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Citation

BibTex format

@article{Lanyon-Hogg:2016:10.1016/j.dib.2016.02.012,
author = {Lanyon-Hogg, T and Masumoto, N and Bodakh, G and Konitsiotis, AD and Thinon, E and Rodgers, UR and Owens, RJ and Magee, AI and Tate, EW},
doi = {10.1016/j.dib.2016.02.012},
journal = {Data in Brief},
pages = {257--281},
title = {Synthesis and characterisation of 5-acyl-6,7-dihydrothieno[3,2-c]pyridine inhibitors of Hedgehog acyltransferase},
url = {http://dx.doi.org/10.1016/j.dib.2016.02.012},
volume = {7},
year = {2016}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - In this data article we describe synthetic and characterisation data for four members of the 5-acyl-6,7-dihydrothieno[3,2-c]pyridine (termed “RU-SKI”) class of inhibitors of Hedgehog acyltransferase, including associated NMR spectra for final compounds. RU-SKI compounds were selected for synthesis based on their published high potencies against the enzyme target. RU-SKI 41 (9a), RU-SKI 43 (9b), RU-SKI 101 (9c), and RU-SKI 201 (9d) were profiled for activity in the related article “Click chemistry armed enzyme linked immunosorbent assay to measure palmitoylation by Hedgehog acyltransferase” (Lanyon-Hogg et al., 2015) [1]. 1H NMR spectral data indicate different amide conformational ratios between the RU-SKI inhibitors, as has been observed in other 5-acyl-6,7-dihydrothieno[3,2-c]pyridines. The synthetic and characterisation data supplied in the current article provide validated access to the class of RU-SKI inhibitors.
AU - Lanyon-Hogg,T
AU - Masumoto,N
AU - Bodakh,G
AU - Konitsiotis,AD
AU - Thinon,E
AU - Rodgers,UR
AU - Owens,RJ
AU - Magee,AI
AU - Tate,EW
DO - 10.1016/j.dib.2016.02.012
EP - 281
PY - 2016///
SN - 2352-3409
SP - 257
TI - Synthesis and characterisation of 5-acyl-6,7-dihydrothieno[3,2-c]pyridine inhibitors of Hedgehog acyltransferase
T2 - Data in Brief
UR - http://dx.doi.org/10.1016/j.dib.2016.02.012
UR - http://hdl.handle.net/10044/1/29712
VL - 7
ER -