Imperial College London
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ProfessorSanjayPrasad

Faculty of Medicine, National Heart & Lung Institute

Professor of Cardiomyopathy
 
 
 
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Contact

 

+44 (0)20 7352 8121s.prasad

 
 
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Location

 

CMR UnitRoyal BromptonRoyal Brompton Campus

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Summary

 

Publications

Citation

BibTex format

@article{Maceira:2016:10.1186/s12968-016-0284-8,
author = {Maceira, AM and Cosin-Sales, J and Prasad, SK and Pennell, DJ},
doi = {10.1186/s12968-016-0284-8},
journal = {Journal of Cardiovascular Magnetic Resonance},
title = {Characterization of left and right atrial function in healthy volunteers by cardiovascular magnetic resonance.},
url = {http://dx.doi.org/10.1186/s12968-016-0284-8},
volume = {18},
year = {2016}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BACKGROUND: Left and right atrial function show a different pattern in advanced age in order to maintain adequate ventricular filling. It has been shown that left atrial (LA) function has a prognostic value in a number of heart conditions. Cardiovascular magnetic resonance (CMR) provides high quality images of the left and right atria using high temporal resolution steady state free precession (SSFP) cine sequences. We used SSFP cines to characterize atrial function in healthy, normotensive, volunteers. METHODS: We measured maximum, preatrial contraction and minimum left and right atrial volumes in 120 healthy subjects after careful exclusion of cardiovascular abnormality (60 men, 60 women; 20 subjects per age decile from 20 to 80 years). Data were generated from 3-dimensional modeling, including tracking of the atrioventricular ring motion and time-volume curves analysis. With those measurements, all the usual parameters for left and right atrial function were calculated. RESULTS: Gender had significant influence on some parameters of left and right atrial conduit and booster pump function. Age significantly influenced the majority of parameters of both left and right atrial function, with typically lower reservoir and conduit functions and higher booster pump function, both in males and females belonging to older age groups. CMR normal ranges were modelled for clinical use with normalization, where appropriate, for body surface area and gender, displaying parameters with respect to age. CONCLUSIONS: CMR normal reference ranges for components of left and right atrial function are provided for males and females for a wide age range.
AU  - Maceira,AM
AU  - Cosin-Sales,J
AU  - Prasad,SK
AU  - Pennell,DJ
DO  - 10.1186/s12968-016-0284-8
PY  - 2016///
SN  - 1532-429X
TI  - Characterization of left and right atrial function in healthy volunteers by cardiovascular magnetic resonance.
T2  - Journal of Cardiovascular Magnetic Resonance
UR  - http://dx.doi.org/10.1186/s12968-016-0284-8
UR  - http://hdl.handle.net/10044/1/41505
VL  - 18
ER  -
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