Imperial College London
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ProfessorThomasChurcher

Faculty of Medicine, School of Public Health

Professor of Infectious Disease Dynamics
 
 
 
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Contact

 

thomas.churcher

 
 
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Location

 

G35Medical SchoolSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Lissenden:2021:10.3390/insects12090826,
author = {Lissenden, N and Kont, MD and Essandoh, J and Ismail, HM and Churcher, TS and Lambert, B and Lenhart, A and McCall, PJ and Moyes, CL and Paine, MJI and Praulins, G and Weetman, D and Lees, RS},
doi = {10.3390/insects12090826},
journal = {Insects},
title = {Review and meta-analysis of the evidence for choosing between specific pyrethroids for programmatic purposes},
url = {http://dx.doi.org/10.3390/insects12090826},
volume = {12},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Pyrethroid resistance is widespread in malaria vectors. However, differential mortality in discriminating dose assays to different pyrethroids is often observed in wild populations. When this occurs, it is unclear if this differential mortality should be interpreted as an indication of differential levels of susceptibility within the pyrethroid class, and if so, if countries should consider selecting one specific pyrethroid for programmatic use over another. A review of evidence from molecular studies, resistance testing with laboratory colonies and wild populations, and mosquito behavioural assays were conducted to answer these questions. Evidence suggested that in areas where pyrethroid resistance exists, different results in insecticide susceptibility assays with specific pyrethroids currently in common use (deltamethrin, permethrin, α-cypermethrin, and λ-cyhalothrin) are not necessarily indicative of an operationally relevant difference in potential performance. Consequently, it is not advisable to use rotation between these pyrethroids as an insecticide-resistance management strategy. Less commonly used pyrethroids (bifenthrin and etofenprox) may have sufficiently different modes of action, though further work is needed to examine how this may apply to insecticide resistance management
AU  - Lissenden,N
AU  - Kont,MD
AU  - Essandoh,J
AU  - Ismail,HM
AU  - Churcher,TS
AU  - Lambert,B
AU  - Lenhart,A
AU  - McCall,PJ
AU  - Moyes,CL
AU  - Paine,MJI
AU  - Praulins,G
AU  - Weetman,D
AU  - Lees,RS
DO  - 10.3390/insects12090826
PY  - 2021///
SN  - 2075-4450
TI  - Review and meta-analysis of the evidence for choosing between specific pyrethroids for programmatic purposes
T2  - Insects
UR  - http://dx.doi.org/10.3390/insects12090826
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000699818800001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://www.mdpi.com/2075-4450/12/9/826
UR  - http://hdl.handle.net/10044/1/94284
VL  - 12
ER  -
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