Imperial College London
Alternate

ProfessorAndreaFrilling

Faculty of Medicine, Department of Surgery & Cancer

Chair in Endocrine Surgery
 
 
 
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Contact

 

+44 (0)20 3313 3210a.frilling

 
 
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Location

 

BN2/13 B BlockHammersmith HospitalHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Clift:2023:10.1016/j.beem.2023.101798,
author = {Clift, AK and Thomas, R and Frilling, A},
doi = {10.1016/j.beem.2023.101798},
journal = {Best Pract Res Clin Endocrinol Metab},
title = {Developments in interventional management of hepatic metastases from neuroendocrine tumours.},
url = {http://dx.doi.org/10.1016/j.beem.2023.101798},
volume = {37},
year = {2023}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Neuroendocrine tumours commonly metastasise to the liver, particularly those arising from the intestinal tract and pancreas. Whilst surgery offers the only approach with intent to cure, the vast majority of patients with neuroendocrine liver metastases are ineligible. Liver-directed interventional therapies seek to exploit the patho-anatomy of the blood supply of hepatic metastases to deliver therapy to liver deposits. This may involve percutaneous ablation, bland embolization, or the selective infusion of chemotherapeutics, targeted agents or radiolabelled embolic material. Retrospective case series evidence has characterised objective response rates, disease control rates, and longer-term outcomes associated with each approach. Recent advances in this field include ongoing comparative trials of different techniques, but more importantly, combinations of interventional liver-directed therapies and other systemic therapy in multimodal treatment concepts.
AU  - Clift,AK
AU  - Thomas,R
AU  - Frilling,A
DO  - 10.1016/j.beem.2023.101798
PY  - 2023///
TI  - Developments in interventional management of hepatic metastases from neuroendocrine tumours.
T2  - Best Pract Res Clin Endocrinol Metab
UR  - http://dx.doi.org/10.1016/j.beem.2023.101798
UR  - https://www.ncbi.nlm.nih.gov/pubmed/37468404
VL  - 37
ER  -
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