Research

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Synthetic Biology underpins advances in the bioeconomy

Biological systems - including the simplest cells - exhibit a broad range of functions to thrive in their environment. Research in the Imperial College Centre for Synthetic Biology is focused on the possibility of engineering the underlying biochemical processes to solve many of the challenges facing society, from healthcare to sustainable energy. In particular, we model, analyse, design and build biological and biochemical systems in living cells and/or in cell extracts, both exploring and enhancing the engineering potential of biology. 

As part of our research we develop novel methods to accelerate the celebrated Design-Build-Test-Learn synthetic biology cycle. As such research in the Centre for Synthetic Biology highly multi- and interdisciplinary covering computational modelling and machine learning approaches; automated platform development and genetic circuit engineering ; multi-cellular and multi-organismal interactions, including gene drive and genome engineering; metabolic engineering; in vitro/cell-free synthetic biology; engineered phages and directed evolution; and biomimetics, biomaterials and biological engineering.

Publications

Citation

BibTex format

@article{Bernier:2022:10.1016/j.tim.2022.03.003,
author = {Bernier, L and Stan, G and Junier, P and Stanley, C},
doi = {10.1016/j.tim.2022.03.003},
journal = {Trends in Microbiology},
pages = {515--518},
title = {Spores-on-a-chip: new frontiers for spore research},
url = {http://dx.doi.org/10.1016/j.tim.2022.03.003},
volume = {30},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - In recent years, microfluidic technologies have become widespread in biological science. However, the suitability of this technique for understanding different aspects of spore research has hardly been considered. Herein, we review recent developments in 'spores-on-a-chip' technologies, highlighting how they could be exploited to drive new frontiers in spore research.
AU  - Bernier,L
AU  - Stan,G
AU  - Junier,P
AU  - Stanley,C
DO  - 10.1016/j.tim.2022.03.003
EP  - 518
PY  - 2022///
SN  - 0966-842X
SP  - 515
TI  - Spores-on-a-chip: new frontiers for spore research
T2  - Trends in Microbiology
UR  - http://dx.doi.org/10.1016/j.tim.2022.03.003
UR  - http://hdl.handle.net/10044/1/96004
VL  - 30
ER  -
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