Imperial College London
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Eric Lim

Faculty of Medicine, National Heart & Lung Institute

Professor of Thoracic Surgery
 
 
 
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Contact

 

+44 (0)20 7351 8591eric.lim

 
 
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Location

 

Sydney StreetRoyal Brompton Campus

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Summary

 

Publications

Citation

BibTex format

@article{Sharkey:2015:10.14740/wjon897w,
author = {Sharkey, A and Ariyaratnam, P and Anikin, V and Belcher, E and Kendall, S and Lim, E and Naidu, B and Parry, W and Loubani, M},
doi = {10.14740/wjon897w},
journal = {World Journal of Oncology},
pages = {270--275},
title = {Thoracoscore and European Society objective score fail to predict mortality in the UK},
url = {http://dx.doi.org/10.14740/wjon897w},
volume = {6},
year = {2015}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Background: Thoracoscore and the European Society Objective Score (ESOS.01) are two scoring systems used in thoracic surgery to estimate operative mortality risk. We aimed to evaluate if these are valid tools for use in the UK population. Methods: A multi-center, prospective study was carried out on patients undergoing lung resection at six UK centers. Data were submitted electronically using our online data collection tool. Data were analyzed to determine the factors affecting mortality. A receiver operating characteristic analysis determined the ability of the thoracoscore and ESOS.01 to predict in-hospital mortality. Results: Data were complete for 2,245 patients. The observed in-hospital mortality was 31 patients (1.38%). Mean thoracoscore was 2.66 (SD ± 3.21). Gender (P = 0.004, hazard ratio 4.786) and co-morbidity score (P = 0.005, hazard ratio 3.289) were identified as risk factors for mortality. A sub-analysis was performed using data from 1,912 patients with complete data for ESOS.01. In this group, mean thoracoscore was 2.55 (SD ± 2.94), mean ESOS.01 was 2.11(SD ± 1.41), and these were statistically significantly different (P < 0.0001). The observed in-hospital mortality was 28 patients (1.46%). The c-index for thoracoscore was 0.705, and for ESOS.01 was 0.739. Conclusions: Both thoracoscore and ESOS.01 overestimated mortality in the UK population. There is a continued need to develop an appropriate risk prediction system for the UK.
AU  - Sharkey,A
AU  - Ariyaratnam,P
AU  - Anikin,V
AU  - Belcher,E
AU  - Kendall,S
AU  - Lim,E
AU  - Naidu,B
AU  - Parry,W
AU  - Loubani,M
DO  - 10.14740/wjon897w
EP  - 275
PY  - 2015///
SN  - 1920-4531
SP  - 270
TI  - Thoracoscore and European Society objective score fail to predict mortality in the UK
T2  - World Journal of Oncology
UR  - http://dx.doi.org/10.14740/wjon897w
UR  - https://www.ncbi.nlm.nih.gov/pubmed/29147415
UR  - http://hdl.handle.net/10044/1/74197
VL  - 6
ER  -
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