Publications
563 results found
Huang J, Kumar S, Hanna GB, 2014, Investigation of C3-C10 aldehydes in the exhaled breath of healthy subjects using selected ion flow tube-mass spectrometry (SIFT-MS), JOURNAL OF BREATH RESEARCH, Vol: 8, ISSN: 1752-7155
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- Citations: 22
Antcliffe D, Jimenez B, Veselkov K, et al., 2014, DIAGNOSING PNEUMONIA ON THE INTENSIVE CARE UNIT WITH SERUM <SUP>1</SUP>H NMR SPECTROSCOPY, 27th Annual Congress of the European-Society-of-Intensive-Care-Medicine (ESICM), Publisher: SPRINGER, Pages: S237-S238, ISSN: 0342-4642
Foster JD, Mackenzie H, Nelson H, et al., 2014, Methods of Quality Assurance in Multicenter Trials in Laparoscopic Colorectal Surgery <i>A Systematic Review</i>, ANNALS OF SURGERY, Vol: 260, Pages: 220-229, ISSN: 0003-4932
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- Citations: 25
Chadwick G, Groene O, Hoare J, et al., 2014, A population-based, retrospective, cohort study of esophageal cancer missed at endoscopy, ENDOSCOPY, Vol: 46, Pages: 553-559, ISSN: 0013-726X
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- Citations: 39
Harris-Birtill D, Singh M, Zhou Y, et al., 2014, Gold Nanorod Reshaping using a Continuous Wave Laser, CLEO: Applications and Technology, Publisher: Optical Society of America
Avery KNL, Metcalfe C, Berrisford R, et al., 2014, The feasibility of a randomized controlled trial of esophagectomy for esophageal cancer - the ROMIO (Randomized Oesophagectomy: Minimally Invasive or Open) study: protocol for a randomized controlled trial, TRIALS, Vol: 15
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- Citations: 51
Cuschieri A, Hanna GB, 2014, Meta-Analysis of D1 Versus D2 Gastrectomy for Gastric Adenocarcinoma: Let Us Move on to Another Era, ANNALS OF SURGERY, Vol: 259, Pages: E90-E90, ISSN: 0003-4932
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- Citations: 23
Mackenzie H, Miskovic D, Ni M, et al., 2014, Predictive validity of objective technical assessment within the National Training Programme for laparoscopic colorectal surgery, Annual Meeting of the Society-of-Academic-and-Research-Surgery, Publisher: WILEY-BLACKWELL, Pages: 44-45, ISSN: 0007-1323
Chadwick G, Groene O, Markar SR, et al., 2014, Systematic review comparing radiofrequency ablation and complete endoscopic resection in treating dysplastic Barrett's esophagus: a critical assessment of histologic outcomes and adverse events, GASTROINTESTINAL ENDOSCOPY, Vol: 79, Pages: 718-+, ISSN: 0016-5107
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- Citations: 49
Abbassi-Ghadi N, Veselkov K, Kumar S, et al., 2014, Discrimination of lymph node metastases using desorption electrospray ionisation-mass spectrometry imaging: a proof of concept study, Annual Meeting of the Society-of-Academic-and-Research-Surgery, Publisher: WILEY-BLACKWELL, Pages: 44-44, ISSN: 0007-1323
Cocker DM, Mavroveli S, Hanna G, 2014, Metacognition In surgical skills learning, Annual Meeting of the Society-of-Academic-and-Research-Surgery, Publisher: WILEY-BLACKWELL, Pages: 20-20, ISSN: 0007-1323
Elsaddig M, Arya S, Kudo H, et al., 2014, A pilot study investigating the ability of advanced bipolar RF device to induce blood vessel haemostasis by activation of the coagulation pathway, Annual Meeting of the Society-of-Academic-and-Research-Surgery, Publisher: WILEY-BLACKWELL, Pages: 34-34, ISSN: 0007-1323
Cocker DM, Mavroveli S, Hanna G, 2014, The feasibility of applying metacognitive learning strategies to enhance simulation-based learning, Annual Meeting of the Society-of-Academic-and-Research-Surgery, Publisher: WILEY-BLACKWELL, Pages: 19-19, ISSN: 0007-1323
Kumar S, Huang J, Abbassi-Ghadi N, et al., 2014, SIFT-MS analysis of exhaled breath for volatile organic profiling of oesophago-gastric cancer, Annual Meeting of the Society-of-Academic-and-Research-Surgery, Publisher: WILEY-BLACKWELL, Pages: 17-18, ISSN: 0007-1323
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- Citations: 4
Singh M, Harris-Birtill D, Gallina M, et al., 2014, Application of Gold Nanorods for Photothermal Effect in Upper Gastrointestinal Cancer Tissue., International Surgical Congress of the Association of Surgeons of Great Britain and Ireland, Publisher: ASGBI
Abbassi-Ghadi N, Veselkov K, Kumar S, et al., 2014, Discrimination of lymph node metastases using desorption electrospray ionisation-mass spectrometry imaging, Chemical Communications, Vol: 50, Pages: 3661-3664, ISSN: 1359-7345
Desorption electrospray ionisation mass spectrometry imaging (DESI-MSI) has been used for the identification of cancer within lymph nodes with accurate spatial distribution in comparison to gold standard matched immuno-histopathological images. The metabolic profile of the cancerous lymph nodes was similar to that of the primary tumour site.
Cole SJ, Mackenzie H, Ha J, et al., 2014, Erratum to: Randomized controlled trial on the effect of coaching in simulated laparoscopic training., Surg Endosc, Vol: 28
Cole SJ, Mackenzie H, Ha J, et al., 2014, Randomized controlled trial on the effect of coaching in simulated laparoscopic training, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, Vol: 28, Pages: 979-986, ISSN: 0930-2794
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- Citations: 48
Arya S, Markar SR, Karthikesalingam A, et al., 2014, The impact of pyloric drainage on clinical outcome following esophagectomy: a systematic review, DISEASES OF THE ESOPHAGUS, Vol: 28, Pages: 326-335, ISSN: 1120-8694
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- Citations: 64
Fakhry M, Bello F, Hanna GB, 2014, Real Time Cancer Prediction Based on Objective Tissue Compliance Measurement in Endoscopic Surgery, ANNALS OF SURGERY, Vol: 259, Pages: 369-373, ISSN: 0003-4932
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- Citations: 2
Singh M, Harris-Birtill D, Gallina M, et al., 2014, Application of Gold Nanorods for Photothermal Effect in Upper Gastrointestinal Cancer Tissue, International Surgical Congress of the Association of Surgeons of Great Britain and Ireland
Su L, Fonseca MB, Arya S, et al., 2014, Laser-induced tissue fluorescence in radiofrequency tissue-fusion characterization, JOURNAL OF BIOMEDICAL OPTICS, Vol: 19, ISSN: 1083-3668
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- Citations: 12
Leff DR, Petrou G, Mavroveli S, et al., 2013, Improving training in breast surgical oncology: The development and preliminary validation of a simulator for wide local excision, Publisher: AMER ASSOC CANCER RESEARCH, ISSN: 0008-5472
Markar SR, Arya S, Karthikesalingam A, et al., 2013, Technical Factors that Affect Anastomotic Integrity Following Esophagectomy: Systematic Review and Meta-analysis, ANNALS OF SURGICAL ONCOLOGY, Vol: 20, Pages: 4274-4281, ISSN: 1068-9265
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- Citations: 141
Pabary R, Kumar S, Huang J, et al., 2013, SIFT-MS ANALYSIS AS A NON-INVASIVE DETERMINANT OF PSEUDOMONAS AERUGINOSA INFECTION IN PATIENTS WITH CYSTIC FIBROSIS, Winter Meeting of the British-Thoracic-Society, Publisher: BMJ PUBLISHING GROUP, Pages: A8-A8, ISSN: 0040-6376
Abbassi-Ghadi N, Kumar S, Huang J, et al., 2013, Metabolomic profiling of oesophago-gastric cancer: A systematic review, European Journal of Cancer Care, Vol: 49, Pages: 3625-3637, ISSN: 0961-5423
AimsThis review aims to identify metabolomic biomarkers of oesophago-gastric (OG) cancer in human biological samples, and to discuss the dominant metabolic pathways associated with the observed changes.MethodsA systematic review of the literature, up to and including 9th November 2012, was conducted for experimental studies investigating the metabolomic profile of human biological samples from patients with OG cancer compared to a control group. Inclusion criteria for analytical platforms were mass spectrometry or nuclear magnetic resonance spectroscopy. The QUADAS-2 tool was used to assess the quality of the included studies.ResultsTwenty studies met the inclusion criteria and samples utilised for metabolomic analysis included tissue (n = 11), serum (n = 8), urine (n = 1) and gastric content (n = 1). Several metabolites of glycolysis, the tricarboxylic acid cycle, anaerobic respiration and protein/lipid metabolism were found to be significantly different between cancer and control samples. Lactate and fumurate were the most commonly recognised biomarkers of OG cancer related to cellular respiration. Valine, glutamine and glutamate were the most commonly identified amino acid biomarkers. Products of lipid metabolism including saturated and un-saturated free fatty acids, ketones and aldehydes and triacylglycerides were also identified as biomarkers of OG cancer. Unclear risk of bias for patient selection was reported for the majority of studies due to the lack of clarity regarding patient recruitment.ConclusionThe application of metabolomics for biomarker detection in OG cancer presents new opportunities for the purposes of screening and therapeutic monitoring. Future studies should provide clear details of patient selection and develop metabolite assays suitable for progress beyond phase 1 pre-clinical exploratory studies.
Badran I, Sodergren M, Huf S, et al., 2013, An evaluation of outcomes of oesophago-gastric cancer in octogenarians - Retrospective review of a regional cancer network., Int J Surg, Vol: 11
Pabary R, Huang J, Kumar S, et al., 2013, SIFT-MS ANALYSIS OF EXHALED BREATH AS A NONINVASIVE DETERMINANT OF PSEUDOMONAS AERUGINOSA INFECTION IN CF PATIENTS, PEDIATRIC PULMONOLOGY, Vol: 48, Pages: 295-295, ISSN: 8755-6863
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- Citations: 2
Berrisford R, Barham P, Blencowe N, et al., 2013, Randomised Oesophagectomy: Minimally Invasive or Open, a feasibility study. The ROMIO trial, 17th Annual Scientific Meeting of the Association-of-Upper-Gastrointestinal-Surgeons-of-Great-Britain-and-Ireland (AUGIS), Publisher: WILEY-BLACKWELL, Pages: 37-37, ISSN: 0007-1323
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