, then you will pay the full fee listed for the MSc.

If you enter at the PG Cert or PG Dip level and return in future academic years to complete a higher award, you will pay the top-up fee advertised in the year of your return, instead of the full fee for your chosen course.

If you continue uninterrupted from one award to the next, you will pay the relevant top-up fee, plus any annual inflationary increases applied to the entry fee. This applies to applicants who originally entered for a PG Dip or MSc. This does not apply to those who have completed a PG Cert or PG Dip and are re-entering for a higher award.

The measure of inflation used will be the Retail Price Index (RPI) value in the April of the calendar year in which the academic session starts e.g. the RPI value for April 2020 will apply to fees for the academic year 2020–2021.

You could be eligible for a Postgraduate Master’s Loan from the UK government if you apply for the MSc in the first instance.

PG Cert and PG Diploma students are not eligible for the Master's loan since each of these programmes are not worth 90 ECTS credits, which is one of the eligibility criteria for this loan.

Tuition fees (Overseas and Islands students)

2020 entry

MSc

Full fee - £35,600
Top-up fee* - £7,200

Postgraduate Diploma (PG Dip)

Full fee - £28,400
Top-up fee* - £10,600

Postgraduate Certificate (PG Cert)

Full fee - £17,800

* If you have already completed one of the above qualifications and are moving on to the next level of study, e.g. you've already completed the PG Cert and want to study the PG Dip, you will only need to pay the top-up fee for the course you’re applying for.

You may apply to enter this programme at any level of study.

If you enter the MSc, without having studied the PG Cert or PG Dip, then you will pay the full fee listed for the MSc.

If you enter at the PG Cert or PG Dip level and return in future academic years to complete a higher award, you will pay the top-up fee advertised in the year of your return, instead of the full fee for your chosen course.

If you continue uninterrupted from one award to the next, you will pay the relevant top-up fee, plus any annual inflationary increases applied to the entry fee. This applies to applicants who originally entered for a PG Dip or MSc. This does not apply to those who have completed a PG Cert or PG Dip and are re-entering for a higher award.

The measure of inflation used will be the Retail Price Index (RPI) value in the April of the calendar year in which the academic session starts e.g. the RPI value for April 2020 will apply to fees for the academic year 2020–2021.

You could be eligible for a Postgraduate Master’s Loan from the UK government if you apply for the MSc in the first instance.

PG Cert and PG Diploma students are not eligible for the Master's loan since each of these programmes are not worth 90 ECTS credits, which is one of the eligibility criteria for this loan.

Postgraduate Master's loan

If you are a Home or EU student who meets certain criteria, you may be able to apply for a Postgraduate Master’s Loan of up to £10,280 from the UK government. The loan is not means-tested, and you can choose whether to put it towards your tuition fees or living costs.

You must apply for the MSc in this course in order to be eligible for a Postgraduate Master's Loan.

Scholarships

We offer a range of scholarships for postgraduate students to support you through your studies. Try our scholarships search tool to see what you might be eligible for.

There are a number of external organisations also offer awards for Imperial students, find out more about non-Imperial scholarships.

Accommodation and living costs

Living costs, including accommodation, are not included in your tuition fees.

You can compare costs across our different accommodation options on our Accommodation website.

A rough guide to what you might expect to spend to live in reasonable comfort in London is available on our Fees and Funding website.

Further information

Microbiome

Got a question?

Enquiries
Eleanor Wilde (Course Administrator)
T: +44 (0)20 7594 7767
E: genomic@imperial.ac.uk

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