Summary
I am a Post-doctoral Research Fellow and Bioinformatician within the Paediatric Infectious Disease group. I joined Imperial as an undergraduate student in October 2014 and have since completed my Bachelors BSc (Biology), Masters (Bioinformatics) and my PhD (Infectious Disease) at the University.
My PhD specifically focused on developing new methods to predict patient prognosis from transcriptomic signatures in whole blood samples. My research area focuses on the transcriptomics of infectious disease in general, including understanding the molecular mechanisms underlying asymptomatic malaria infections and comparing human malarial infections to mouse models of disease at this level.
In 2022, I was joint-awarded, the Provosts Awards for Excellence in Animal Research along with colleagues from the section. I am currently working on RNA-Seq data generated from the DIAMONDS project and am hoping to expand the prototype analysis method developed during my PhD to a clinically viable prognostic tool.
Publications
Journals
Dunican C, Andradi-Brown C, Ebmeier S, et al., 2024, The malarial blood transcriptome: translational applications, Biochemical Society Transactions, Vol:52, ISSN:0300-5127, Pages:651-660
Ahu Prah D, Dunican C, Amoah L, et al., 2023, Asymptomatic Plasmodium falciparum infection evades triggering a host transcriptomic response, Journal of Infection, Vol:87, ISSN:0163-4453, Pages:259-262
Georgiadou A, Dunican C, Sorro-Barrio P, et al., 2022, Comparative transcriptomic analysis reveals translationally relevant processes in mouse models of malaria, Elife, Vol:11, ISSN:2050-084X
Patel H, Dunican C, Cunnington A, 2020, Predictors of outcome in childhood Plasmodium falciparum malaria, Virulence, Vol:11, ISSN:2150-5594, Pages:199-221
Conference
Georgiadou A, Barrio PS, Dunican C, et al., 2019, COMPARATIVE TRANSCRIPTOMICS IDENTIFIES PHENOTYPIC SIMILARITIES BETWEEN MOUSE MODELS AND HUMAN SEVERE MALARIA, 68th Annual Meeting of the American-Society-for-Tropical-Medicine-and-Hygiene (ASTMH), AMER SOC TROP MED & HYGIENE, Pages:8-8, ISSN:0002-9637