Imperial College London
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ProfessorJoaoCabral

Faculty of Engineering, Department of Chemical Engineering

Professor of Soft Matter
 
 
 
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Contact

 

+44 (0)20 7594 5571j.cabral Website

 
 
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Assistant

 

Mrs Sarah Payne +44 (0)20 7594 5567

 
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Location

 

517AACE ExtensionSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Tyagi:2022:10.1021/jacsau.2c00453,
author = {Tyagi, G and Greenfield, JL and Jones, BE and Sharratt, WN and Khan, K and Seddon, D and Malone, LA and Cowieson, N and Evans, RC and Fuchter, MJ and Cabral, JT},
doi = {10.1021/jacsau.2c00453},
journal = {JACS Au},
pages = {2670--2677},
title = {Light responsiveness and assembly of arylazopyrazole-based surfactants in neat and mixed CTAB micelles},
url = {http://dx.doi.org/10.1021/jacsau.2c00453},
volume = {2},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - The self-assembly of an arylazopyrazole-based photosurfactant (PS), based on cetyltrimethylammonium bromide (CTAB), and its mixed micelle formation with CTAB in aqueous solution was investigated by small angle neutron and X-ray scattering (SANS/SAXS) and UV–vis absorption spectroscopy. Upon UV light exposure, PS photoisomerizes from E-PS (trans) to Z-PS (cis), which transforms oblate ellipsoidal micelles into smaller, spherical micelles with larger shell thickness. Doping PS with CTAB resulted in mixed micelle formation at all stoichiometries and conditions investigated; employing selectively deuterated PS, a monotonic variation in scattering length density and dimensions of the micellar core and shell is observed for all contrasts. The concentration- and irradiance-dependence of the E to Z configurational transition was established in both neat and mixed micelles. A liposome dye release assay establishes the enhanced efficacy of photosurfactants at membrane disruption, with E-PS exhibiting a 4-fold and Z-PS a 10-fold increase in fluorescence signal with respect to pure CTAB. Our findings pave the way for external triggering and modulation of the wide range of CTAB-based biomedical and material applications.
AU  - Tyagi,G
AU  - Greenfield,JL
AU  - Jones,BE
AU  - Sharratt,WN
AU  - Khan,K
AU  - Seddon,D
AU  - Malone,LA
AU  - Cowieson,N
AU  - Evans,RC
AU  - Fuchter,MJ
AU  - Cabral,JT
DO  - 10.1021/jacsau.2c00453
EP  - 2677
PY  - 2022///
SN  - 2691-3704
SP  - 2670
TI  - Light responsiveness and assembly of arylazopyrazole-based surfactants in neat and mixed CTAB micelles
T2  - JACS Au
UR  - http://dx.doi.org/10.1021/jacsau.2c00453
UR  - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000879935100001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=a2bf6146997ec60c407a63945d4e92bb
UR  - https://pubs.acs.org/doi/10.1021/jacsau.2c00453
UR  - http://hdl.handle.net/10044/1/104982
VL  - 2
ER  -
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