Imperial College London
Dr Neil Murphy

DrNeilMurphy

Faculty of Medicine, School of Public Health

Honorary Senior Research Fellow
 
 
 
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Contact

 

neil.murphy

 
 
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Location

 

Norfolk PlaceSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@misc{Watling:2023:10.1158/0008-5472.23522246.v1,
author = {Watling, CZ and Kelly, RK and Murphy, N and Gunter, M and Piernas, C and Bradbury, KE and Schmidt, JA and Key, TJ and Perez-Cornago, A},
doi = {10.1158/0008-5472.23522246.v1},
title = {Figure 4 from Prospective Analysis Reveals Associations between Carbohydrate Intakes, Genetic Predictors of Short-Chain Fatty Acid Synthesis, and Colorectal Cancer Risk},
type = {Other},
url = {http://dx.doi.org/10.1158/0008-5472.23522246.v1},
year = {2023}
}
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RIS format (EndNote, RefMan)

TY  - GEN
AB  - <jats:p><p>Multivariable-adjusted hazard ratios (95% CI) for intake of fiber from breads and cereals from the touchscreen questionnaire and colorectal cancer risk by genetically predicted host short-chain fatty acid production for butyrate (<b>A</b>) and propionate (<i>n</i> = 343,621; <b>B</b>). Models stratified for sex and age at recruitment, and further adjusted for region, first 10 principal components, height, physical activity, Townsend deprivation index, education, employment, smoking, alcohol consumption measured at recruitment, diabetes status, nonsteroidal anti-inflammatory drug use, body mass index, processed and red meat intake, and female-specific covariates: menopausal hormone therapy use and menopausal status. Analyses are restricted to white British participants. χ<sup>2</sup> and <i>P</i> value represents improvement of fit obtained from likelihood ratio tests for including an interaction term between butyrate or propionate polygenic score and fiber from breads and cereals (modeled as a 5 gram/day increment) into the model. g/day, grams per day; <i>N</i>, number of participants; Q, quintile; ref, reference group.</p></jats:p>
AU  - Watling,CZ
AU  - Kelly,RK
AU  - Murphy,N
AU  - Gunter,M
AU  - Piernas,C
AU  - Bradbury,KE
AU  - Schmidt,JA
AU  - Key,TJ
AU  - Perez-Cornago,A
DO  - 10.1158/0008-5472.23522246.v1
PY  - 2023///
TI  - Figure 4 from Prospective Analysis Reveals Associations between Carbohydrate Intakes, Genetic Predictors of Short-Chain Fatty Acid Synthesis, and Colorectal Cancer Risk
UR  - http://dx.doi.org/10.1158/0008-5472.23522246.v1
ER  -
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