Imperial College London
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Dr Suzie Cro

Faculty of Medicine, School of Public Health

Senior Lecturer in Medical Statistics and Clinical Trials
 
 
 
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Contact

 

+44 (0)20 7594 1743s.cro

 
 
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Location

 

Stadium HouseWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Kelleher:2022:10.1002/14651858.CD013534.pub3,
author = {Kelleher, MM and Phillips, R and Brown, SJ and Cro, S and Cornelius, V and Carlsen, KCL and Skjerven, HO and Rehbinder, EM and Lowe, AJ and Dissanayake, E and Shimojo, N and Yonezawa, K and Ohya, Y and Yamamoto-Hanada, K and Morita, K and Axon, E and Cork, M and Cooke, A and Van, Vogt E and Schmitt, J and Weidinger, S and McClanahan, D and Simpson, E and Duley, L and Askie, LM and Williams, HC and Boyle, RJ},
doi = {10.1002/14651858.CD013534.pub3},
journal = {Cochrane Database of Systematic Reviews},
pages = {1--177},
title = {Skin care interventions in infants for preventing eczema and food allergy.},
url = {http://dx.doi.org/10.1002/14651858.CD013534.pub3},
volume = {11},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BACKGROUND: Eczema and food allergy are common health conditions that usually begin in early childhood and often occur in the same people. They can be associated with an impaired skin barrier in early infancy. It is unclear whether trying to prevent or reverse an impaired skin barrier soon after birth is effective for preventing eczema or food allergy. OBJECTIVES: Primary objective To assess the effects of skin care interventions such as emollients for primary prevention of eczema and food allergy in infants. Secondary objective To identify features of study populations such as age, hereditary risk, and adherence to interventions that are associated with the greatest treatment benefit or harm for both eczema and food allergy. SEARCH METHODS: We performed an updated search of the Cochrane Skin Specialised Register, CENTRAL, MEDLINE, and Embase in September 2021. We searched two trials registers in July 2021. We checked the reference lists of included studies and relevant systematic reviews, and scanned conference proceedings to identify further references to relevant randomised controlled trials (RCTs).  SELECTION CRITERIA: We included RCTs of skin care interventions that could potentially enhance skin barrier function, reduce dryness, or reduce subclinical inflammation in healthy term (> 37 weeks) infants (≤ 12 months) without pre-existing eczema, food allergy, or other skin condition. Eligible comparisons were standard care in the locality or no treatment. Types of skin care interventions could include moisturisers/emollients; bathing products; advice regarding reducing soap exposure and bathing frequency; and use of water softeners. No minimum follow-up was required. DATA COLLECTION AND ANALYSIS: This is a prospective individual participant data (IPD) meta-analysis. We used standard Cochrane methodological procedures, and primary analyses used the IPD dataset. Primary outcomes wer
AU  - Kelleher,MM
AU  - Phillips,R
AU  - Brown,SJ
AU  - Cro,S
AU  - Cornelius,V
AU  - Carlsen,KCL
AU  - Skjerven,HO
AU  - Rehbinder,EM
AU  - Lowe,AJ
AU  - Dissanayake,E
AU  - Shimojo,N
AU  - Yonezawa,K
AU  - Ohya,Y
AU  - Yamamoto-Hanada,K
AU  - Morita,K
AU  - Axon,E
AU  - Cork,M
AU  - Cooke,A
AU  - Van,Vogt E
AU  - Schmitt,J
AU  - Weidinger,S
AU  - McClanahan,D
AU  - Simpson,E
AU  - Duley,L
AU  - Askie,LM
AU  - Williams,HC
AU  - Boyle,RJ
DO  - 10.1002/14651858.CD013534.pub3
EP  - 177
PY  - 2022///
SN  - 1469-493X
SP  - 1
TI  - Skin care interventions in infants for preventing eczema and food allergy.
T2  - Cochrane Database of Systematic Reviews
UR  - http://dx.doi.org/10.1002/14651858.CD013534.pub3
UR  - https://www.ncbi.nlm.nih.gov/pubmed/36373988
UR  - https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD013534.pub3/full
UR  - http://hdl.handle.net/10044/1/103824
VL  - 11
ER  -
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