Imperial College London
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ProfessorDavidFirmin

Faculty of Medicine, National Heart & Lung Institute

Emeritus Professor of Biomedical Imaging
 
 
 
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Contact

 

+44 (0)20 7351 8801d.firmin

 
 
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Location

 

Cardiovascular MR UnitRoyal Brompton Campus

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Summary

 

Publications

Citation

BibTex format

@article{Keegan:2014:10.1002/mrm.24967,
author = {Keegan, J and Drivas, P and Firmin, DN},
doi = {10.1002/mrm.24967},
journal = {Magnetic Resonance in Medicine},
pages = {779--785},
title = {Navigator artifact reduction in three-dimensional late gadolinium enhancement imaging of the atria},
url = {http://dx.doi.org/10.1002/mrm.24967},
volume = {72},
year = {2014}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - PurposeNavigator-gated three-dimensional (3D) late gadolinium enhancement (LGE) imaging demonstrates scarring following ablation of atrial fibrillation. An artifact originating from the slice-selective navigator-restore pulse is frequently present in the right pulmonary veins (PVs), obscuring the walls and making quantification of enhancement difficult. We describe a simple sequence modification to greatly reduce or remove this artifact.MethodsA navigator-gated inversion-prepared gradient echo sequence was modified so that the slice-selective navigator-restore pulse was delayed in time from the nonselective preparation (NAV-restore-delayed). Both NAV-restore-delayed and conventional 3D LGE acquisitions were performed in 11 patients and the results compared.ResultsOne patient was excluded due to severe respiratory motion artifact in both NAV-restore-delayed and conventional acquisitions. Moderate to severe artifact was present in 9 of the remaining 10 patients using the conventional sequence and was considerably reduced when using the NAV-restore-delayed sequence (ostial PV to blood pool ratio, 1.7 ± 0.5 versus 1.1 ± 0.2, respectively [P < 0.0001]; qualitative artifact scores, 2.8 ± 1.1 versus 1.2 ± 0.4, respectively [P < 0.001]). While navigator signal-to-noise ratio was reduced with the NAV-restore-delayed sequence, respiratory motion compensation was unaffected.ConclusionsShifting the navigator-restore pulse significantly reduces or eliminates navigator artifact. This simple modification improves the quality of 3D LGE imaging and potentially aids late enhancement quantification in the atria
AU  - Keegan,J
AU  - Drivas,P
AU  - Firmin,DN
DO  - 10.1002/mrm.24967
EP  - 785
PY  - 2014///
SN  - 1522-2594
SP  - 779
TI  - Navigator artifact reduction in three-dimensional late gadolinium enhancement imaging of the atria
T2  - Magnetic Resonance in Medicine
UR  - http://dx.doi.org/10.1002/mrm.24967
UR  - http://hdl.handle.net/10044/1/27339
VL  - 72
ER  -
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