Imperial College London
Alternate

Professor MENGXING TANG

Faculty of Engineering, Department of Bioengineering

Professor of Biomedical Imaging
 
 
 
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Contact

 

+44 (0)20 7594 3664mengxing.tang Website

 
 
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Location

 

3.13Royal School of MinesSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Li:2015:10.1364/BOE.6.001954,
author = {Li, S and Cheng, Y and Eckersley, RJ and Elson, DS and Tang, M-X},
doi = {10.1364/BOE.6.001954},
journal = {Biomedical Optics Express},
pages = {1954--1962},
title = {Dual shear wave induced laser speckle contrast signal and the improvement in shear wave speed measurement},
url = {http://dx.doi.org/10.1364/BOE.6.001954},
volume = {6},
year = {2015}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Shear wave speed is quantitatively related to tissue viscoelasticity.Previously we reported shear wave tracking at centimetre depths ina turbid optical medium using laser speckle contrast detection. Shear waveprogression modulates displacement of optical scatterers and therefore modulatesphoton phase and changes the laser speckle patterns. Time-resolvedcharge-coupled device (CCD)-based speckle contrast analysis was used totrack shear waves and measure the time-of-flight of shear waves for speedmeasurement. In this manuscript, we report a new observation of the laserspeckle contrast difference signal for dual shear waves. A modulation ofCCD speckle contrast difference was observed and simulation reproducesthe modulation pattern, suggesting its origin. Both experimental andsimulation results show that the dual shear wave approach generates animproved definition of temporal features in the time-of-flight optical signaland an improved signal to noise ratio with a standard deviation less than50% that of individual shear waves. Results also show that dual shear wavescan correct the bias of shear wave speed measurement caused by shear wavereflections from elastic boundaries.
AU  - Li,S
AU  - Cheng,Y
AU  - Eckersley,RJ
AU  - Elson,DS
AU  - Tang,M-X
DO  - 10.1364/BOE.6.001954
EP  - 1962
PY  - 2015///
SN  - 2156-7085
SP  - 1954
TI  - Dual shear wave induced laser speckle contrast signal and the improvement in shear wave speed measurement
T2  - Biomedical Optics Express
UR  - http://dx.doi.org/10.1364/BOE.6.001954
UR  - http://hdl.handle.net/10044/1/37066
VL  - 6
ER  -
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