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@article{Stagg:2015:10.1371/journal.pone.0142425,
author = {Stagg, HR and Brown, J and Ibraim, E and Riekstina, V and Viiklepp, P and Cirule, A and Cocei, H and Danilovits, M and Dravniece, G and Jackson, C and White, PJ},
doi = {10.1371/journal.pone.0142425},
journal = {PLOS One},
title = {Drug Susceptibility Patterns in MDR-TB Patients: Challenges for Future Regimen Design. A Cross-Sectional Study},
url = {http://dx.doi.org/10.1371/journal.pone.0142425},
volume = {10},
year = {2015}
}

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TY  - JOUR
AB  - Globally, there is substantial concern regarding the challenges of treating complex drugresistance patterns in multidrug resistant tuberculosis cases. Utilising data from three differentsettings (Estonia, Latvia, Romania) we sought to contrast drug susceptibility profiles formultidrug resistant tuberculosis cases, highlight the difficulties in designing universal regimen,and inform future regimen selection. Demographic and microbiological surveillancedata for multidrug resistant tuberculosis cases from 2004–13 were analysed. High levels ofadditional resistance to currently recommended second line drugs were seen in all settings,with extensive variability between countries. Accurate drug susceptibility testing and drugsusceptibility testing data are vital to inform the development of comprehensive, flexible,multidrug resistant tuberculosis guidance.
AU  - Stagg,HR
AU  - Brown,J
AU  - Ibraim,E
AU  - Riekstina,V
AU  - Viiklepp,P
AU  - Cirule,A
AU  - Cocei,H
AU  - Danilovits,M
AU  - Dravniece,G
AU  - Jackson,C
AU  - White,PJ
DO  - 10.1371/journal.pone.0142425
PY  - 2015///
SN  - 1932-6203
TI  - Drug Susceptibility Patterns in MDR-TB Patients: Challenges for Future Regimen Design. A Cross-Sectional Study
T2  - PLOS One
UR  - http://dx.doi.org/10.1371/journal.pone.0142425
UR  - http://hdl.handle.net/10044/1/30020
VL  - 10
ER  -

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