Imperial College London

Professor SirMagdiYacoub

Faculty of MedicineNational Heart & Lung Institute

Emeritus Professor
 
 
 
//

Contact

 

+44 (0)1895 828 893m.yacoub

 
 
//

Location

 

Heart Science Centre, HarefieldHarefield HospitalHarefield Hospital

//

Summary

 

Publications

Citation

BibTex format

@article{Gehani:2014:10.5339/gcsp.2014.35,
author = {Gehani, A and Al-Suwaidi, J and Yacoub, M},
doi = {10.5339/gcsp.2014.35},
journal = {Global Cardiology Science and Practice},
title = {NIAMI: Towards the optimization of results in primary PCI},
url = {http://dx.doi.org/10.5339/gcsp.2014.35},
volume = {2014},
year = {2014}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - The NAIMI trial has recently been published (1). It assessed one of the most contemporary and challenging issues in the management of acute myocardial infarction (AMI), namely prevention of reperfusion injury (RPI) after primary PCI for STLelevation myocardial infarction (STEMI). It investigated the effect of the intravenous administration of Na nitrite given immediately prior to primary PCI for STEMI in 229 patients (118 in the treatment group, and 111 in placebo). The myocardial infarction (MI) size did not differ between the two groups as observed by cardiac MRI (CMR) with gadolinium enhancement at 6L8 days or plasma TroponinLI and creatine kinase (CK), or by left ventricular (LV) volume and ejection fraction (EF) as measured by echocardiography at 6L8 days and again at 6 months. They concluded that IV nitrites did not reduce the infarct size. There was, however, a trend towards benefit in diabetic patients in the postLhoc analysis. The small number of these subjects has probably lead to inconclusive outcome in this subset.
AU - Gehani,A
AU - Al-Suwaidi,J
AU - Yacoub,M
DO - 10.5339/gcsp.2014.35
PY - 2014///
TI - NIAMI: Towards the optimization of results in primary PCI
T2 - Global Cardiology Science and Practice
UR - http://dx.doi.org/10.5339/gcsp.2014.35
VL - 2014
ER -