Imperial College London
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Simon Erridge

Faculty of Medicine, Department of Surgery & Cancer

Research Postgraduate
 
 
 
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simon.erridge12

 
 
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Location

 

Block B Hammersmith HospitalHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Erridge:2021:10.1007/s11695-020-05196-7,
author = {Erridge, S and Moussa, O and McIntyre, C and Hariri, A and Tolley, N and Kotecha, B and Purkayastha, S},
doi = {10.1007/s11695-020-05196-7},
journal = {Obesity Surgery},
pages = {1986--1993},
title = {Obstructive sleep apnea in obese patients: a UK population analysis},
url = {http://dx.doi.org/10.1007/s11695-020-05196-7},
volume = {31},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BackgroundObstructive sleep apnea (OSA) is an increasingly common disorder associated with increased cardiovascular disease, mortality, reduced productivity, and an increased risk of road traffic accidents. A significant proportion of patients with OSA in the UK are undiagnosed. This study aims to identify risk factors for OSA in an obese cohort.MethodA population-based study was conducted of obese patients (BMI ≥ 30 kg/m2) from the Clinical Practice Research Datalink (CPRD). A logistic regression model was used to calculate odds ratios (ORs) for developing OSA according to other clinicopathological characteristics. Multivariate analysis was conducted of individual factors that affect the propensity to develop OSA. Statistical significance was defined as p < 0.050.ResultsFrom 276,600 obese patients identified during a data extraction of the CPRD in July 2017, the prevalence of OSA was 5.4%. The following risk factors were found to be independently associated with increased likelihood of OSA: male sex (OR = 3.273; p < 0.001), BMI class II (OR = 1.640; p < 0.001), BMI class III (OR = 3.768; p < 0.001), smoking (OR = 1.179; p < 0.001), COPD (OR = 1.722; p < 0.001), GERD (OR = 1.557; p < 0.001), hypothyroidism (OR = 1.311; p < 0.001), acromegaly (OR = 3.543; p < 0.001), and benzodiazepine use (OR = 1.492; p < 0.001). Bariatric surgery was associated with reduced risk of OSA amongst this obese population (OR = 0.260; p < 0.001).ConclusionsIn obese patients, there are numerous comorbidities that are associated with increased likelihood of OSA. These factors can help prompt clinicians to identify undiagnosed OSA. Bariatric surgery appears to be prot
AU  - Erridge,S
AU  - Moussa,O
AU  - McIntyre,C
AU  - Hariri,A
AU  - Tolley,N
AU  - Kotecha,B
AU  - Purkayastha,S
DO  - 10.1007/s11695-020-05196-7
EP  - 1993
PY  - 2021///
SN  - 0960-8923
SP  - 1986
TI  - Obstructive sleep apnea in obese patients: a UK population analysis
T2  - Obesity Surgery
UR  - http://dx.doi.org/10.1007/s11695-020-05196-7
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000606406000004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://link.springer.com/article/10.1007%2Fs11695-020-05196-7
UR  - http://hdl.handle.net/10044/1/91651
VL  - 31
ER  -
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