Imperial College London
Alternate

ProfessorMarkJohnson

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

Clinical Chair in Obstetrics
 
 
 
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Contact

 

+44 (0)20 3315 7887mark.johnson

 
 
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Location

 

H3.35Chelsea and Westminster HospitalChelsea and Westminster Campus

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Summary

 

Publications

Citation

BibTex format

@article{Lei:2015:10.1016/j.gdata.2015.09.008,
author = {Lei, K and Sooranna, SR and Johnson, MR},
doi = {10.1016/j.gdata.2015.09.008},
journal = {Genomics Data},
pages = {182--183},
title = {Expression data from primary culture human myometrial cells},
url = {http://dx.doi.org/10.1016/j.gdata.2015.09.008},
volume = {6},
year = {2015}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Inflammation plays a central role in many human diseases. Human parturition also resembles an inflammatory reaction, where progesterone (P4) and progesterone receptors (PRs) have already been demonstrated to suppress contraction-associated gene expression. In our previous studies, we have found that the progesterone actions, including progesterone-induced gene expression and progesterone's anti-inflammatory effect, are mediated by PR, GR or both. In this study, we used microarrays (GSE68171) to find P4 and IL-1β responsive genes and IL-1β responsive genes which were repressed by P4. These data may provide a broader view of gene networks and cellular functions regulated by P4 and IL-1β in human myometrial cells. These data will also help us understand the role of PR and GR in human parturition.
AU  - Lei,K
AU  - Sooranna,SR
AU  - Johnson,MR
DO  - 10.1016/j.gdata.2015.09.008
EP  - 183
PY  - 2015///
SN  - 2213-5960
SP  - 182
TI  - Expression data from primary culture human myometrial cells
T2  - Genomics Data
UR  - http://dx.doi.org/10.1016/j.gdata.2015.09.008
UR  - http://hdl.handle.net/10044/1/39612
VL  - 6
ER  -
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