Summary
Susanne Sattler obtained her PhD in 2009 from the University of Vienna, Austria. Her PhD project on immunological properties of endothelial cells sparked her interest in the mutual cross talk between the immune and the cardiovascular system.
Susanne Sattler joined Imperial College London in 2009 as a postdoctoral research associate in the Centre of Complement and Inflammation Research (CCIR). There she developed a keen interest in the regulatory control of immune responses as well as autoimmunity as an inevitable consequence of lacking or aberrant regulatory processes. In 2012, Susanne joined the National Heart and Lung Institute (NHLI) as a member of the Cardiac Regeneration group led by Prof. Nadia Rosenthal.
Susanne was promoted to independent Research Fellow in 2017 and now leads the NHLI cardio-immunology team investigating the crosstalk between the adaptive immune system and the heart.
Publications
Journals
Racine JJ, Bachman JF, Zhang J-G, et al., 2024, Murine MHC-Deficient Nonobese Diabetic Mice Carrying Human HLA-DQ8 Develop Severe Myocarditis and Myositis in Response to Anti-PD-1 Immune Checkpoint Inhibitor Cancer Therapy., J Immunol, Vol:212, Pages:1287-1306
Sattler S, 2024, Is ischaemic heart failure an autoimmune disease?, Esc Heart Failure, Vol:11, ISSN:2055-5822, Pages:611-614
Sattler S, 2024, Finding the right balance on the challenging path to clinical translation of anti-inflammatory therapies for ischemic heart disease, Nature Cardiovascular Research, Vol:3, Pages:245-247
Racine JJ, Misherghi A, Dwyer JR, et al., 2023, HLA-DQ8 Supports Development of Insulitis Mediated by Insulin-Reactive Human TCR-Transgenic T Cells in Nonobese Diabetic Mice., J Immunol, Vol:211, Pages:1792-1805
De Winter N, Ji J, Sintou A, et al., 2023, Myocardial injury causes changes in the transcriptional and regulatory landscape of adaptive immune cells in the heart, European Heart Journal, Vol:44, ISSN:0195-668X