Imperial College London


Faculty of MedicineDepartment of Brain Sciences

Clinical Professor of Molecular Medicine



+44 (0)20 3313 8310r.festenstein




Ms Hyacinth Henry +44 (0)20 3313 3172




London Institute of Medical Sciences, Mansfield BuildingNeptune BuildingHammersmith Campus





Professor Festenstein is an associate of the Medical Research Council's Clinical Sciences Centre (  a member of the Division of Brain Sciences and the Section of Translational Neurosciences, Imperial College and an Honorary Consultant at the Imperial College Health Care Trust and the National Hospital for Neurology and Neurosurgery, Queen Square, London.

Guest Lectures

Reversing FXN gene silencing in vivo in humans -towards a disease-modifying therapy?, International Ataxia Research Conference 2015, Windsor, 2015

Epigenetics and Disease: "Antagonising heterochromatin formation in Friedreich's ataxia: a novel therapy for a prototypic position-effect disease?", Gordon Reserach Conference on Epigenetics, Bryant University, Smithfield, Rhode Island, USA, 2013

Epigenetic mechanisms and genetic diseases, College de France, College de france, 2013

International Conference on Ataxia: Proteasome inhibition restores RNA Polymerase II stalling at the Friedreich’s ataxia gene and rescues Frataxin expression, Ataxia UK, London, 2012

7th International Conference on Unstable Microsatellites and Disease: Breaking the Silence in Friedreich's ataxia, IGBMC, Strasbourg, 2012

Gender bias and diseases: which genetic mechanisms?: Not just sex: Sex chromosome complement effects independent of phenotypic sex determine autosomal gene expression differences, College de France, College de France, Paris, France, 2011

Current Research into the Ataxias’ - FASI/Ataxia UK research conference: Breaking the Silence in Friedreich's ataxia, Ataxia UK/ FASI, Ataxi UK/FASI International Conference on Ataxia, The Stillorgan Park Hotel, Co. Dublin, Ireland., 2008