SARS-CoV-2

In 2020, the Barclay lab is responding to the pandemic by pivoting from influenza to study the novel coronavirus, SARS-CoV-2.  Our research on SARS-CoV-2 includes basic virology, serology, immunology and environmental sampling.  This is a brief list of the lab's coronavirus papers and media appearances.


Research/Papers

Clinical and laboratory evaluation of SARS-CoV-2 lateral flow assays for use in a national COVID-19 seroprevalence survey
Barnaby FlowerJonathan C BrownBryony SimmonsMaya MosheRebecca FriseRebecca PennRuthiran KugathasanClaire PetersenAnna DauntDeborah AshbySteven RileyChristina Joanne AtchisonGraham P TaylorSutha SatkunarajahLenny NaarRobert KlaberAnjna BadhanCarolina RosadasMaryam KhanNatalia FernandezMacià Sureda-VivesHannah M CheesemanJessica O'HaraGianluca FontanaScott J C PallettMichael RaymentRachael JonesLuke S P MooreMyra O McClurePeter CherepanovRichard TedderHutan AshrafianRobin ShattockHelen WardAra DarziPaul ElliotWendy S BarclayGraham S Cooke
Thorax

Investigating SARS-CoV-2 surface and air contamination in an acute healthcare setting during the peak of the COVID-19 pandemic in London
Jie Zhou, Jonathan A Otter, James R Price, Cristina Cimpeanu, Danel Meno Garcia, James Kinross, Piers R Boshier, Sam Mason, Frances Bolt, Alison H Holmes & Wendy S. Barclay
Clinical Infectious Diseases

Self-amplifying RNA SARS-CoV-2 lipid nanoparticle vaccine candidate induces high neutralizing antibody titers in mice
Paul F. McKayKai HuAnna K. BlakneyKarnyart SamnuanJonathan C. BrownRebecca PennJie ZhouClément R. BoutonPaul RogersKrunal PolraPaulo J. C. LinChristopher BarbosaYing K. TamWendy S. Barclay & Robin J. Shattock
Nature Communications

ACE2: The Only Thing That Matters?
Raul Y. Sanchez-David, Olivia C. Swann, Thomas P. Peacock & Wendy S. Barclay
American Journal of Respiratory and Critical Care Medicine

The Dynamics of Humoral Immune Responses Following SARS-CoV-2 Infection and the Potential for Reinfection
Paul Kellam and Wendy Barclay
Journal of General Virology


Media Appearances

May 2020
Serology team getting some hard-earned recognition from the BBC.  Read the article here.
Wendy was featured in the BBC Horizon - Coronavirus Special.
The lab was featured on the 6 o'clock news.

March 2020
Rebecca and Wendy are featured as taking part in Imperial's COVID-19 response for International Women's Day.  Read about them here.
Wendy is quoted in the New Scientist on why children get less ill from the coronavirus.

February 2020
As the SARS-CoV-2 outbreak continues apace, Wendy updates on what we know about the novel Coronavirus for the BMJ.  Watch here.

January 2020
Wendy discussing the current state of play with the novel coronavirus on Health Check on the BBC World Service. Listen here.