Imperial College London
Portrait Picture

ProfessorAndrewBush

Faculty of Medicine, National Heart & Lung Institute

Professor of Paediatric Respirology
 
 
 
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Contact

 

+44 (0)20 7352 8121 ext 2255a.bush

 
 
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Location

 

Chelsea WingRoyal Brompton Campus

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Summary

 

Publications

Publication Type
Year
to

1247 results found

Bush A, Frey U, Teague WG, 2011, Special problems of severe asthma in childhood, DIFFICULT-TO-TREAT SEVERE ASTHMA, Editors: Chung, Bel, Wenzel, Publisher: EUROPEAN RESPIRATORY SOCIETY, Pages: 59-81

Book chapter

Chatwin M, Bush A, Simonds AK, 2011, Outcome of goal-directed non-invasive ventilation and mechanical insufflation/exsufflation in spinal muscular atrophy type I., Arch Dis Child, Vol: 96, Pages: 426-432, ISSN: 1468-2044

Background There are widely discrepant views on the respiratory management of infants with spinal muscular atrophy (SMA) type I. Typically, management is palliative. Design A descriptive study of interventions and investigations is reported that were offered to a cohort of 13 children with SMA type I referred to our centre. Interventions and investigations included sleep studies, provision of non-invasive positive pressure ventilation (NIPPV) for ventilatory support/dependency and for physiotherapy and the use of mechanical insufflation/exsufflation (MI-E). Results NIPPV was provided for the following indications: continuous positive airways pressure flow driver dependency (n=3), nocturnal hypoventilation (n=3), to enable successful extubation (n=2), in anticipation of respiratory decompensation (n=3), and oxygen dependency/decompensation (n=2). NIPPV and MI-E were used for successful protocol-led extubations (n=9) but not non protocol-led successes (n=3). NIPPV was essential for discharge home in patients with ventilatory dependency (n=7) and was used for palliation of respiratory symptoms (n=4). Chest wall shape improved with NIPPV. The parents of children who died (n=5) were positive about the use of these techniques. Conclusion NIPPV can be used to facilitate discharge home, and MI-E is helpful in this group. This symptom and goal-directed approach can be used to inform medical decision making and to help parents make informed choices about the appropriateness of respiratory interventions in SMA type I.

Journal article

Harris JM, Bush A, Wilson N, Mills P, White C, Moffat S, Shread L, Cullinan Pet al., 2010, PRESCHOOL WHEEZING PHENOTYPES IN A REPRESENTATIVE UK BIRTH COHORT, British-Thoracic-Society-Winter-Meeting 2010, Publisher: BMJ PUBLISHING GROUP, Pages: A39-A39, ISSN: 0040-6376

Conference paper

Chudleigh J, Hoo A-F, Prasad SA, Ahmed D, Bush A, Wallis C, Stocks Jet al., 2010, FEASIBILITY OF RECRUITING NEWBORN BABIES WITH CYSTIC FIBROSIS DIAGNOSED BY NEWBORN SCREENING TO A CLINICAL STUDY WITH INVASIVE OUTCOME MEASURES, Publisher: B M J PUBLISHING GROUP, Pages: A107-A108, ISSN: 0040-6376

Conference paper

Kuehni CE, Frischer T, Strippoli M-PF, Maurer E, Bush A, Nielsen KG, Escribano A, Lucas JSA, Yiallouros P, Omran H, Eber E, O'Callaghan C, Snijders D, Barbato Aet al., 2010, Factors influencing age at diagnosis of primary ciliary dyskinesia in European children, EUROPEAN RESPIRATORY JOURNAL, Vol: 36, Pages: 1248-1258, ISSN: 0903-1936

Journal article

O'Reilly R, Oates T, Zhu J, Jeffery PK, Bush A, Saglani Set al., 2010, INCREASED RETICULAR BASEMENT MEMBRANE THICKNESS BUT NOT AIRWAY SMOOTH MUSCLE IN ENDOBRONCHIAL BIOPSIES OF SEVERE PRESCHOOL WHEEZERS, British-Thoracic-Society-Winter-Meeting 2010, Publisher: B M J PUBLISHING GROUP, Pages: A2-A3, ISSN: 0040-6376

Conference paper

Bossley CJ, Regamey N, Fleming L, Oates T, Lloyd C, Bush A, Saglani Set al., 2010, RELATIONSHIP BETWEEN BRONCHIAL RETICULAR BASEMENT MEMBRANE THICKNESS (RBM) AND SMOOTH MUSCLE MASS IN CHILDHOOD SEVERE ASTHMA (SA), British-Thoracic-Society-Winter-Meeting 2010, Publisher: B M J PUBLISHING GROUP, Pages: A40-A41, ISSN: 0040-6376

Conference paper

Naderi K, Donovan J, Brown S, Leaver N, Tan H-L, Alton EWFW, Bush A, Davies JCet al., 2010, REDUCED AIRWAY BETA-DEFENSIN 2 LEVELS IN CHILDREN WITH CYSTIC FIBROSIS AND VITAMIN D-DEFICIENCY, Publisher: B M J PUBLISHING GROUP, Pages: A107-A107, ISSN: 0040-6376

Conference paper

Frith J, Fleming L, Bossley C, Ullmann N, Bush Aet al., 2010, THE COMPLEXITIES OF DEFINING ATOPY IN SEVERE CHILDHOOD ASTHMA, Publisher: B M J PUBLISHING GROUP, Pages: A108-A108, ISSN: 0040-6376

Conference paper

Bossley CJ, Oates T, Regamey N, Fleming L, Lloyd C, Bush A, Saglani Set al., 2010, MAST CELL MYOSITIS IS ASSOCIATED WITH PERSISTENT AIRFLOW LIMITATION (PAL) IN CHILDHOOD SEVERE ASTHMA (SA), British-Thoracic-Society-Winter-Meeting 2010, Publisher: B M J PUBLISHING GROUP, Pages: A41-A41, ISSN: 0040-6376

Conference paper

Hunninghake GM, Soto-Quiros ME, Avila L, Kim HP, Lasky-Su J, Rafaels N, Ruczinski I, Beaty TH, Mathias RA, Barnes KC, Wilk JB, O'Connor GT, Gauderman WJ, Vora H, Baurley JW, Gilliland F, Liang C, Sylvia JS, Klanderman BJ, Sharma SS, Himes BE, Bossley CJ, Israel E, Raby BA, Bush A, Choi AM, Weiss ST, Celedon JCet al., 2010, <i>TSLP</i> polymorphisms are associated with asthma in a sex-specific fashion, ALLERGY, Vol: 65, Pages: 1566-1575, ISSN: 0105-4538

Journal article

Sonnappa S, Bastardo CM, Bush A, Aurora Pet al., 2010, Exhaled Nitric Oxide Measurements From Different Analyzers, CHEST, Vol: 138, Pages: 1275-1277, ISSN: 0012-3692

Journal article

Bush A, Davies J, 2010, Cystic fibrosis: to ion transport and beyond, EUROPEAN RESPIRATORY JOURNAL, Vol: 36, Pages: 991-992, ISSN: 0903-1936

Journal article

Malmberg LP, Malmstrom K, Kotaniemi-Syrjanen A, Lindahl H, Kajosaari M, Turpeinen M, Haahtela T, Saglani S, Bush A, Jeffery PK, Pelkonen AS, Makela MJet al., 2010, Does tidal exhaled nitric oxide reflect mucosal airway inflammation in infants?, THORAX, Vol: 65, Pages: 1027-1027, ISSN: 0040-6376

Journal article

Bousquet J, Mantzouranis E, Cruz AA, Ait-Khaled N, Baena-Cagnani CE, Bleecker ER, Brightling CE, Burney P, Bush A, Busse WW, Casale TB, Chan-Yeung M, Chen R, Chowdhury B, Chung KF, Dahl R, Drazen JM, Fabbri LM, Holgate ST, Kauffmann F, Haahtela T, Khaltaev N, Kiley JP, Masjedi MR, Mohammad Y, O'Byrne P, Partridge MR, Rabe KF, Togias A, van Weel C, Wenzel S, Zhong N, Zuberbier Tet al., 2010, Uniform definition of asthma severity, control, and exacerbations: Document presented for the World Health Organization Consultation on Severe Asthma, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Vol: 126, Pages: 926-938, ISSN: 0091-6749

Journal article

Johnson J-A, Bush A, Buchdahl R, 2010, Does Presenting With Meconium Ileus Affect the Prognosis of Children With Cystic Fibrosis?, PEDIATRIC PULMONOLOGY, Vol: 45, Pages: 951-958, ISSN: 8755-6863

Journal article

Moffatt MF, Gut IG, Demenais F, Strachan DP, Bouzigon E, Heath S, von Mutius E, Farrall M, Lathrop M, Cookson WOCM, Kumar A, Burney P, Jarvis D, Wjst M, Kogevinas M, Jogi R, Janson C, Franklin KA, Omenaas E, Leynaert B, Pin I, Heinrich J, Probst-Hensch NM, Anto JM, Sunyer J, Maldonado J-A, Martinez-Moratalla J, Urrutia I, Payo F, Kauffmann F, Dizier M-H, Siroux V, Boznanski A, Braun-Fahrlaender C, Genuneit J, Glas J, Horak E, Kabesch M, Pillai SG, Helms PJ, Carlsen K, Carlsen K-H, Gerritsen J, Silverman M, Sly P, Tsanakas J, Von Berg A, Whyte M, Blumenthal M, Imboden M, Rochat T, Thun GA, Gerbase MW, Curjuric I, Gaspoz J-M, Liu L-JS, Wouters IM, Sigsgaard T, Heederik D, Basinas I, Schlunssen V, Omland O, Cullinan P, Vermeulen R, Henderson J, Granell R, McArdle WL, Smith GD, James AL, Hui J, Palmer LJ, Beilby J, Musk AW, Laprise C, Hudson TJ, Lemire M, Daley D, Becker A, Chan-Yeung M, Sandford A, Kozyrskyj AL, Pare P, Ferguson A, Dimich-Ward H, Watson WT, Freidin MB, Bragina EI, Deev IA, Deeva EV, Kobyakova OS, Puzyrev VP, Ogorodova LM, Khusnutdinova EK, Karunas AS, Fedorova YY, Hall IP, Sayers I, Tobin MD, Wan YI, Heaney LG, Al-Momani BAH, Mansur AH, Manney S, Thomson NC, Chaudhuri R, Brightling CE, Bafadhel M, Singapuri A, Niven R, Simpson A, Holloway JW, Howarth PH, Polonikov AV, Ivanov VP, Solodilova MA, Melen E, Pershagen G, Bergstroem A, Kull I, Nyberg F, Wickman M, Soderhall C, Kere J, Postma DS, Kerkhof M, Brunekreef B, Smit HA, de Jongste JC, Wijga A, Aalberse RC, Hoekstra MO, Koppelman GH, Binia A, Chung KF, Bhavsar P, Chow F, Macedo P, Menzies-Gow A, van Stiphout N, Bush A, Lee Y-A, Esparza-Gordillo J, Nickel R, Wahn U, Lau S, Marenholz I, Haahtela T, von Hertzen L, Jousilahti P, Laatikainen T, Makela MJ, Vartiainen E, Laitinen T, Balding DJ, Peden JF, Corda E, Lechner D, Besse C, Zelenika D, Boland A, Bacq D, Demonchy S, Blanche H, Kamatani Y, von Mutius E, Farrall M, Lathrop M, Cookson WOCMet al., 2010, A Large-Scale, Consortium-Based Genomewide Association Study of Asthma, NEW ENGLAND JOURNAL OF MEDICINE, Vol: 363, Pages: 1211-1221, ISSN: 0028-4793

Journal article

Bush A, Saglani S, 2010, Management of severe asthma in children, LANCET, Vol: 376, Pages: 814-825, ISSN: 0140-6736

Journal article

Sonnappa S, Bastardo CM, Wade A, Saglani S, McKenzie SA, Bush A, Aurora Pet al., 2010, Symptom-pattern phenotype and pulmonary function in preschool wheezers, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Vol: 126, Pages: 519-U201, ISSN: 0091-6749

Journal article

Hedlin G, Eber E, Aurora P, Carlsen KCL, Ratjen F, Dankert-Roels JE, Ross-Russell RI, Turner S, Midulla F, Baraldi E, Bush Aet al., 2010, Paediatric respiratory disease: past, present and future Paediatric Assembly contribution to the celebration of 20 years of the ERS, EUROPEAN RESPIRATORY JOURNAL, Vol: 36, Pages: 225-228, ISSN: 0903-1936

Journal article

Vasu V, Ude C, Shah V, Lim E, Bush Aet al., 2010, Novel Surgical Technique for Insertion of Pleuroperitoneal Shunts for Bilateral Chylous Effusions in Ex Preterm Infant at Term Corrected Age, PEDIATRIC PULMONOLOGY, Vol: 45, Pages: 840-843, ISSN: 8755-6863

Journal article

Bush A, Bossley C, Fleming L, Wilson Net al., 2010, Avoiding common mistakes in the management of asthma: or, is the child a WADDLER?, Paediatrics and Child Health, Vol: 20, Pages: 344-346, ISSN: 1751-7222

Journal article

Carlsen K-H, Hedlin G, Bush A, 2010, Childhood asthma in the Year of the Lung, EUROPEAN RESPIRATORY JOURNAL, Vol: 36, Pages: 6-7, ISSN: 0903-1936

Journal article

Rutledge J, Bush A, Shekerdemian L, Schulze-Neick I, Penny D, Cai S, Li Jet al., 2010, Validity of the LaFarge equation for estimation of oxygen consumption in ventilated children with congenital heart disease younger than 3 years-A revisit, AMERICAN HEART JOURNAL, Vol: 160, Pages: 109-114, ISSN: 0002-8703

Journal article

Hedlin G, Bush A, Carlsen KL, Wennergren G, de Benedictis FM, Melen E, Paton J, Wilson N, Carlsen K-Het al., 2010, Problematic severe asthma in children, not one problem but many: a GA<SUP>2</SUP>LEN initiative, EUROPEAN RESPIRATORY JOURNAL, Vol: 36, Pages: 196-201, ISSN: 0903-1936

Journal article

Sacco O, Gambini C, Gardella C, Toma P, Rossi UG, Jasonni V, Bush A, Rossi GAet al., 2010, "Atypical Steroid Response" in a Pulmonary Inflammatory Myofibroblastic Tumor, PEDIATRIC PULMONOLOGY, Vol: 45, Pages: 721-726, ISSN: 8755-6863

Journal article

McPherson H, Rosenthal M, Bush A, 2010, Can Mucoid <i>Pseudomonas aeruginosa</i> Be Eradicated in Children With Cystic Fibrosis?, PEDIATRIC PULMONOLOGY, Vol: 45, Pages: 566-568, ISSN: 8755-6863

Journal article

Pifferi M, Bush A, Di Cicco M, Pradal U, Ragazzo V, Macchia P, Boner ALet al., 2010, Health-related quality of life and unmet needs in patients with primary ciliary dyskinesia, EUROPEAN RESPIRATORY JOURNAL, Vol: 35, Pages: 787-794, ISSN: 0903-1936

Journal article

Smyth AR, Barbato A, Beydon N, Bisgaard H, de Boeck K, Brand P, Bush A, Fauroux B, de Jongste J, Korppi M, O'Callaghan C, Pijnenburg M, Ratjen F, Southern K, Spencer D, Thomson A, Vyas H, Warris A, Merkus PJet al., 2010, Respiratory medicines for children: current evidence, unlicensed use and research priorities, EUROPEAN RESPIRATORY JOURNAL, Vol: 35, Pages: 247-265, ISSN: 0903-1936

Journal article

Bossley CJ, Hogg C, Stoneham S, Jacques TS, Bush Aet al., 2010, A Fatal Case of Cough, PEDIATRIC PULMONOLOGY, Vol: 45, Pages: 205-207, ISSN: 8755-6863

Journal article

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