Publications
257 results found
Woolhouse MEJ, Webster JP, Domingo E, et al., 2002, Biological and biomedical implications of the co-evolution of pathogens and their hosts, NATURE GENETICS, Vol: 32, Pages: 569-577, ISSN: 1061-4036
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- Citations: 578
Webster JP, 2002, Sex, snails, and schistosomes: the influence of compatibility genotype on reproductive strategy, 9th International Congress on Invertebrate Reproduction and Development, Publisher: TAYLOR & FRANCIS LTD, Pages: 261-268, ISSN: 0792-4259
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- Citations: 4
Blair L, Webster JP, 2002, Host reproductive fitness:: the influence of increasing parasite pressure in a <i>Biomphalaria glabrata/Schistosoma mansoni</i> system, 9th International Congress on Invertebrate Reproduction and Development, Publisher: INT SCIENCE SERVICES/BALABAN PUBLISHERS, Pages: 243-249, ISSN: 0168-8170
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- Citations: 6
Davies CM, Fairbrother E, Webster JP, 2002, Mixed strain schistosome infections of snails and the evolution of parasite virulence, PARASITOLOGY, Vol: 124, Pages: 31-38, ISSN: 0031-1820
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- Citations: 98
Blair L, Webster JP, 2002, Reproductive fitness: influence of increasing parasite pressure., Invertebrate Reproduction and Development, Vol: 41, Pages: 243-249
Battersby S, Parsons R, Webster JP, 2002, Urban rat infestations and the risk to public health, Environmental Health Research, Vol: 1, Pages: 57-66
Webster JP, 2002, Sex, Snails, and Schistosomes: the influence of resistance genotype on reproductive strategy., Invertebrate Reproduction and Development, Vol: 41, Pages: 261-268
Webster JP, 2001, Rats, cats, people and parasites: the impact of latent toxoplasmosis on behaviour, MICROBES AND INFECTION, Vol: 3, Pages: 1037-1045, ISSN: 1286-4579
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- Citations: 149
Webster JP, Davies CM, Ndamba J, et al., 2001, Spatio-temporal genetic variability in the schistosome intermediate host <i>Biomphalaria pfeifferi</i>, ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY, Vol: 95, Pages: 515-527, ISSN: 0003-4983
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- Citations: 11
Webster JP, 2001, Compatibility and sex in a snail-schistosome system, PARASITOLOGY, Vol: 122, Pages: 423-432, ISSN: 0031-1820
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- Citations: 19
Webster JP, Davies CM, Hoffman JI, et al., 2001, Population genetics of the schistosome intermediate host Biomphalaria pfeifferi in the Zimbabwean highveld: implications for co-evolutionary theory, ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY, Vol: 95, Pages: 203-214, ISSN: 0003-4983
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- Citations: 30
Davies CM, Webster JP, Woolhouse MEJ, 2001, Trade-offs in the evolution of virulence in an indirectly transmitted macroparasite, PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, Vol: 268, Pages: 251-257, ISSN: 0962-8452
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- Citations: 86
King EM, Drake L, Webster J, et al., 2001, IgA responses in saliva and serum against the intestinal nematode Ascaris lumbricoides, Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol: 95
Davies CM, Webster JP, Munatsi A, et al., 2001, Schistosome host-parasite population genetics in the Zimbabwean highveld., Medical and Veterinary Malacology in Africa, Editors: Madsen H, Appleton C, Chimbari, Charlottlund, Publisher: DBL publications, Pages: 62-82, ISBN: 9788798125075
Blair L, Webster JP, Davies CM, et al., 2001, An experimental evaluation of the genetic control theory for schistosomiasis, Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol: 95
Davies CM, Webster JP, 2001, A genetic trade-off of virulence and transmission in a snail-schistosome system., Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol: 95
Battersby S, Webster J, 2001, Rat infestations and public health, Environmental Health Journal, Vol: 109, Pages: 109-111
Blair L, Webster JP, Barker GC, 2001, Isolation and characterization of polymorphic microsatellite markers in Schistosoma mansoni from Africa., Molecular Ecology Notes, Vol: 1, Pages: 93-95
Webster JP, Davies CM, 2001, Coevolution and compatibility in the snail-schistosome system, PARASITOLOGY, Vol: 123, Pages: S41-S56, ISSN: 0031-1820
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- Citations: 61
Woolhouse MEJ, Webster JP, 2000, In search of the Red Queen, PARASITOLOGY TODAY, Vol: 16, Pages: 506-508, ISSN: 0169-4758
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- Citations: 18
Berdoy M, Webster JP, Macdonald DW, 2000, Fatal attraction in rats infected with Toxoplasma gondii, PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, Vol: 267, Pages: 1591-1594, ISSN: 0962-8452
Webster JP, Gowtage-Sequeira S, Berdoy M, et al., 2000, Predation of beetles (<i>Tenebrio molitor</i>) infected with tapeworms (<i>Hymenolepis diminuta</i>):: a note of caution for the Manipulation Hypothesis, PARASITOLOGY, Vol: 120, Pages: 313-318, ISSN: 0031-1820
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- Citations: 24
Hubbard LJ, Lingard J, Webster JPG, 2000, Romanian wheat prices: is there a need for stabilisation?, FOOD POLICY, Vol: 25, Pages: 55-67, ISSN: 0306-9192
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- Citations: 2
Davies CM, Webster JP, Krüger O, et al., 1999, Host-parasite population genetics:: a cross-sectional comparison of <i>Bulinus globosus</i> and <i>Schistosoma haematobium</i>, PARASITOLOGY, Vol: 119, Pages: 295-302, ISSN: 0031-1820
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- Citations: 74
Webster JPG, Bowles RG, Williams NT, 1999, Estimating the economic benefits of alternative pesticide usage scenarios: wheat production in the United Kingdom, CROP PROTECTION, Vol: 18, Pages: 83-89, ISSN: 0261-2194
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- Citations: 18
Webster JP, Woolhouse MEJ, 1999, Cost of resistance: relationship between reduced fertility and increased resistance in a snail-schistosome host-parasite system, PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, Vol: 266, Pages: 391-396, ISSN: 0962-8452
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- Citations: 142
Hurtig AK, Nicoll A, Carne C, et al., 1998, Syphilis in pregnant women and their children in the United Kingdom: results from national clinician reporting surveys 1994-7., BMJ, Vol: 317, Pages: 1617-1619, ISSN: 0959-8138
OBJECTIVE: To measure the incidence of syphilis detected in pregnancy and congenital syphilis in the United Kingdom. DESIGN: Surveys through consultants in genitourinary medicine and paediatricians with active surveillance. SETTING: United Kingdom, 1994-7. SUBJECTS: Women treated for syphilis in pregnancy, and children with early congenital syphilis born in the United Kingdom. RESULTS: Over 3 years 139 women were diagnosed with and treated for syphilis in pregnancy; 121 were detected through antenatal screening. Thirty one had confirmed or probable congenitally transmissible syphilis, putting their pregnancies at risk. These were minimum figures but are compatible with the 90 to 100 women newly diagnosed annually as having infectious or early latent syphilis. A universal screening policy would require 18 600 and 55 700 women (maximum numbers) to be screened, respectively, to detect one woman needing treatment and to prevent one case of congenital syphilis. Nine presumptive cases of children with congenital syphilis born in the United Kingdom were reported. Mothers requiring treatment for syphilis were found in almost every health region but were more prevalent in London and the south east. Being born abroad and belonging to an ethnic minority group were strong risk factors, but 14% (19 of 121) of cases treated and six of 31 definite or probably transmissible cases occurred in white women born in the United Kingdom. CONCLUSIONS: Congenitally transmissible syphilis continues to occur among pregnant women in the United Kingdom. Cases would be missed and stillbirths and congenitally infected babies would occur if antenatal screening was abandoned.
Webster JP, Woolhouse MEJ, 1998, SELECTION AND STRAIN SPECIFICITY OF COMPATIBILITY BETWEEN SNAIL INTERMEDIATE HOSTS AND THEIR PARASITIC SCHISTOSOMES., Evolution, Vol: 52, Pages: 1627-1634
Many theoretical models of host-parasite coevolution assume that variation in host resistance to parasite infection is, at least partially, genetically determined and specific to the strain of infecting parasite. However, very few experimental studies have been conducted to test this assumption in animal-parasite systems. Biomphalaria glabrata snails serve as the intermediate hosts of Schistosoma mansoni. Although some snails are resistant to infection, there is no evidence of fixation of resistance in field populations. Two possible explanations for this are high fitness costs associated with resistance and a dynamic coevolution between parasite and host, perhaps involving matching alleles or gene-for-gene interactions. Two strains of B. glabrata were artificially selected for either resistance or susceptibility to each of two strains of S. mansoni parasite for three generations. Third-generation snails were then were exposed to either the parasite strain to which they had been selected or to a different parasite strain. In both host strains, resistance and susceptibility (compatibility) were found to be heritable. Moreover, compatibility to one parasite strain was not associated with compatibility to another strain, implying no genetic trade-off. Our results are discussed in terms of potential mechanisms of resistance in this host-parasite system and their implications to general coevolutionary theory.
Webster JP, Woolhouse MEJ, 1998, Selection and strain specificity of compatibility between snail intermediate hosts and their parasitic schistosomes, EVOLUTION, Vol: 52, Pages: 1627-1634, ISSN: 0014-3820
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- Citations: 82
Hoffman JI, Webster JP, Ndamba J, et al., 1998, Extensive genetic variation revealed in adjacent populations of the schistosome intermediate host Biomphalaria pfeifferi from a single river system, ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY, Vol: 92, Pages: 693-698, ISSN: 0003-4983
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- Citations: 22
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