Imperial College London
Alternate

Professor SirMagdiYacoub

Faculty of Medicine, National Heart & Lung Institute

Emeritus Professor
 
 
 
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Contact

 

+44 (0)1895 828 893m.yacoub

 
 
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Location

 

Heart Science Centre, HarefieldHarefield HospitalHarefield Hospital

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Summary

 

Publications

Citation

BibTex format

@article{Nasr:2017:10.1136/heartjnl-2016-310251,
author = {Nasr, E and Ibrahim, M and Yacoub, M},
doi = {10.1136/heartjnl-2016-310251},
journal = {Heart},
title = {Heart failure in a neonate with multiple cardiac masses.},
url = {http://dx.doi.org/10.1136/heartjnl-2016-310251},
volume = {103},
year = {2017}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - CLINICAL INTRODUCTION: A 16-day-old male neonate weighing 3.4kg presented with severe heart failure. His heart rate was 190/min, normal sinus rhythm, blood pressure was 55/30mmHg and respiratory rate was 65/min. Transthoracic echocardiography and cardiac MRI showed multiple intracardiac masses; the largest was filling most of the left ventricular cavity (figure 1A) (see online supplementary video 1 and figure S1), measuring around 2.8cm×1.8cm and arising from the apical septum. Left ventricular function was moderately impaired with an ejection fraction of 40%. Due to accelerated haemodynamic instability, the mass was excised surgically. Through left ventriculotomy, a large mass could be identified which was attached with a pedicle to the apical septum. This mass was excised with its pedicle.During early postoperative course, the patient developed subdural and intraventricular haemorrhage, necessitating insertion of a ventriculoperitoneal shunt. MRI of the brain showed dark-signalled subependymal nodules and multiple cortical patches of high T2 signals (see online supplementary figure S2). The patient had no neurological sequelae and was discharged home.The patient was discharged home with no neurological sequelae. During the 2-year follow-up period, serial echocardiograms showed regression of the rest of the cardiac tumours and improvement of cardiac functions (see online supplementary figure S3). However, fibrous plaques were observed on the child's forehead. QUESTION: What is the most likely diagnosis? HibernomaFibromaRhabdomyomaRhabdomyosarcoma.
AU  - Nasr,E
AU  - Ibrahim,M
AU  - Yacoub,M
DO  - 10.1136/heartjnl-2016-310251
PY  - 2017///
TI  - Heart failure in a neonate with multiple cardiac masses.
T2  - Heart
UR  - http://dx.doi.org/10.1136/heartjnl-2016-310251
UR  - https://www.ncbi.nlm.nih.gov/pubmed/27655257
VL  - 103
ER  -
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