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@article{Walsh:2018:10.1212/WNL.0000000000004798,
author = {Walsh, RR and Krismer, F and Galpern, WR and Wenning, GK and Low, PA and Halliday, G and Koroshetz, WJ and Holton, J and Quinn, NP and Rascol, O and Shaw, LM and Eidelberg, D and Bower, P and Cummings, JL and Abler, V and Biedenharn, J and Bitan, G and Brooks, DJ and Brundin, P and Fernandez, H and Fortier, P and Freeman, R and Gasser, T and Hewitt, A and Höglinger, GU and Huentelman, MJ and Jensen, PH and Jeromin, A and Kang, UJ and Kaufmann, H and Kellerman, L and Khurana, V and Klockgether, T and Kim, WS and Langer, C and LeWitt, P and Masliah, E and Meissner, W and Melki, R and Ostrowitzki, S and Piantadosi, S and Poewe, W and Robertson, D and Roemer, C and Schenk, D and Schlossmacher, M and Schmahmann, JD and Seppi, K and Shih, L and Siderowf, A and Stebbins, GT and Stefanova, N and Tsuji, S and Sutton, S and Zhang, J},
doi = {10.1212/WNL.0000000000004798},
journal = {Neurology},
pages = {74--82},
title = {Recommendations of the Global Multiple System Atrophy Research Roadmap Meeting.},
url = {http://dx.doi.org/10.1212/WNL.0000000000004798},
volume = {90},
year = {2018}
}

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TY  - JOUR
AB  - Multiple system atrophy (MSA) is a rare neurodegenerative disorder with substantial knowledge gaps despite recent gains in basic and clinical research. In order to make further advances, concerted international collaboration is vital. In 2014, an international meeting involving leaders in the field and MSA advocacy groups was convened in Las Vegas, Nevada, to identify critical research areas where consensus and progress was needed to improve understanding, diagnosis, and treatment of the disease. Eight topic areas were defined: pathogenesis, preclinical modeling, target identification, endophenotyping, clinical measures, imaging biomarkers, nonimaging biomarkers, treatments/trial designs, and patient advocacy. For each topic area, an expert served as a working group chair and each working group developed priority-ranked research recommendations with associated timelines and pathways to reach the intended goals. In this report, each groups' recommendations are provided.
AU  - Walsh,RR
AU  - Krismer,F
AU  - Galpern,WR
AU  - Wenning,GK
AU  - Low,PA
AU  - Halliday,G
AU  - Koroshetz,WJ
AU  - Holton,J
AU  - Quinn,NP
AU  - Rascol,O
AU  - Shaw,LM
AU  - Eidelberg,D
AU  - Bower,P
AU  - Cummings,JL
AU  - Abler,V
AU  - Biedenharn,J
AU  - Bitan,G
AU  - Brooks,DJ
AU  - Brundin,P
AU  - Fernandez,H
AU  - Fortier,P
AU  - Freeman,R
AU  - Gasser,T
AU  - Hewitt,A
AU  - Höglinger,GU
AU  - Huentelman,MJ
AU  - Jensen,PH
AU  - Jeromin,A
AU  - Kang,UJ
AU  - Kaufmann,H
AU  - Kellerman,L
AU  - Khurana,V
AU  - Klockgether,T
AU  - Kim,WS
AU  - Langer,C
AU  - LeWitt,P
AU  - Masliah,E
AU  - Meissner,W
AU  - Melki,R
AU  - Ostrowitzki,S
AU  - Piantadosi,S
AU  - Poewe,W
AU  - Robertson,D
AU  - Roemer,C
AU  - Schenk,D
AU  - Schlossmacher,M
AU  - Schmahmann,JD
AU  - Seppi,K
AU  - Shih,L
AU  - Siderowf,A
AU  - Stebbins,GT
AU  - Stefanova,N
AU  - Tsuji,S
AU  - Sutton,S
AU  - Zhang,J
DO  - 10.1212/WNL.0000000000004798
EP  - 82
PY  - 2018///
SP  - 74
TI  - Recommendations of the Global Multiple System Atrophy Research Roadmap Meeting.
T2  - Neurology
UR  - http://dx.doi.org/10.1212/WNL.0000000000004798
UR  - https://www.ncbi.nlm.nih.gov/pubmed/29237794
VL  - 90
ER  -

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