Imperial College London


Faculty of MedicineNational Heart & Lung Institute

Visiting Professor







c/o Prof Kim FoxGuy Scadding BuildingRoyal Brompton Campus






BibTex format

author = {Albuquerque, FN and Bortnick, A and Iqbal, J and Ishibashi, Y and Stone, GW and Serruys, PW},
doi = {10.1002/ccd.26099},
journal = {Catheterization and Cardiovascular Interventions},
pages = {909--919},
title = {Dual antiplatelet therapy, drug-eluting stents and bioresorbable vascular scaffolds: Evolutionary perspectives},
url = {},
volume = {87},
year = {2015}

RIS format (EndNote, RefMan)

AB - Dual antiplatelet therapy reduces the risk of myocardial infarction, stent thrombosis, and cardiovascular mortality after percutaneous coronary intervention, but the optimal duration of therapy remains unclear. Stent thrombosis, one of the most feared complications of coronary intervention, is associated with high mortality and morbidity and is related in part to technical and patient-specific factors. Advances in device technology and better understanding of the pathophysiology of stent thrombosis have reduced the frequency of this devastating complication. Bioresorbable vascular scaffolds possess a number of advantageous features and are currently undergoing active investigation. Bioresorbable vascular scaffolds have been demonstrated to restore physiologic vasomotion, allow for late lumen enlargement, and upon full resorption remove the nidus for very late polymer reactions and resolve concerns of stent malapposition and side branch jailing. Based on the results from recent large-scale randomized trials, the optimal duration of dual antiplatelet therapy may depend on the choice of device type, as well as the individual patient risk of ischemic versus hemorrhagic complications.
AU - Albuquerque,FN
AU - Bortnick,A
AU - Iqbal,J
AU - Ishibashi,Y
AU - Stone,GW
AU - Serruys,PW
DO - 10.1002/ccd.26099
EP - 919
PY - 2015///
SN - 1522-726X
SP - 909
TI - Dual antiplatelet therapy, drug-eluting stents and bioresorbable vascular scaffolds: Evolutionary perspectives
T2 - Catheterization and Cardiovascular Interventions
UR -
VL - 87
ER -