Imperial College London
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Professor Konstantinos Dimopoulos

Faculty of Medicine, National Heart & Lung Institute

Professor of Practice (Adult Congenital Heart Disease)
 
 
 
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Contact

 

+44 (0)20 7352 8121 ext 82771k.dimopoulos02

 
 
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Location

 

Chelsea WingRoyal Brompton Campus

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Summary

 

Publications

Citation

BibTex format

@article{Angelini:2020:10.1007/s00428-020-02779-8,
author = {Angelini, A and di, Gioia C and Doran, H and Fedrigo, M and Henriques, de Gouveia R and Ho, SY and Leone, O and Sheppard, MN and Thiene, G and Dimopoulos, K and Mulder, B and Padalino, M and van, der Wal AC and Association, for European Cardiovascular Pathology AECVP},
doi = {10.1007/s00428-020-02779-8},
journal = {Virchows Archiv: an international journal of pathology},
pages = {797--820},
title = {Autopsy in adults with congenital heart disease (ACHD).},
url = {http://dx.doi.org/10.1007/s00428-020-02779-8},
volume = {476},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - The adult congenital heart diseases (ACHD) population is exceeding the pediatric congenital heart diseases (CHD) population and is progressively expanding each year, representing more than 90% of patients with CHD. Of these, about 75% have undergone surgical and/or percutaneous intervention for palliation or correction. Autopsy can be a very challenging procedure in ACHD patients. The approach and protocol to be used may vary depending on whether the pathologists are facing native disease without surgical or percutaneous interventions, but with various degrees of cardiac remodeling, or previously palliated or corrected CHD. Moreover, interventions for the same condition have evolved over the last decades, as has perioperative myocardial preservations and postoperative care, with different long-term sequelae depending on the era in which patients were operated on. Careful clinicopathological correlation is, thus, required to assist the pathologist in performing the autopsy and reaching a diagnosis regarding the cause of death. Due to the heterogeneity of the structural abnormalities, and the wide variety of surgical and interventional procedures, there are no standard methods for dissecting the heart at autopsy. In this paper, we describe the most common types of CHDs that a pathologist could encounter at autopsy, including the various types of surgical and percutaneous procedures and major pathological manifestations. We also propose a practical systematic approach to the autopsy of ACHD patients.
AU  - Angelini,A
AU  - di,Gioia C
AU  - Doran,H
AU  - Fedrigo,M
AU  - Henriques,de Gouveia R
AU  - Ho,SY
AU  - Leone,O
AU  - Sheppard,MN
AU  - Thiene,G
AU  - Dimopoulos,K
AU  - Mulder,B
AU  - Padalino,M
AU  - van,der Wal AC
AU  - Association,for European Cardiovascular Pathology AECVP
DO  - 10.1007/s00428-020-02779-8
EP  - 820
PY  - 2020///
SN  - 0945-6317
SP  - 797
TI  - Autopsy in adults with congenital heart disease (ACHD).
T2  - Virchows Archiv: an international journal of pathology
UR  - http://dx.doi.org/10.1007/s00428-020-02779-8
UR  - https://www.ncbi.nlm.nih.gov/pubmed/32266476
UR  - https://link.springer.com/article/10.1007%2Fs00428-020-02779-8
UR  - http://hdl.handle.net/10044/1/78175
VL  - 476
ER  -
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