Imperial College London
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Professor Hani Gabra

Faculty of Medicine, Department of Surgery & Cancer

Emeritus Professor of Medical Oncology
 
 
 
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Contact

 

h.gabra Website

 
 
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Assistant

 

Ms Sophie Lions +44 (0)20 7594 2792

 
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Location

 

Garry Weston CentreCancer CentreHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Harding:2012:10.1038/bjc.2012.343,
author = {Harding, V and Fenu, E and Medani, H and Shaboodien, R and Ngan, S and Li, HK and Burt, R and Diamantis, N and Tuthill, M and Blagden, S and Gabra, H and Urch, CE and Moser, S and Agarwal, R},
doi = {10.1038/bjc.2012.343},
journal = {British Journal of Cancer},
pages = {925--930},
title = {Safety, cost-effectiveness and feasibility of daycase paracentesis in the management of malignant ascites with a focus on ovarian cancer},
url = {http://dx.doi.org/10.1038/bjc.2012.343},
volume = {107},
year = {2012}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Background:Paracentesis for malignant ascites is usually performed as an in-patient procedure, with a median length of stay (LoS) of 3–5 days, with intermittent clamping of the drain due to a perceived risk of hypotension. In this study, we assessed the safety of free drainage and the feasibility and cost-effectiveness of daycase paracentesis.Method:Ovarian cancer admissions at Hammersmith Hospital between July and October 2009 were audited (Stage 1). A total of 21 patients (Stage 2) subsequently underwent paracentesis with free drainage of ascites without intermittent clamping (October 2010–January 2011). Finally, 13 patients (19 paracenteses, Stage 3), were drained as a daycase (May–December 2011).Results:Of 67 patients (Stage 1), 22% of admissions and 18% of bed-days were for paracentesis, with a median LoS of 4 days. In all, 81% of patients (Stage 2) drained completely without hypotension. Of four patients with hypotension, none was tachycardic or symptomatic. Daycase paracentesis achieved complete ascites drainage without complications, or the need for in-patient admission in 94.7% of cases (Stage 3), and cost £954 compared with £1473 for in-patient drainage.Conclusions:Free drainage of malignant ascites is safe. Daycase paracentesis is feasible, cost-effective and reduces hospital admissions, and potentially represents the standard of care for patients with malignant ascites.
AU  - Harding,V
AU  - Fenu,E
AU  - Medani,H
AU  - Shaboodien,R
AU  - Ngan,S
AU  - Li,HK
AU  - Burt,R
AU  - Diamantis,N
AU  - Tuthill,M
AU  - Blagden,S
AU  - Gabra,H
AU  - Urch,CE
AU  - Moser,S
AU  - Agarwal,R
DO  - 10.1038/bjc.2012.343
EP  - 930
PY  - 2012///
SN  - 0007-0920
SP  - 925
TI  - Safety, cost-effectiveness and feasibility of daycase paracentesis in the management of malignant ascites with a focus on ovarian cancer
T2  - British Journal of Cancer
UR  - http://dx.doi.org/10.1038/bjc.2012.343
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000308703400005&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - http://hdl.handle.net/10044/1/71751
VL  - 107
ER  -
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