Imperial College London
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ProfessorAdnanCustovic

Faculty of Medicine, National Heart & Lung Institute

Professor of Paediatric Allergy
 
 
 
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Contact

 

a.custovic CV

 
 
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Location

 

220Medical SchoolSt Mary's Campus

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Summary

 

Publications

Publication Type
Year
to

687 results found

Durrell B, Bishop S, Gore RB, Woodcock A, Custovic Aet al., 2001, Domestic vacuum cleaning increases cat allergen exposure in homes with cats, Publisher: BRITISH MED JOURNAL PUBL GROUP, Pages: 34-34, ISSN: 0040-6376

Conference paper

Scrivener S, Yemaneberhan H, Zebenigus M, Tilahun D, Girma S, Ali S, McElroy P, Custovic A, Woodcock A, Pritchard D, Venn A, Britton Jet al., 2001, Independent effects of intestinal parasites infection and domestic allergen exposure on risk of wheeze in Ethiopia: a nested case-control study, LANCET, Vol: 358, Pages: 1493-1499, ISSN: 0140-6736

Journal article

Custovic A, Woodcock A, 2001, Environmental allergen exposure and asthma: prospects for primary prevention, Mediators of Inflammation, Vol: 10, Pages: 295-298, ISSN: 0962-9351

Journal article

Murray CS, Woodcock A, Custovic A, 2001, The role of indoor allergen exposure in the development of sensitization and asthma, Current Opinion in Allergy and Clinical Immunology, Vol: 1, Pages: 407-412, ISSN: 1528-4050

Journal article

Custovic A, Hallam CL, Simpson BM, Craven M, Simpson A, Woodcock Aet al., 2001, Decreased prevalence of sensitization to cats with high exposure to cat allergen, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Vol: 108, Pages: 537-539, ISSN: 0091-6749

Journal article

Murray CS, Woodcock A, Custovic A, 2001, The role of indoor allergen exposure in the development of sensitization and asthma, CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY, Vol: 1, Pages: 407-412, ISSN: 1528-4050

Journal article

Addo-Yobo EOD, Custovic A, Taggart SCO, Craven M, Bonnie B, Woodcock Aet al., 2001, Risk factors for asthma in urban Ghana, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Vol: 108, Pages: 363-368, ISSN: 0091-6749

Journal article

Woodcock A, Addo-Yobo EOD, Taggart SCO, Craven M, Custovic Aet al., 2001, Pet allergen levels in homes in Ghana and the United Kingdom, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Vol: 108, Pages: 463-465, ISSN: 0091-6749

Journal article

Smillie FI, Elderfield AJ, Patel F, Cain G, Tavenier G, Brutsche M, Craven M, Custovic A, Woodcock Aet al., 2001, Lymphoproliferative responses in cord blood and at one year:: no evidence for the effect of <i>in utero</i> exposure to dust mite allergens, CLINICAL AND EXPERIMENTAL ALLERGY, Vol: 31, Pages: 1194-1204, ISSN: 0954-7894

Journal article

Liccardi G, Custovic A, Cazzola M, Russo M, D'Amato M, D'Amato Get al., 2001, Avoidance of allergens and air pollutants in respiratory allergy, ALLERGY, Vol: 56, Pages: 705-722, ISSN: 0105-4538

Journal article

Custovic A, Simpson BM, Simpson A, Kissen P, Woodcock Aet al., 2001, Effect of environmental manipulation in pregnancy and early life on respiratory symptoms and atopy during first year of life: a randomised trial, LANCET, Vol: 358, Pages: 188-193, ISSN: 0140-6736

Journal article

Bornehag CG, Bonini S, Custovic A, Kunzli N, Malmberg P, Matricardi P, Skerfving S, Sigsgaard T, Verhoeff A, Sundell Jet al., 2001, Dampness in buildings as a risk factor for health effects, EUROEXPO - Multidisciplinary review of the literature (1988-2000) on dampness and mite exposure in buildings and health effects, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: S94-S94, ISSN: 1044-3983

Conference paper

Simpson A, Woodcock A, Custovic A, 2001, Housing characteristics and mite allergen levels: to humidity and beyond, CLINICAL AND EXPERIMENTAL ALLERGY, Vol: 31, Pages: 803-805, ISSN: 0954-7894

Journal article

Custovic A, Woodcock A, 2001, On allergens and asthma (again): does exposure to allergens in homes exacerbate asthma?, CLINICAL AND EXPERIMENTAL ALLERGY, Vol: 31, Pages: 670-673, ISSN: 0954-7894

Journal article

Custovic A, Woodcock A, 2001, Exposure and sensitization in infants and children, Current Opinion in Allergy and Clinical Immunology, Vol: 1, Pages: 133-138, ISSN: 1528-4050

Journal article

Brutsche MH, Brutsche IC, Wood P, Mogulkoc N, Custovic A, Egan J, Woodcock Aet al., 2001, B-cell isotype control in atopy and asthma assessed with cDNA array technology, AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, Vol: 280, Pages: L627-L637, ISSN: 1040-0605

Journal article

Custovic A, Woodcock A, 2001, Exposure and sensitization in infants and children, CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY, Vol: 1, Pages: 133-138, ISSN: 1528-4050

Journal article

Simpson BM, Custovic A, Simpson A, Hallam CL, Walsh D, Marolia H, Campbell J, Woodcock Aet al., 2001, NAC Manchester Asthma and Allergy Study (<SUP>NAC</SUP>MAAS):: risk factors for asthma and allergic disorders in adults, CLINICAL AND EXPERIMENTAL ALLERGY, Vol: 31, Pages: 391-399, ISSN: 0954-7894

Journal article

Simpson BM, Custovic A, Simpson A, Hallam CL, Walsh D, Marolia HM, Campbell JM, Woodcock Aet al., 2001, NAC Manchester Asthma and Allergy Study: Risk factors for asthma and allergic disorders in adults, Publisher: MOSBY, INC, Pages: S144-S144, ISSN: 0091-6749

Conference paper

Smillie FI, Patel FY, Tavernier G, Cain G, Elderfield AJ, Simpson BM, Gore RB, Murray C, Kissen PM, Custovic A, Woodcock Aet al., 2001, Lymphoproliferative responses at birth and one year of age and wheeze during the first year of life, Publisher: MOSBY, INC, Pages: S297-S297, ISSN: 0091-6749

Conference paper

Gore RB, Hadi EA, Craven M, Smillie FI, O'Meara TJ, Tovey ER, Custovic A, Woodcock Aet al., 2001, Intra-nasal air sampling and reservoir house dust in the quantitation of dermatophagoides pteronyssinus exposure, Publisher: MOSBY, INC, Pages: S220-S220, ISSN: 0091-6749

Conference paper

Al-Mousawi M, Lovel HHJ, Al-Bader ALA, Behbehani N, Al Dowaisan AR, Arifhodzic N, Khadar A, Craven M, Custovic A, Woodcock Aet al., 2001, Domestic allergens in public places in Kuwait, a desert country, Publisher: MOSBY, INC, Pages: S26-S26, ISSN: 0091-6749

Conference paper

Murray C, Smillie FI, Lowe L, Cain G, Kissen PM, Custovic A, Woodcock Aet al., 2001, Environmental tobacco smoke exposure and recurrent wheeze in the first year of life in infants at high risk of atopy, Publisher: MOSBY, INC, Pages: S145-S145, ISSN: 0091-6749

Conference paper

Lowe L, Murray C, Custovic A, Simpson BM, Kissen PM, Woodcock Aet al., 2001, Specific airway resistance in three year old children at high, medium and low risk of atopy who have not wheezed, Publisher: MOSBY, INC, Pages: S228-S229, ISSN: 0091-6749

Conference paper

Elderfield AJ, Smillie FI, Patel FY, Cain G, Tavernier G, Simpson BM, Craven M, Custovic A, Woodcock Aet al., 2001, Lymphoproliferative responses in cord blood and at one year:: Noevidence for the effect of <i>in utero</i> exposure to dust mite allergen, Publisher: MOSBY, INC, Pages: S295-S295, ISSN: 0091-6749

Conference paper

Curbishley L, Smillie FI, Gore RB, O'Meara T, Tovey ER, Custovic A, Woodcock Aet al., 2001, Examination of immunoglobulin (IgA, IgE, IgG, IgG1, IgG4 and IgM) responses to inhaled dust particles using Inhalix personal nasal airflow samplers, Publisher: MOSBY, INC, Pages: S120-S120, ISSN: 0091-6749

Conference paper

Brutsche MH, Brutsche IC, Wood P, Brass A, Morrison N, Rattay M, Mogulkoc N, Simler N, Craven M, Custovic A, Egan JJG, Woodcock Aet al., 2001, Apoptosis signals in atopy and asthma measured with cDNA arrays, CLINICAL AND EXPERIMENTAL IMMUNOLOGY, Vol: 123, Pages: 181-187, ISSN: 0009-9104

Journal article

Brutsche MH, Brutsche IC, Wood P, Mogulkoc N, Custovic A, Egan J, Woodcock Aet al., 2001, B-cell isotype control in atopy and asthma assessed with cDNA array technology, American Journal of Physiology - Lung Cellular and Molecular Physiology, Vol: 280, ISSN: 1040-0605

B-cell isotype switching and the production of IgE is regulated by a variety of gene products through different mechanisms. A better understanding of these processes has the potential to identify markers of disease and new therapeutic targets. The aim of the study was to investigate human B-cell isotype control and IgE production in atopy and asthma with cDNA array technology. Eighteen atopic asthmatic, eight atopic nonasthmatic, and fourteen healthy control subjects were included. Peripheral blood mononuclear cells were separated by gradient centrifugation, mRNA was purified, and the reverse-transcribed probes were hybridized to cDNA membranes. Group differences were assessed with the Mann-Whitney U-test. Twenty-three of seventy-eight tested IgE-related genes had significantly altered expression in atopy and asthma compared with that in the healthy subjects. The differentially expressed genes include surface molecules involved in T- and B-cell interaction and activation, cytokines, intracellular signaling products, and transcription factors. In conclusion, both atopic nonasthmatic and atopic asthmatic individuals had activated proinflammatory pathways, a minimal requirement for B-cell isotype switching, and a clear net pro-IgE cytokine climate.

Journal article

Lowe L, Custovic A, Kissen P, Woodcock Aet al., 2001, Specific airway resistance in awake 3 year old children, Publisher: BLACKWELL SCIENCE LTD, Pages: 160-160, ISSN: 0954-7894

Conference paper

Hallam CL, Custovic A, Simpson BM, Simpson A, Craven M, Woodcock Aet al., 2001, Current allergen exposure is an important risk factors for asthma, Publisher: BLACKWELL SCIENCE LTD, Pages: 160-160, ISSN: 0954-7894

Conference paper

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