Research

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Synthetic Biology underpins advances in the bioeconomy

Biological systems - including the simplest cells - exhibit a broad range of functions to thrive in their environment. Research in the Imperial College Centre for Synthetic Biology is focused on the possibility of engineering the underlying biochemical processes to solve many of the challenges facing society, from healthcare to sustainable energy. In particular, we model, analyse, design and build biological and biochemical systems in living cells and/or in cell extracts, both exploring and enhancing the engineering potential of biology. 

As part of our research we develop novel methods to accelerate the celebrated Design-Build-Test-Learn synthetic biology cycle. As such research in the Centre for Synthetic Biology highly multi- and interdisciplinary covering computational modelling and machine learning approaches; automated platform development and genetic circuit engineering ; multi-cellular and multi-organismal interactions, including gene drive and genome engineering; metabolic engineering; in vitro/cell-free synthetic biology; engineered phages and directed evolution; and biomimetics, biomaterials and biological engineering.

Publications

Citation

BibTex format

@article{Dickinson:2014:10.1007/978-3-319-00846-2_327,
author = {Dickinson, RJ and Kitney, RI},
doi = {10.1007/978-3-319-00846-2_327},
journal = {IFMBE Proceedings},
pages = {1322--1325},
title = {Information driven care pathways and procedures},
url = {http://dx.doi.org/10.1007/978-3-319-00846-2_327},
volume = {41},
year = {2014}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - The paper addresses the issue of the implementation of care pathways in electronic form. Within the National Health Service (NHS) of England, Care Pathways are becoming increasingly important. These are typically provided by the Department of Health. The Pathways provided are in the form of paper-based schema. They either have to be implemented via paper forms or, as presented here, in electronic form. In addition, care pathways must be seen in the context of the TModel of health care which comprises the care continuum and the biological continuum. The two care pathways which had been chosen as exemplars are myocardial infarction and stroke. However, the objective of the paper is not to discuss the specific care pathways in detail, but, rather, to describe technology which has been developed for their electronic implementation. The result of this implementation is that all the data and information acquired from the implementation of the care pathway is stored in a single clinical information system (CIS), which has incorporated in it the SQL database. Another important element of the system which has been developed is the ability to display data and information in terms of two dashboards (i.e. single screens which show the most important information). The two dashboards display clinical information (the point of care dashboard) and management information (the management dashboard). © Springer International Publishing Switzerland 2014.
AU  - Dickinson,RJ
AU  - Kitney,RI
DO  - 10.1007/978-3-319-00846-2_327
EP  - 1325
PY  - 2014///
SN  - 1680-0737
SP  - 1322
TI  - Information driven care pathways and procedures
T2  - IFMBE Proceedings
UR  - http://dx.doi.org/10.1007/978-3-319-00846-2_327
VL  - 41
ER  -
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