ProfessorSimonThom

Chapman N, Mayet J, Ozkor M, Foale R, Thom S, Poulter Net al., 2000, Ethnic and gender differences in electrocardiographic QT length and QT dispersion in hypertensive subjects, JOURNAL OF HUMAN HYPERTENSION, Vol: 14, Pages: 403-405, ISSN: 0950-9240

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• Citations: 17

Barratt DC, Ariff BB, Davies AH, Hughes AD, Thom SAM, Humphries KNNet al., 2000, A system for three-dimensional vascular ultrasound imaging, JOURNAL OF PHYSIOLOGY-LONDON, Vol: 525, Pages: 4P-5P, ISSN: 0022-3751

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Xu XY, Zhao SZ, Long Q, Ariff B, Hughes AD, Thom SAet al., 2000, 3D reconstruction of flow patterns and shear stress in human arteries, JOURNAL OF PHYSIOLOGY-LONDON, Vol: 525, Pages: 4P-4P, ISSN: 0022-3751

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Chapman JN, Haimes G, Stanton AV, Thom SA, Hughes ADet al., 2000, Acute effects of oxygen and carbon dioxide on retinal arteriolar network geometry: differences between hypertensives and normotensives, JOURNAL OF PHYSIOLOGY-LONDON, Vol: 525, Pages: 20P-21P, ISSN: 0022-3751

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Ariff B, Foale RA, Mayet J, 2000, Stress echocardiography for the diagnosis of ischaemia in hypertensives, JOURNAL OF HUMAN HYPERTENSION, Vol: 14, Pages: 399-401, ISSN: 0950-9240

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• Citations: 4

Guzzetti S, Mayet J, Shahi M, Mezzetti S, Foale RA, Sever PS, Poulter NR, Porta A, Malliani A, Thom SAMet al., 2000, Absence of sympathetic overactivity in Afro-Caribbean hypertensive subjects studied by heart rate variability, JOURNAL OF HUMAN HYPERTENSION, Vol: 14, Pages: 337-342, ISSN: 0950-9240

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• Citations: 20

Long Q, Xu XY, Ariff B, Thom SA, Hughes AD, Stanton AVet al., 2000, Reconstruction of blood flow patterns in a human carotid bifurcation: A combined CFD and MRI study, JOURNAL OF MAGNETIC RESONANCE IMAGING, Vol: 11, Pages: 299-311, ISSN: 1053-1807

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• Citations: 129

Barratt DC, Ariff BB, Davies AH, Hughes AD, Thom SAMG, Humphries KNNet al., 2000, Accuracy of three-dimensional ultrasound reconstruction in a clinical environment, Ultrasound in Medicine and Biology, Vol: 26, ISSN: 0301-5629

The objective of this study was to assess the accuracy of three-dimensional (3D) reconstructions obtained in a clinical setting using a freehand 3D ultrasound imaging system based on an electromagnetic position and orientation measurement device. An ultrasound phantom comprising a 4×2 matrix of non-magnetic pins fixed 25 mm apart in plastic was immersed in 9% glycerol solution and scanned five times using a 3D ultrasound imaging system on a couch used for clinical scanning. Inter-pin distances were then calculated from the 3D reconstructions. 140 inter-pin distance measurements were computed. The root-mean-square error over all five scans was 1.01 mm, with a mean absolute percentage error of 1.85±1.22% (Mean±Standard deviation), and a range of 0.05-3.43%. The results of this phantom study show that accurate measurement of distances from 3D reconstructions is achievable in a clinical environment using a 3D ultrasound imaging system which incorporates an electromagnetic tracking device.

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• Citations: 1

Barratt DC, Ariff BB, Davies AH, Hughes AD, Thom SAMG, Humphries KNet al., 2000, Quantitative measures of carotid disease from three-dimensional ultrasound images, Ultrasound in Medicine and Biology, Vol: 26, ISSN: 0301-5629

The objective of this study was to develop accurate, robust, automatic methods for quantifying carotid disease using measures derived from three-dimensional (3D) ultrasound reconstructions. A surface model of the carotid vessel wall and atherosclerotic disease was reconstructed from transverse colour Duplex images together with 3D position and orientation data for each slice. The resulting geometric model was used to estimate a series of new measures: in particular, plaque volume, volumetric stenosis (vessel volume/lumen volume), and transverse area stenosis as a function of length along the vessel is computed and compared with standard two-dimensional (2D) B-mode and velocity measures of stenosis. Efficient computer algorithms to compute the various 3D plaque measures have been implemented which highlight some of the inadequacies of conventional, 2D measures of carotid disease. In conclusion, 3D measures of carotid plaques potentially provide a more reliable and accurate index of severity of disease than standard 2D measures.

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Zambanini A, Cunningham SL, Ariff B, Parker KH, Thom, SAMG, Hughes ADet al., 2000, Wave intensity analysis: A novel method for haemodynamic assessment in man, Journal of Hypertension, Vol: 18, Pages: S61-S61

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Martinez-Perez ME, Hughes AD, Stanton AV, Thom SA, Chapman N, Bharath AA, Parker KHet al., 2000, Geometrical and morphological analysis of vascular branches from fundus retinal images, MICCAI, Lecture Notes In Computer Science, Pages: 756-765

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Cunningham SL, Zambanini A, Mayet J, Foale RA, Parker KH, Thom, SAMG, Hughes ADet al., 2000, Wave intensity analysis: Reproducibility of a novel assessment of haemodynamics in normal subjects, Hypertension, Vol: 36, Pages: 669-669

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Coombes JE, Hughes AD, Thom SA, 1999, Intravascular pressure-evoked changes in intracellular calcium [Ca<SUP>2+</SUP>], and tone in rat mesenteric and rabbit cerebral arteries <i>in vitro</i>, JOURNAL OF HUMAN HYPERTENSION, Vol: 13, Pages: 855-858, ISSN: 0950-9240

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• Citations: 7

Chapman JN, Mayet J, Foale RA, Thom SAet al., 1999, Intraventricular dispersion of E wave velocity: an alternative measure of left ventricular diastolic function in hypertensive patients?, JOURNAL OF HUMAN HYPERTENSION, Vol: 13, Pages: 867-869, ISSN: 0950-9240

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• Citations: 7

Wimalasundera R, Regan L, Thom S, Hughes Aet al., 1999, Effects of TNF-α on relaxation of rat mesenteric vessels:: a role in pre-eclampsia?, HYPERTENSION, Vol: 34, Pages: 701-701, ISSN: 0194-911X

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Starmans-Kool M, Stanton A, Zhao S, Xu Y, Hughes A, Thom S, Struijker Het al., 1999, Carotid haemodynamics and the effects of salt, HYPERTENSION, Vol: 34, Pages: 706-706, ISSN: 0194-911X

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Chapman N, Haimes G, Stanton A, Thom S, Hughes Aet al., 1999, Acute effects of oxygen and carbon dioxide on vascular network geometry in hypertensives and normotensives, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 704-704, ISSN: 0194-911X

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Chapman JN, Mayet J, Chang CL, Foale RA, Thom SAM, Poulter NRet al., 1999, Ethnic differences in the identification of left ventricular hypertrophy in the hypertensive patient, AMERICAN JOURNAL OF HYPERTENSION, Vol: 12, Pages: 437-442, ISSN: 0895-7061

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• Citations: 55

Zhao SZ, Xu XY, Collins MW, Stanton AV, Hughes AD, Thom SAet al., 1999, Flow in carotid bifurcations: effect of the superior thyroid artery, MEDICAL ENGINEERING & PHYSICS, Vol: 21, Pages: 207-214, ISSN: 1350-4533

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• Citations: 22

Mayet J, Kanagaratnam P, Shahi M, Senior R, Doherty M, Poulter NR, Sever PS, Handler CE, Thom SAM, Foale RAet al., 1999, QT dispersion in athletic left ventricular hypertrophy, AMERICAN HEART JOURNAL, Vol: 137, Pages: 678-681, ISSN: 0002-8703

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• Citations: 26

Mayet J, Thom SAM, 1999, Left ventricular hypertrophy: a population perspective, EUROPEAN HEART JOURNAL, Vol: 20, Pages: 400-401, ISSN: 0195-668X

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• Citations: 2

Zhao SZ, Xu XY, Collins MW, Stanton AV, Hughes AD, Thom SAet al., 1999, The convergence technique in numerical solutions of coupled fluid-wall problems, Conference on Cardiovascular Flow Modelling and Measurement with Application to Clinical Medicine, Publisher: OXFORD UNIVERSITY PRESS, Pages: 125-134

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Martinez-Perez ME, Hughes AD, Stanton AV, Thom SA, Bharath AA, Parker KHet al., 1999, Retinal blood vessel segmentation by means of scale-space analysis and region growing, Proceedings of the Second International Conference on Medical Image Computing and Computer Assisted Intervention, Cambridge

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Stanton AV, Chapman JN, Sever PS, Poulter NR, Hughes AD, Thom SAet al., 1998, Greater regression of early atherosclerosis by calcium channel blockade than by angiotensin converting enzyme inhibition, HYPERTENSION, Vol: 32, Pages: 795-795, ISSN: 0194-911X

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• Citations: 1

Chester AH, Borland JAA, Morrison KJM, Amrani M, Thom SM, Yacoub MHet al., 1998, Reactivity of small intramyocardial arteries from atherosclerotic and non-atherosclerotic human hearts, JOURNAL OF VASCULAR RESEARCH, Vol: 35, Pages: 170-178, ISSN: 1018-1172

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• Citations: 2

Thom SA, Gao X, Stanton AV, Chapman JN, Bharath A, Hughes ADet al., 1998, A computer system for automated retinal microvascular architecture quantification, JOURNAL OF HYPERTENSION, Vol: 16, Pages: S106-S106, ISSN: 0263-6352

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• Citations: 1

Stanton AV, Chapman JN, Sever PS, Poulter NR, Hughes AD, Thom SAet al., 1998, Greater regression of early atherosclerosis by calcium channel blockade than by angiotensin converting enzyme inhibition, JOURNAL OF HYPERTENSION, Vol: 16, Pages: S25-S25, ISSN: 0263-6352

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• Citations: 1

Chapman N, Mayet J, Chang L, Foale R, Thom S, Poulter Net al., 1998, Ethnic differences in ECG detection of left ventricular hypertrophy, JOURNAL OF HYPERTENSION, Vol: 16, Pages: S199-S199, ISSN: 0263-6352

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Mayet J, Chapman N, Li CKC, Shahi M, Poulter NR, Sever PS, Foale RA, Thom SAMet al., 1998, Ethnic differences in the hypertensive heart and 24-hour blood pressure profile, HYPERTENSION, Vol: 31, Pages: 1190-1194, ISSN: 0194-911X

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• Citations: 48

Chapman N, Mohamudally A, Cerutti A, Stanton A, Sayer AA, Cooper C, Barker D, Rauf A, Evans J, Wormald R, Sever P, Hughes A, Thom Set al., 1997, Retinal vascular network architecture in low-birth-weight men, JOURNAL OF HYPERTENSION, Vol: 15, Pages: 1449-1453, ISSN: 0263-6352

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• Citations: 79