Imperial College London
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Professor Anthony Gordon

Faculty of Medicine, Department of Surgery & Cancer

Chair in Anaesthesia and Critical Care
 
 
 
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Contact

 

anthony.gordon

 
 
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Location

 

ICUQueen Elizabeth the Queen Mother Wing (QEQM)St Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{McNamee:2016:10.1177/1751143716681035,
author = {McNamee, J and Gillies, M and Barrett, N and Agus, A and Beale, R and Bentley, A and Bodenham, A and Brett, S and Brodie, D and Finney, S and Gordon, A and Griffiths, M and Harrison, D and Jackson, C and McDowell, C and McNally, C and Perkins, G and Tunnicliffe, W and Vuylsteke, A and Walsh, T and Wise, M and Young, D and McAuley, D},
doi = {10.1177/1751143716681035},
journal = {Journal of the Intensive Care Society},
pages = {159--169},
title = {pRotective vEntilation with veno-venouS lung assisT in respiratory failure: A protocol for a multicentre randomised controlled trial of extracorporeal carbon dioxide removal in patients with acute hypoxaemic respiratory failure},
url = {http://dx.doi.org/10.1177/1751143716681035},
volume = {18},
year = {2016}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - One of the few interventions to demonstrate improved outcomes for acute hypoxaemic respiratory failure is reducing tidal volumes when using mechanical ventilation, often termed lung protective ventilation. Veno-venous extracorporeal carbon dioxide removal (vv-ECCO2R) can facilitate reducing tidal volumes. pRotective vEntilation with veno-venouS lung assisT (REST) is a randomised, allocation concealed, controlled, open, multicentre pragmatic trial to determine the clinical and cost-effectiveness of lower tidal volume mechanical ventilation facilitated by vv-ECCO2R in patients with acute hypoxaemic respiratory failure. Patients requiring intubation and mechanical ventilation for acute hypoxaemic respiratory failure will be randomly allocated to receive either vv-ECCO2R and lower tidal volume mechanical ventilation or standard care with stratification by recruitment centre. There is a need for a large randomised controlled trial to establish whether vv-ECCO2R in acute hypoxaemic respiratory failure can allow the use of a more protective lung ventilation strategy and is associated with improved patient outcomes.
AU  - McNamee,J
AU  - Gillies,M
AU  - Barrett,N
AU  - Agus,A
AU  - Beale,R
AU  - Bentley,A
AU  - Bodenham,A
AU  - Brett,S
AU  - Brodie,D
AU  - Finney,S
AU  - Gordon,A
AU  - Griffiths,M
AU  - Harrison,D
AU  - Jackson,C
AU  - McDowell,C
AU  - McNally,C
AU  - Perkins,G
AU  - Tunnicliffe,W
AU  - Vuylsteke,A
AU  - Walsh,T
AU  - Wise,M
AU  - Young,D
AU  - McAuley,D
DO  - 10.1177/1751143716681035
EP  - 169
PY  - 2016///
SN  - 1751-1437
SP  - 159
TI  - pRotective vEntilation with veno-venouS lung assisT in respiratory failure: A protocol for a multicentre randomised controlled trial of extracorporeal carbon dioxide removal in patients with acute hypoxaemic respiratory failure
T2  - Journal of the Intensive Care Society
UR  - http://dx.doi.org/10.1177/1751143716681035
UR  - http://hdl.handle.net/10044/1/44406
VL  - 18
ER  -
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