Imperial College London


Faculty of MedicineSchool of Public Health

Chair in Biostatistics



m.blangiardo Website




528Norfolk PlaceSt Mary's Campus






BibTex format

author = {Cai, Y and Hodgson, S and Blangiardo, M and Gulliver, J and Morley, D and Vienneau, D and de, Hoogh K and Key, T and Hveem, K and Elliott, P and Hansell, A},
journal = {ICBEN 2017 Proceedings},
title = {Road traffic noise and incident cardiovascular disease: a joint analysis of HUNT, EPIC-Oxford and UK Biobank},
url = {},
year = {2017}

RIS format (EndNote, RefMan)

AB - Aims: This study aimed to investigate the effects of long-term exposure to road traffic noise on incident CVD in three large cohorts: HUNT, EPIC-Oxford and UK Biobank. Methods: In a complete-case sample (N=361,699), 4,014 IHD and 2,109 cerebrovascular incident cases were ascertained between baseline (1993-2010) and end of follow-up (2008-2015) through medical record linkage. Annual mean road traffic noise exposure was modelled at baseline address. Individual-level covariate data were harmonised and data were pooled. Analyses used Cox proportional hazards model with adjustments for confounders, including air pollution. Results: For an interquartile range (IQR) (3.9 dBA) higher daytime noise, a non-significant association with incident IHD was seen (Hazard ratio (HR): 1.015, 95% Confidence Interval (CI): 0.989-1.042), fully adjusted. Statistically significant associations and interaction terms were seen in obese individuals (HR: 1.099, 95%CI: 1.029-1.174), and current-smokers (HR: 1.054, 95%CI: 1.007-1.103). No associations were found for ischemic or hemorrhagic stroke. Conclusions: Our study strengthens the evidence base for an effect of road traffic noise on incident IHD, whilst the association with incident stroke remains unclear.
AU - Cai,Y
AU - Hodgson,S
AU - Blangiardo,M
AU - Gulliver,J
AU - Morley,D
AU - Vienneau,D
AU - de,Hoogh K
AU - Key,T
AU - Hveem,K
AU - Elliott,P
AU - Hansell,A
PY - 2017///
TI - Road traffic noise and incident cardiovascular disease: a joint analysis of HUNT, EPIC-Oxford and UK Biobank
T2 - ICBEN 2017 Proceedings
UR -
ER -