Imperial College London

DrMarkSullivan

Faculty of MedicineDepartment of Metabolism, Digestion and Reproduction

Senior Lecturer
 
 
 
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Contact

 

+44 (0)20 7594 2133mark.sullivan Website

 
 
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Location

 

G-027Institute of Reproductive and Developmental BiologyHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Helmig:1990:10.3109/00016349009013302,
author = {Helmig, R and Roseblade, CK and Uldbjerg, N and Elder, MG and Sullivan, MH},
doi = {10.3109/00016349009013302},
journal = {Acta Obstet Gynecol Scand},
pages = {405--408},
title = {Control of fetal membrane prostaglandin E2 production by bacteria.},
url = {http://dx.doi.org/10.3109/00016349009013302},
volume = {69},
year = {1990}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - The effect of bacteria on the production of prostaglandin E2 (PGE2) and PGE2 metabolites by fetal membranes has been investigated. Live bacteria stimulated a large increase in the levels of PGE2 metabolites, but only a small increase in the levels of PGE2 on the fetal side of the membranes. No significant changes in the levels of PGE2 or its metabolites were found on the maternal side. Bacteria may therefore stimulate PGE2 production by fetal membranes during short-term incubations, but it seems that the metabolic capacity of the chorion was so high that no change in PGE2 levels was detectable on the maternal side of the fetal membranes. This was confirmed by the finding that less than 1% of 3H-PGE2 added to the fetal side of the membrane reached the maternal side without being metabolized.
AU - Helmig,R
AU - Roseblade,CK
AU - Uldbjerg,N
AU - Elder,MG
AU - Sullivan,MH
DO - 10.3109/00016349009013302
EP - 408
PY - 1990///
SN - 0001-6349
SP - 405
TI - Control of fetal membrane prostaglandin E2 production by bacteria.
T2 - Acta Obstet Gynecol Scand
UR - http://dx.doi.org/10.3109/00016349009013302
UR - https://www.ncbi.nlm.nih.gov/pubmed/2270765
VL - 69
ER -