Imperial College London
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ProfessorStephenDurham

Faculty of Medicine, National Heart & Lung Institute

Professor of Allergy and Respiratory
 
 
 
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Contact

 

+44 (0)20 7351 8024s.durham

 
 
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Location

 

Fulham RoadRoyal Brompton Campus

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Summary

 

Publications

Citation

BibTex format

@article{DURHAM:1985:10.1111/j.1365-2222.1985.tb02290.x,
author = {DURHAM, SR and KAY, AB},
doi = {10.1111/j.1365-2222.1985.tb02290.x},
journal = {Clinical & Experimental Allergy},
pages = {411--418},
title = {Eosinophils, bronchial hyperreactivity and latephase asthmatic reactions},
url = {http://dx.doi.org/10.1111/j.1365-2222.1985.tb02290.x},
volume = {15},
year = {1985}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - We have measured airways reactivity (methacholine PC20) and blood eosinophils in eleven asthmatics with allergeninduced latephase reactions. Before challenge there was a significant (P<0.05) inverse correlation between blood eosinophils and the methacholine PC20. After allergen inhalation eosinophil counts were significantly (P<0.01) elevated at 24 hr. These increases in blood eosinophil counts were not observed in patients who developed single early responses. The magnitude of the changes in eosinophil counts (24 hr minus prechallenge values) also correlated with the baseline methacholine PC20 (P<0.01) in the latephase responders. These observations suggest that there may be a direct association between eosinophils and airway reactivity in subjects who develop latephase asthmatic reactions. Copyright © 1985, Wiley Blackwell. All rights reserved
AU  - DURHAM,SR
AU  - KAY,AB
DO  - 10.1111/j.1365-2222.1985.tb02290.x
EP  - 418
PY  - 1985///
SN  - 0954-7894
SP  - 411
TI  - Eosinophils, bronchial hyperreactivity and latephase asthmatic reactions
T2  - Clinical & Experimental Allergy
UR  - http://dx.doi.org/10.1111/j.1365-2222.1985.tb02290.x
VL  - 15
ER  -
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