Imperial College London

Professor Tony Cass

Faculty of Natural SciencesDepartment of Chemistry

Senior Research Investigator
 
 
 
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Contact

 

+44 (0)20 7594 5195t.cass

 
 
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Location

 

301KMolecular Sciences Research HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@inbook{Maniyam:2016,
author = {Maniyam, MN and Yaacob, NS and Sjahrir, F and Nagarajan, J and Nagarajan, J and Cass, AEG and Nawawi, NM and Ibrahim, AL},
booktitle = {Biodegradation: Properties, Analysis and Performance},
pages = {1--77},
title = {Rhodococcus UKMP-5M: A versatile bioremediation microorganism},
year = {2016}
}

RIS format (EndNote, RefMan)

TY  - CHAP
AB - Wastes generated from the industrial sectors over the years raised significant environmental and health concerns. Soon, interest in bioremediation as biological methods to clean-up pollution escalated due to their environmentally-friendly approach and less capital and operative costs as compared to that of chemical and physical methods. The genus Rhodococcus emerges as one of the most promising groups of microorganisms besides pseudomonads capable of transforming or degrading complex synthetic substrates with remarkable stability and toxicity. Thus, Rhodococcus strains may be utilized as industrial organisms, primarily for biotransformation and biodegradation since they are equipped with a rich source of potential green chemistry enzymatic catalysts, unique cell wall structure and applicable biotechnological properties. However, research on actinomycetes microbiology particularly the genus Rhodococcus is in its infancy especially in Malaysia and the present research will be the first in-depth analysis of the rhodococcal clade present in Peninsular Malaysia, an area of tropical rather than temperate climate. This project has successfully isolated 23 Rhodococcus strains from various sources in Peninsular Malaysia and there is significant sequence evidence to support the emergence of 9 (or more) new species from these Malaysian samples. Sequencing of one of the Malaysian isolates namely Rhodococcus UKMP-5M had led to the identification of groups of genes that are associated with the production of enzymes which have potential for industrial application as biocatalysts. Rhodococcus UKMP-5M serves as a versatile bioremediation microorganism since this single locally isolated strain was capable of degradation of phenol, chlorinated compounds, nitrile and cyanide which are classified as toxic and harmful chemical substances through enzymatic reaction. In addition, this particular strain was also competent in transforming waste cooking oil into biodiesel. Hence, the present
AU - Maniyam,MN
AU - Yaacob,NS
AU - Sjahrir,F
AU - Nagarajan,J
AU - Nagarajan,J
AU - Cass,AEG
AU - Nawawi,NM
AU - Ibrahim,AL
EP - 77
PY - 2016///
SN - 9781634857512
SP - 1
TI - Rhodococcus UKMP-5M: A versatile bioremediation microorganism
T1 - Biodegradation: Properties, Analysis and Performance
ER -