Imperial College London
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ProfessorDarrylOverby

Faculty of Engineering, Department of Bioengineering

Professor of Mechanobiology
 
 
 
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Contact

 

+44 (0)20 7594 6376d.overby

 
 
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Location

 

3.07Bessemer BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@inbook{Campbell:2017:10.1007/978-1-4939-7407-8_13,
author = {Campbell, IC and Sherwood, JM and Overby, DR and Hannon, BG and Read, AT and Raykin, J and Ethier, CR},
booktitle = {Glaucoma. Methods in Molecular Biology.},
doi = {10.1007/978-1-4939-7407-8_13},
editor = {Jakobs},
pages = {135--159},
publisher = {Humana Press},
title = {Quantification of Scleral Biomechanics and Collagen Fiber Alignment.},
url = {http://dx.doi.org/10.1007/978-1-4939-7407-8_13},
year = {2017}
}
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RIS format (EndNote, RefMan)

TY  - CHAP
AB  - The stiffness of the sclera is important in several ocular disorders, and there is hence a need to quantify the biomechanical properties of this tissue. Here, we present two methods for measuring the stiffness of scleral ocular tissues: ocular compliance testing and digital image correlation strain mapping. In tandem with these approaches, we provide two methods to spatially quantify the anisotropic alignment of collagen fibers making up the sclera, using second harmonic generation microscopy and small-angle light scattering. Together, these approaches allow specimen-specific measurement of tissue stiffness and collagen alignment, which are key factors in determining how the eye responds to mechanical loads.
AU  - Campbell,IC
AU  - Sherwood,JM
AU  - Overby,DR
AU  - Hannon,BG
AU  - Read,AT
AU  - Raykin,J
AU  - Ethier,CR
DO  - 10.1007/978-1-4939-7407-8_13
EP  - 159
PB  - Humana Press
PY  - 2017///
SP  - 135
TI  - Quantification of Scleral Biomechanics and Collagen Fiber Alignment.
T1  - Glaucoma. Methods in Molecular Biology.
UR  - http://dx.doi.org/10.1007/978-1-4939-7407-8_13
UR  - https://www.ncbi.nlm.nih.gov/pubmed/29190025
ER  -
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