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@article{Hollingsworth:2015:10.1186/s13071-015-1235-1,
author = {Hollingsworth, TD and Adams, ER and Anderson, RM and Atkins, K and Bartsch, S and Basanez, M-G and Behrend, M and Blok, DJ and Chapman, LAC and Coffeng, L and Courtenay, O and Crump, RE and de, Vlas SJ and Dobson, A and Dyson, L and Farkas, H and Galvani, AP and Gambhir, M and Gurarie, D and Irvine, MA and Jervis, S and Keeling, MJ and Kelly-Hope, L and King, C and Lee, BY and Le, Rutte EA and Lietman, TM and Ndeffo-Mbah, M and Medley, GF and Michael, E and Pandey, A and Peterson, JK and Pinsent, A and Porco, TC and Richardus, JH and Reimer, L and Rock, KS and Singh, BK and Stolk, W and Swaminathan, S and Torr, SJ and Townsend, J and Truscott, J and Walker, M and Zoueva, A},
doi = {10.1186/s13071-015-1235-1},
journal = {Parasites & Vectors},
title = {Quantitative analyses and modelling to support achievement of the 2020 goals for nine neglected tropical diseases},
url = {http://dx.doi.org/10.1186/s13071-015-1235-1},
volume = {8},
year = {2015}
}

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TY  - JOUR
AB  - Quantitative analysis and mathematical models are useful tools in informing strategies to control or eliminatedisease. Currently, there is an urgent need to develop these tools to inform policy to achieve the 2020 goals forneglected tropical diseases (NTDs). In this paper we give an overview of a collection of novel model-based analyseswhich aim to address key questions on the dynamics of transmission and control of nine NTDs: Chagas disease,visceral leishmaniasis, human African trypanosomiasis, leprosy, soil-transmitted helminths, schistosomiasis, lymphaticfilariasis, onchocerciasis and trachoma. Several common themes resonate throughout these analyses, including: theimportance of epidemiological setting on the success of interventions; targeting groups who are at highest risk ofinfection or re-infection; and reaching populations who are not accessing interventions and may act as a reservoirfor infection,. The results also highlight the challenge of maintaining elimination ‘as a public health problem’ whentrue elimination is not reached. The models elucidate the factors that may be contributing most to persistence ofdisease and discuss the requirements for eventually achieving true elimination, if that is possible. Overall thiscollection presents new analyses to inform current control initiatives. These papers form a base from which furtherdevelopment of the models and more rigorous validation against a variety of datasets can help to give moredetailed advice. At the moment, the models’ predictions are being considered as the world prepares for a finalpush towards control or elimination of neglected tropical diseases by 2020.
AU  - Hollingsworth,TD
AU  - Adams,ER
AU  - Anderson,RM
AU  - Atkins,K
AU  - Bartsch,S
AU  - Basanez,M-G
AU  - Behrend,M
AU  - Blok,DJ
AU  - Chapman,LAC
AU  - Coffeng,L
AU  - Courtenay,O
AU  - Crump,RE
AU  - de,Vlas SJ
AU  - Dobson,A
AU  - Dyson,L
AU  - Farkas,H
AU  - Galvani,AP
AU  - Gambhir,M
AU  - Gurarie,D
AU  - Irvine,MA
AU  - Jervis,S
AU  - Keeling,MJ
AU  - Kelly-Hope,L
AU  - King,C
AU  - Lee,BY
AU  - Le,Rutte EA
AU  - Lietman,TM
AU  - Ndeffo-Mbah,M
AU  - Medley,GF
AU  - Michael,E
AU  - Pandey,A
AU  - Peterson,JK
AU  - Pinsent,A
AU  - Porco,TC
AU  - Richardus,JH
AU  - Reimer,L
AU  - Rock,KS
AU  - Singh,BK
AU  - Stolk,W
AU  - Swaminathan,S
AU  - Torr,SJ
AU  - Townsend,J
AU  - Truscott,J
AU  - Walker,M
AU  - Zoueva,A
DO  - 10.1186/s13071-015-1235-1
PY  - 2015///
SN  - 1756-3305
TI  - Quantitative analyses and modelling to support achievement of the 2020 goals for nine neglected tropical diseases
T2  - Parasites & Vectors
UR  - http://dx.doi.org/10.1186/s13071-015-1235-1
UR  - http://hdl.handle.net/10044/1/28759
VL  - 8
ER  -

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