Imperial College London

DrWilliamMan

Faculty of MedicineNational Heart & Lung Institute

Reader in Respiratory Medicine
 
 
 
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Contact

 

+44 (0)1895 828 851w.man

 
 
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Location

 

Harefield HospitalHarefield Hospital

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Summary

 

Publications

Citation

BibTex format

@article{Patel:2019:10.1183/13993003.01264-2018,
author = {Patel, S and Cole, AD and Nolan, CM and Barker, RE and Jones, SE and Kon, S and Cairn, J and Loebinger, M and Wilson, R and Man, WD-C},
doi = {10.1183/13993003.01264-2018},
journal = {European Respiratory Journal},
title = {Pulmonary rehabilitation in bronchiectasis: a propensity-matched study},
url = {http://dx.doi.org/10.1183/13993003.01264-2018},
volume = {53},
year = {2019}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - International guidelines recommend pulmonary rehabilitation for patients with bronchiectasis, supported by small trials and data extrapolated from chronic obstructive pulmonary disease (COPD). However, it is unknown whether real-life data on completion rates and response to pulmonary rehabilitation are similar between patients with bronchiectasis and COPD.Using propensity score matching, 213 consecutive patients with bronchiectasis referred for a supervised pulmonary rehabilitation programme were matched 1:1 with a control group of 213 patients with COPD. Completion rates, change in incremental shuttle walk (ISW) distance and change in Chronic Respiratory Disease Questionnaire (CRQ) score with pulmonary rehabilitation were compared between groups.Completion rate was the same in both groups (74%). Improvements in ISW distance and most domains of the CRQ with pulmonary rehabilitation were similar between the bronchiectasis and COPD groups (ISW distance: 70 versus 63m; CRQ-Dyspnoea: 4.8 versus 5.3; CRQ-Emotional Function: 3.5 versus 4.6; CRQ-Mastery: 2.3 versus 2.9; all p>0.20). However, improvements in CRQ-Fatigue with pulmonary rehabilitation were greater in the COPD group (bronchiectasis 2.1 versus COPD 3.3; p=0.02).In a real-life, propensity-matched control study, patients with bronchiectasis show similar completion rates and improvements in exercise and health status outcomes as patients with COPD. This supports the routine clinical provision of pulmonary rehabilitation to patients with bronchiectasis.
AU - Patel,S
AU - Cole,AD
AU - Nolan,CM
AU - Barker,RE
AU - Jones,SE
AU - Kon,S
AU - Cairn,J
AU - Loebinger,M
AU - Wilson,R
AU - Man,WD-C
DO - 10.1183/13993003.01264-2018
PY - 2019///
SN - 0903-1936
TI - Pulmonary rehabilitation in bronchiectasis: a propensity-matched study
T2 - European Respiratory Journal
UR - http://dx.doi.org/10.1183/13993003.01264-2018
UR - https://www.ncbi.nlm.nih.gov/pubmed/30578381
UR - http://hdl.handle.net/10044/1/66486
VL - 53
ER -