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Human PKD1 MPPAAPARLALALGLGLWLGALAGGPGRGCGPCEPPCLCGPAPGAACRV
Mouse PKD1 MPPGAPALLALALGLGLWLGALAGDPGRGCGPCPLPCFCGPAPDAACRV
Human PK1L2 MSAVGLVLLVLALRLRATTVKPEEGSFCSNSQVAFRDACYEFVPLGRTF
Mouse Pk1L2 M--AGLVFLGLALSSGATVAKSEGGSLCSRSQVFFRDACYEFVPLEHTF
Human PK1L3 MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH
Mouse PK1L3 MLLQRRSWLWLYIRIGVILGDILGRKPSIREQHGGNSCYQLNRLFCDFQEADNYCHAQRG
Human PKD1 NCSGRGLRTLGPALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSG
Mouse PKD1 NCSGRWLQTLGPSLRIPADATALDLSHNLLQTLDIGLLVNLSALVELDLSNNRISTLEEGVFANLFNLSEINLSG
Human PKD1 NPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGC
Mouse PKD1 NPFECNCGLAWLPRWAKEHQVHVVQSEATTCRGPIPLAGQPLLSIPLLDNAC
Human PKD1 WSC GEEYVACLPDNSSGTVAAVSFSAAHEGLLQPEACSAFCFSTGQGLAALSEQGWCLCGAAQP
Mouse PKD1 WSC GEEYVACLPDNSSGAVAAVPFYFAHEGPLETEACSAFCFSAGEGLAALSEQNQCLCGAGQA
Human PKD1 Link SSASFACLSLCSGPPPPPAPTCRGPTLLQHVFPASPGATLVGPH
Mouse PKD1 Link SNSSAACSSWCSSISLSLNSACGGPTLLQHTFPASPGATLVGPH
Human PKD1 GPLASGQLAAFHIAAPLPVTATRWDFGDGSAEVDAAGPAASHRYVLPGRYHVTAVLALGAGSALLGTDVQVE
Mouse PKD1 GPLASGQPADFHITSSLPISSTRWNFGDGSPEVDMASPAATHFYVLPGSYHMTVVLALGAGSALLETEVQVE
Human PKD1 AAPAALELVCPSSVQSDESLDLSIQNRGGSGLEAAYSIVALGEEPARAVHP
Mouse PKD1 ATPTVLELVCPSFVHSNESLELGIRHRGGSALEVTYSILALDKEPAQVVHP
Human PKD1 LCPSDTEIFPGNGHCYRLVVEKAAWLQAQEQCQAWAGAALAMVDSPAVQRFLVSRVTRCLDVWIGFSTVQGVE
Mouse PKD1 LCPLDTEIFPGNGHCYRLVAEKAPWLQAQEQCRTWAGAALAMVDSPAIQHFLVSKVTRSLDVWIGFSSVEGTE
Human PKD1 VGPAPQGEAFSLESCQNWLPGEPHPATAEHCVRLGPTGWCNTDLCSAPHSYVCE
Mouse PKD1 -GLDPRGEAFSLESCQNWLPGEPHPATAEHCVRLGPAGQCNTDLCSAPHSYVCE
Human PK1L2 FCSNSQVAFRDACYEFVPLGRTFRDAQSWCEGQGGHLVFIQDEGTQWFLQKHISQDREWWIGLTWNLARN
Mouse PK1L2 LCSRSQVFFRDACYEFVPLEHTFPGAQGWCEGHGGHLAFIPDEDTQQFLQRHITQDREWWIGLTGGSGHN
Human PK1L2 GTTEGPGTWLDTSNVTYSNWHGGQAAAAPDTCGHIGRGPSSEWVTSD-CAQTFAFMCE
Mouse PK1L2 GTVGGSGTWLDTSNVNYSNWQEGQATPAPGSCGYIGSGPSSQWAALEDCTQTFAFVCE
Human PK1L3 GSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAHIWNKEVQDLIRDYLEEGKKWWIGQNVMPLKK
Mouse PK1L3 GRKPSIREQHGGNSCYQLNRLFCDFQEADNYCHAQRGRLAHTWNPKLRGFLKSFLNEETVWWVRGNLTLPGS
Human PK1L3 HQDNKYPADVAANGPPKPLSCTYLSRNFIRISSKGDKCLLKYYFICQ
Mouse PK1L3 HPGINQTGGDDVLRNQKPGECPSVVTHSNAVFSRWNLCIEKHHFICQ
Human PKD1 LQPGGPVQDAENLLVGAPSGDLQGPLTPLAQQDGLSAPHEPVEVMVFPGLRLSREAFLTTAEFGTQELRRPAQLRLQVYRLLSTAGTPENGSEPESRSPDNR
Mouse PKD1 LRPGGPVWDTENFVMGMSGGGLSGPLHPLAQQETVQGPLRPVEVMVFPGLSPSREAFLTAAEFSTQKLEEPAQMRLQVYRPSGGAAAVPEGSSE----PDNR
Human PKD1 TQLAPACMPGGRWCPGANICLPLDASCHPQACANGCTSGPGLPGAPYALWREFLFSVPAGPPAQYSVTLHGQDVLMLPGDLVGLQHDAGPGALLHCSPAPGH
Mouse PKD1 TEPAPKCVPEELWCPGANVCIPFDASCNSHVCINGSVSRLGLSRASYTLWKEFFFSVPAGPPTQYLVTLHSQDVPMLPGDLIGLQHDAGPGTLLQCPLASSC
Human PKD1 PGPRAPYLSANASSWLPHLPAQLEGTWACPACALRLLAATEQLTVLLGLRPNPGLRLPGRYEVRAEVGNGVSRHNLSCSFDVVSPVAGLRVIYPAPRDGRLY
Mouse PKD1 PG-QALYLSTNASDWMTNLPVHLEEAWAGPVCSLQLLLVTEQLTPLLGLGPNPGLQHPGHYEVRATVGNSVSRQNLSCSFSVVSPIAGLRVIHPIPLDGHIY
Human PKD1 VPTNGSALVLQVDSGANATATARWPG
Mouse PKD1 VPTNGSVLVLQVDSGANATATAQWFG
Human PKD1 (2) GSVSARFENVCPALVATFVPGCPWETNDTLFSV--------------------------VALPWLSEGEHVVDVVVENSASRANLSLRVTAEEPICGLRATPSPEA
Mouse PKD1 (2) GNISAPFEDACPPDVDFLKQDCTEEANGTLFSV--------------------------LMLPRLKEGDHTVEIVAQNGASQANLSLRVTAEEPICGLRAVPSPEA
Human PKD1 (3) RVLQGVLVRYSPVVEAGSDMVFRWTINDKQSLTFQNVV---------------------FNVIYQSAAVFKLSLTASNHVSNVTVNYNVTVERMNRMQGLQVSTVPAVL
Mouse PKD1 (3) RVLQGILVRYSPMVEAGSDVAFRWTIDDKQSLTFHNTV---------------------FNVIYQSAAIFKLSLTASNHVSNITVNYNVTVERMNKMHGLWVSAVPTVL
Human PKD1 (4) SPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPPYNESFPVPDPSVAQVLVEHNVMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGV
Mouse PKD1 (4) PPNATLALTGGVLVDSAVEVAFLWNFGDGEQVLRQFKPPYDESFQVPDPTVAQVLVEHNTTHIYTTPGEYNLTVLVSNTYENLTQQVTVSVRTVLPNVAIGMSSNV
Human PKD1 (5) LVAGRPVTFYPHPLPSPGGVLYTWDFGDGSPVLTQSQPA--------------------ANHTYASRGTYHVRLEVNNTVSGAAAQADVRVFEELRGLSVDM
Mouse PKD1 (5) LVAGQPITFSPYPLPSTDGVLYTWDFGDGSPVLIQSQPV--------------------LNHTYSMTGTYRITLEVNNTVSSVTAHADIRVFQELHGLTVYL
Human PKD1 (6) SLAVEQGAPVVVSAAVQTGDNITWTFDMGDGTVLSGPEAT-------------------VEHVYLRAQNCTVTVGAASPAGHLARSLHVLVFVLEVLRVEPAAC
Mouse PKD1 (6) SPSVEQGAPMVVSASVESGDNITWTFDMGDGTVFTGPEAT-------------------VQHVYLRAQNFTVTVEAANPAGHLSQSLHVQVFVLEVLRIEPSTC
Human PKD1 (7) IPTQPDARLTAYVTGNPAHYLFDWTFGDGSSNTTVRGCPT-------------------VTHNFTRSGTFPLALVLSSRVNRAHYFTSICVEPEVGNVTLQPERQ
Mouse PKD1 (7) IPTQPSAQLMAHVTGDPVHYLFDWTFGDGSSNVTVHGHPS-------------------VTHNFTRSGIFPLALVLSSHVNKAHYFTSICVEPEIRNITLQPERQ
Human PKD1 (8) FVQLGDEAWLVACAWPPFPYRYTWDFGTEEAAPTRARGPE-------------------VTFIYRDPGSYLVTVTASNNISAANDSALVEVQEPVLVTSIKVNGS
Mouse PKD1 (8) FVKLGDEARLVAYSWPPFPYRYTWDFGTEDTTHTQTGGSE-------------------VKFIYREPGSYLVIVTVSNNISSTNDSAFVEVQEPVLVTGIRINGS
Human PKD1 (9) LGLELQQPYLFSAVGRGRPASYLWDLGDGGWLEGPE-----------------------VTHAYNSTGDFTVRVAGWNEVSRSEAWLNVTVKRRVRGLVVNASRT
Mouse PKD1 (9) HVLELQQPYLLSAMGSGSPATYLWELGDGSQSEGPE-----------------------VTHIYSSTGDFTVRVSGWNEVSRSEAQLNITVKQRVRGLTINASRT
Human PKD1 (10) VVPLNGSVSFSTSLEAGSDVRYSWVLCDRCTPIPGGPT---------------------ISYTFRSVGTFNIIVTAENEVGSAQDSIFVYVLQLIEGLQVVGGGR--
Mouse PKD1 (10) VVPLNGSVSFSTLLEVGSDVHYSWVLCDRCTPIPGGPT---------------------ISYTFRSVGTFNIIVTAENEVGSAQDSIFIYVLQFIEGLQVVGGDNGC
Human PKD1 (11) YFPTNHTVQLQAVVRDGTNVSYSWTAWRDRGPALAGSGKG-------------------FSLTVLEAGTYHVQLRATNMLGSAWADCTMDFVEPVGWLMVAASPN
Mouse PKD1 (11) CFPTNYTLQLQAAVRDGTNISYSWTAQQEGSLITLFGSGKC------------------FSLTALKASTYYVHLRATNMLGSAAANRTIDFVEPVESLILSASPN
Human PKD1 (12) PAAVNTSVTLSAELAGGSGVVYTWSLEEGLSWETSEPF---------------------TTHSFPTPGLHLVTMTAGNPLGSANATVEVDVQVPVSGLSIRASEPG
Mouse PKD1 (12) PAAVNMSLTLCAELAGGSGVVYTWYLEEGLSWKTSMPS---------------------TTHTFATPGLHLVRVTAENQLGSVNATVEVAIQVPVGGLSIRTSEPD
Human PKD1 (13) GSFVAAGSSVPFWGQLATGTNVSWCWAVPGGSSKRGPH---------------------VTMVFPDAGTFSIRLNASNAVSWVSATYNLTAEEPIVGLVLWASSK
Mouse PKD1 (13) SIFVAAGSTLPFWGQLAEGTNVTWCWTLPGGSKDSQYI---------------------AVR-FSTAGSFSLQLNASNAVSWVSAMYNLTVEEPIVNLMLWASSK
Human PKD1 (14) VVAPGQLVHFQILLAAGSAVTFRLQVGGANPEVLPGPR---------------------FSHSFPRVGDHVVSVRGKNHVSWAQAQVRIVVLEAVSGLQVPNCCEP
Mouse PKD1 (14) VVAPGQPVHFEILLAAGSALTFRLQVGGSVPEVLPSPH---------------------FSHSFFRVGDHLVNVQAENHVSHAQAQVRILVLEAVVGLQVPNCCEP
Human PKD1 (15) GIATGTERNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRD----------------VTYTPVAAGLLEIQVRAFNALGSENRTLVLEVQDAVQYVALQSGP
Mouse PKD1 (15) GMATGTEKNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRD----------------VTYTPVAAGLLEIHVRAFNELGGVNLTLMVEVQDIIQYVTLQSGR
Human PKD1 (16) CFTNRSAQFEAATSPSPRRVAYHWDFGDGSPGQDTDEPR--------------------AEHSYLRPGDYRVQVNASNLVSFFVAQATVTVQVLA
Mouse PKD1 (16) CFTNRSARFEAATSPSPRCVTYHWDFGDGTPVQKTEEFW--------------------ADHYYLRPGDYHVEVNATNLVSFFVAQATVTVQVLA
Human PKD1 CREPEVDVVLPLQVLMRRSQRNYLEAHVDLRDCVTYQTEYRWEVYRTASCQRPGRPARVALPGVDVSRPRLVLPRLALPVGHYCFVFVVSFGDTPLTQSIQANV
Mouse PKD1 CREPEVEVALPLQVLMRRSQRNYLEAHVDLRNCVSYQTEYRWEIYRTASCQRPGRMAQMVLPGVDVSRPQLVVPRLALPVGHYCFVFVVSFGDTPLARSIQANV
Human PKD1 TVAPERLVPIIEGGSYRVWSDTRDLVLDGSESYDPNLEDGDQTPLSFHWACVASTQREAGGCALNFGPRGSSTVTIPRERLAAGVEYTFSLTVWKAGRKEEATN
Mouse PKD1 TVAAERLVPIIEGGSYRVWSDTQDLVLDGSKSYDPNLEDGDQTPLNFHWACVASTQSETGGCVLNFGPRGSSVVTIPLERLEAGVEYTFNLIVWKAGRKEEATN
Human PKD1 QTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGRCLNCSSGSKRGRWAARTFSNKTLVLDETTTSTGSAGMRLVLRRGVLRDGEGYTFTLTVLGRSGEE
Mouse PKD1 QTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGHCHNCSRGYKQGCWAARTFSNKTLVLNETTTSTGSTGMNLVVRPGALRDGEGYIFTLTVLGHSGEE
Human PKD1 EGCASIRLSPNRPPLGGSCRLFPLGAVHALTTKVHFECTGWHDAEDAGAPLVYALLLRRCRQGHCEEFCVYKGSLSSYGAVLPPGFRPHFEVGLAVVVQDQLGA
Mouse PKD1 EGCASIRLSPNRPPLGGSCRLFPLDSVRGLTTKVHFECTGWRDAEDGGAPLVYVLLLKRCRQSYCENFCIYKGSLSTYGAVLPPGFQPLFVVSLAVVVQDQLGA
Human PKD1 AVVALNRSLAITLPEPNGSATGLTVWLHGLTASVLPGLLRQADPQHVIEYSLALVTVLNEYERALDVAAEPKHERQHRAQIRKNITETLVSLRVHTVDDIQQIA
Mouse PKD1 AVVALNRSLTIVLPEPSGNPADLVPWLHSLTASVLPGLLKQADPQHVIEYSLALITVLNEYEQAPDVS-EPNVEQQLRAQMRKNITETLISLRVNTVDDIQQIT
Human PKD1 AALAQCMGPSRELVCRSCLKQTLHKLEAMMLILQAETTAGTVTPTAIGDSILNITGDLIHLASSDVRAPQPSELGAESPSRMVASQAYNLTSALMRILMRSRVL
Mouse PKD1 AALAQCMVSSRELMCRSCLKKMLQKLEGMMRILQAETTEGTLTPTTIADSILNITGDLIHLASLDMQGPQPLELGVEPPSLMVASKAYNLSSALMRILMRSRVL
Human PKD1 NEEPLTLAGEEIVAQGKRSDPRSLLCYGGAPGPGCHFSIPEAFSGALANLSDVVQLIFLVDSNP
Mouse PKD1 NEEPLTLAGEEIVALGKRSDPLSLLCYGKALGPSCHFSIPEAFSGALSNLSDVVQLIFLVDSNP
Human PK1L2 RHRLEIQATGNTTTSTISR---NITVHLVELLSGLQASWASDHLELGQDLLITISLAQGTPEELTFEVAGLNATFSHEQVSFGEPFGICRLAVPVEGTFLVTMLVR
Mouse PK1L2 RHHLKIQAVSNEGTGTASAPSGNFTVYFVEPLSGLRASWASDRVELGWDLVVNVSVARGTLEELTFEVAGLNANFSQEEESVGQSSGNYHVAVPAEGTFLVTVHVR
Human PK1L2 NAFSNLSLEIGNITITAPSGLQEPSGMNAEGKSKDKGDMEVYIQPGPYVDPFTTVTLGWPDNDKELRFQWSCGSCWALWSSCVERQLLRTDQRELVVPASCLP
Mouse PK1L2 NAFSELSLDIGNITVTASSSLQELSGINAEAKSGHKQDMKVFTEPELYVDPFTEVTLGWPDDDPGLNFHWSCGRCWAQWNACVGRQLLHTDQRLLVLHTFCLP
Human PK1L2 PPDSAVTLRLAVLRGQELENRAEQCLYVSAPWELRPRVSCERNCRPVNASKDILLRVTMGEDSPVAMFSWYLDNTPTEQAEPLLDACRLRGFWPRSLTLLQSN
Mouse PK1L2 PLNSAVTLHLAILRGQELEKETEQCLYVSAPLNLGPQISCEKNCRPVKADQDVLLTVTVGDETSVAVFSWYLDDTVPEEVEPLPAACRLRGFWPRSLTLLHSN
Human PK1L2 TSTLLLNSSFLQSRGEVIRIRATALTRHAYGEDTYVISTVPPREVPACTIAPEEGTVLTSFAIFCNASTALGPLEFCFCLESGSCLHCGPEPALPSVYLPLGE
Mouse PK1L2 SSVLLLNSSFLQTWGPVIPIRVTALTSHAYGEDTYMISMLPRPEVPACTIDPEEGSVLTSFTVSCSTPATLGPVEYCFCLPSGFCLHCGPEPALPAVYLPLGE
Human PK1L2 ENNDFVLTVVISATNRAGDTQQTQAMAKVALGDTCVEDVAFQAAVSEKIPTALQGEGGPEQLLQLAKAVSSMLNQEHESQGSGQSLSIDVRQKVREHVLGSLS
Mouse PK1L2 EKDGFVLPVVISVTNRAGDIEQTQVAVKVGHSYTGVEDVTFQEMVSERIATALHQESGREQLLLFAKAVSSELNSEVQSPGSGQ-LGMDIKRKVRELMLRSLS
Human PK1L2 AVTTGLEDVQRVQELAEVLREVTCRSKELTPSAQWEASLALQHASEALLTVSAKARPEDQRRQAATRDLFQAVGSVLEASLSNRPEEPAEASSSQIAT-VLRLL
Mouse PK1L2 VVTTGLQNMQRVQALAEVLREVTQRAEELTPAAQWEASCALQRATEALLVASTKVRPEDQRRQEATRAMFEAVGSVLEASLSHRSEEPMEANSSQVAYIVAQLL
Human PK1L2 RVMEHVQTTLLLGKLPGGLPAMLATPSISVYTNRIQPWSWQGSSLRPDAADSATFMLPAASSLSSLEGGQEPVDIKIMSFPKSP
Mouse PK1L2 RVIDHFQSALLLGTLPGGLPAILVTPSISVYTDRIQPRSWQGSSVHTAAADSVTFTLPAATFLCPMEDSQEPVDIRMMSFSQNP
Human PKD1 FPFGYISNYTVSTKVASMAFQTQAGAQIPIERLASERAITVKVPNNSDWAARGHRSSANSANSVVVQPQASVGAVVTLDSSNPAAGLHLQLNYTLLDGHYLSEE
Mouse PKD1 FPFGYISNYTVSTKVASMAFQTQTGTQIPIEQLAAERAITVKVPNNSDQAAQ---SSHNPVGSTIVQPQTSVSAVVTADNSNPQAGLHLRITYTVLNERYLSAE
Human PKD1 PEPYLAVYLHSEPRPNEHNCSASRRIRPESLQGADHRPYTFFISPGSRDPAGSYHLNLSSHFRWSALQVSVGL
Mouse PKD1 PEPYLAVYLHSVSQPNEYNCSASRRISLEVLEGADHRLYTFFIAPGTGTLDRSYYLNLTSHFHWSALEVSVGL
Human PKD1 YTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFGASLFVPPS
Mouse PKD1 YTSLCQYFSEEMMMWRTEGIVPLEETSPSQAVCLTRHLTAFGASLFVPPS
Human PK1L2 LSHCVFWDEVQETWDDSGCQVGPRTSPYQTHCLCNHLTFFGSTFLVMSNA
Mouse PK1L2 LAHCVFWDETQETWDDSGCQVGPRTTPSQTHCLCNHLTFFGSSFLVMPNA
Human PK1L3 VTQCYYWEIHNQTWSSAGCQVGPQSTILRTQCLCNHLTFFASDFFVVPRT
Mouse PK1L3 VTQCYFWDRYNRTWKSDGCQVGPKSTILKTQCLCDHLTFFSSDFFIVPRT
Human PKD1 HVRFVFPEPTADVNYIVMLTCAVCLVTYMVMAAILHKLDQLDASRGRAIPFCGQRGRFKYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRAFHRNSLDIFRIATPHSL
Mouse PKD1 HVQFIFPEPSASINYIVLLTCVICLVTYVVMAMILRKLDQLDVSRVRVIPFCGKGGRFKYEILVKTGWSRGSGTTAHVGIMLYGEDNRSGHRHLDGDRAFHRNSLDIFQIATPHSL
Human PKD1 GSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDAALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATCCVLLICLFL
Mouse PKD1 GSVWKIRVWHDNKGLSPAWFLQHIIVRDLQSARSTFFLVNDWLSVETEANGGLVEKEVLAANEAALWQFQRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRVQRVTCCVLLLCLFL
Human PKD1 GANAVWYGAVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPAGQQVLDIDSCLDSSVLDSSFLTFSGLHAEAFVGQMKSDLFLDDSKSLV
Mouse PKD1 AANAVWYGVVRDTTYSMGPVSSLISPGVDTVAIGLVSSVVVYPVYLAVLFLFRMSRSKVSGDQNPTPTGQQALDVDSYLDPSVLDSSLLTLSGL-TEAFAGQVKNDLFLEDAKSLV
Human PKD1 CWPSGEGTLSWPDLLSDPSIVGSNLRQLARGQAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGVSSPAPTQDTHMETDLLSSLSSTPGEKTETLALQRLGELGPPSPG
Mouse PKD1 CWPSSEGTLSWPDLLSDPSVVSSTLQRLTQGRPGCMLGSEEDGASLVSPSLPAKYLSASDEDLIHQVLADGANNLVPTQDTLLETDLLTSLSSVPGEKTETLILQTVGEERPASMG
Human PKD1 LNWEQPQAARLSRTGLVEGLRKRLLPAWCASLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFLGWEPLKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSA
Mouse PKD1 LSWEQSPVTRLSRTGLVEGFQKRLLPAWCAPLAHGLSLLLVAVAVAVSGWIGASFPPSVSVMWLLSSSSSFLASFLGWEPLKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSE
Human PKD1 RVPRVRPPHGFALFLAKEEARKVKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSEELWPWMAHVLLPYVHGNQSSPELGPPRLRQVRLQEA
Mouse PKD1 RVPRVRPPHGFALFLAKEEARKVKRLHDMLKRLLVYMLFLLVTLLANYGDASCHGHAYRLQSAIKQELDSQAFLAITRSDEFWPWMSHVFLPYVHGNQSSPELGPPRLRQVRLQEA
Human PKD1 LYPDPPGPRVHTCSAAGGFSTSDYDVGWESPHNGSGTWAYSAPDLLGAWSWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLHNWLDNRSRAVFLELTRYSPAVGLHAAVTLRLEF
Mouse PKD1 FCPDPSSSEHMCSAAGSLSTSDYGIGWQSVVQNGSETWAYSAPDLLGAWYWGYCAVYDSGGYIQELGLSLEESRARLGFLQLHNWLDSRSRAVFVELTRYSPAVGLHAAVTLRLEF
Human PKD1 PAAGRALAALSVRPFALRRLSAGLSLPLLTSVCLLLFAVHFAVAEARTWHREGRWRVLRLGAWARWLLVALTAATALVRLAQLGAADRQWTRFVRGRPRRFTSFDQVAQLSSAARG
Mouse PKD1 PVAGHALAAFSVRPFALRRLSTGLSLPLLTSVCLLLFALYFSMAEVQTWRKDGCACTARPDTWARCLLVILTAATGLVRLAQLGIADRQWTHCVQDHPHHFTSFDQVAQLGSVARG
Human PKD1 LAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGVTLGLVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESWHLSPLLCVGLWALRLWGALRLGAVI
Mouse PKD1 LAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELMGATLGLVLLGVAYAQMAILLISSGADTLYNMARAFLVLCPGARVPTLCPSESWYLSPLLCVGLWALRVWGALRLGAIL
Human PKD1 LRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLWMGLSKVKEFRHKVRFEGMEPLPSRSSRGSKVSPDVPPPSAGSDASHPSTSSSQLDGLSVSLGRLGTRCEPEPSRLQAVFEA
Mouse PKD1 LRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLWMGFSKVKEFRHKVRFEGMDPLPSRSSRGSKSSPVVLPPSSGSEASHPSTSSSQPDGPSASLSRSTLKLEPEPSRLHAVFES
Human PKD1 LLTQFDRLNQATEDVYQLEQQLHSLQGRRSSRAPAGSSRGPSPGLRPALPSRLARASRGVDLATGPSRTPLRAKNKVHPSST
Mouse PKD1 LLVQFDRLNQATEDVYQLEQQLQSLRGHGHNGPPSSPSPGCFPGSQPALPSRLSRASQGLDQTVGPNRVSLWPNNKVHPSST
Human PK1L2 TFLVMSNAINIHQTAELFATFEDNPVVVTTVGCLCVVYVLVVIWARRKDAQDQAKVKVTVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDTPVFER
Mouse PK1L2 SFLVMPNAIDVRQTAELFATFEDNPVVVTTVGCLCMLYVLVLIWARRKDIQDQAKVKVVVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTLTLYGSDGESEPHHLSDPDAAVFER
Human PK1L2 GAVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNSWLSINVGDCVLDKVFPVATEQDRKQFSHLFFMKTSAGFQDGHIWYSIFSRCARSSFTRVQR
Mouse PK1L2 GGVDVFLLSTLFPLGELQSLRLWHDNSGDRPSWYVSRVLVYDSVVDRKWYFLCNSWLSVDVGDCVLDKVFPVATEQDRKQFSHLFFTKTSTGFQDGHIWYSVFCSATRSSFTRVQR
Human PK1L2 VSCCFSLLLCTMLTSIMFWGVPKDPAEQKMDLGKIEFTWQEVMIGLESSILMFPINLLIVQIFQNTRPRVAKEQNTGKWDRGSPNLTPSPQPMEDGLLTPEAVTKDVSRIVSSLFK
Mouse PK1L2 VSCCFSMLLCTMLTSIMFWGVPKDPAEQKMDLGKIEFTWQEVMIGLESSILMFPINLLIVQIFRNTRPRLPMGKD-GRQKQGPPNLTPSAQPTEEGLLTPE--TGIQSLI-SSLFK
Human PK1L2 ALKVPSPALGWDSVNLMDINSLLALVEDVIYPQNTSGQVFWEEAKKREDPVTLTLGSSEMKEKSQCPKPKAARSGPWKDSAYRQCLYLQLEHVEQELRLVGPRGFSQPHSHAQALR
Mouse PK1L2 ALKVQPPASGWDSMNPVDINYLLTLMEDIICPESTEGPGFWEEAKGREDPITSTRGSVKPKENTWHPKPELAVRGLWKDSVYRRCLYLQLEHVERELQLLGPQGFLHHHSHAQALR
Human PK1L2 QLQTLKGGLGVQPGTWAPAHASALQVSKPPQGLPWWCILVGWLLVAATSGVAAFFTMLYGLHYGRASSLRWLISMAVSFVESMFVTQPLKVLGFAAFFALVLKRVDDEEDTVAPLP
Mouse PK1L2 QLHVLKGHLWGQPGTPALAYPSTSRVSKSPRGLPWWCVLVGWLLVATTSGVAAFFTMLYGLHYGRVSSLKWLISMAVSFVESVFITQPLKVLGFAAFFALVLKREDDEE-TLPLFP
Human PK1L2 GHLLGPDPYALFRARRNSSRDVYQPPLTAAIEKMKTTHLKEQKAFALIREILAYLGFLWMLLLVAYGQRDPSAYHLNRHLQHSFTRGFSGVLGFREFFKWANTTLVSNLYGHPPGF
Mouse PK1L2 GHLSSPGPGVLFRSRRHSSERAYQPPPMAAIEKMKTTRLKEQKAFALIREILAYLAFLWMLLLVAYGQRDPNAYHFHRHLERSFSQGFSPVLGFRGFFEWANTTLVKNLYGHHPGF
Human PK1L2 ITDGNSKLVGSAQIRQVRVQESSCPLAQQPQAYLNGCRAPYSLDAEDMADYGEGWNATTLSE-------WQYQSQDQRQGYPIWGKLTVYRGGGYVVPLGTDRQKHVKILRYLFDN
Mouse PK1L2 VTDGNSKLVGSAHIRQVRVRESSCAVAQQLQDSLDGCHGPYSLGIEDLVDYGEGWNASAYNNSNGFPQAWRYQSQSQRRGYPMWGKLTLYGGGGYVVPLGTDHQSASRILQYLFDN
Human PK1L2 TWLDALTRAVFVESTVYNANVNLFCIVTLTLETSALGTFFTHAALQSLRLYPFTDGWHPFVVAAELIYFLFLLYYMVVQGKRMSKETWGYFCSKWNLLELAIILASWSALAVFVKR
Mouse PK1L2 SWLDALTRAVFVEFTVYNANVNLFCTVTLTLETSGLGTFFSHVTLQSLRLYPFTDGWHPFVVAAELTYFLFLFYYMVVQGKLMRKQKWGYFCSKWNLLEVAIILASWSALVVFVKR
Human PK1L2 AVLAERDLQRCRNHREEGISFSETAAADAALGYIIAFLVLLSTVKLWHLLRLNPKMNMITAALRRAWGDISGFMIVILTMLLAYSIASNLIFGWKLRSYKTLFDAAETMVSLQLG
Mouse PK1L2 TILADRDLQRYREHRE-GISFSETAAADAALGYIIAFLVLLSTVKLWHLLRLNPKMNMITSALRRAWGDISGFVAVILIMLLAYSFASNLVFGWKLRSYKTLFDAAETMVSLQLG
Human PK1L2 IFNYEEVLDYSPVLGSFLIGSCIVFMTFVVLNLFISVILVAFSEEQKYYQLSEEGEIVDLLLMKILSFLGIKSKREEPGSSREQPGSLSQTRHSRPAQALPKD
Mouse PK1L2 IFNYEEVLDYSPILGSLLIGSCIVFMTFVVLNLFISVILVAFSEEQKSDQLSEEGEIADLLLVKILSFLGIRCKREETWSSSEQPELPPQALAPQPAQALSRV
Human PK1L3 TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARKKDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSE
Mouse PK1L3 TQCLCDHLTFFSSDFFIVPRTVDVENTIKLLLHVTNNPVGVSLLSSLLGFYILLAMWASRKDREDMQKVKVTVLADNDPSSASHYLIQVYTGYRRRAATTAKVVITLYGSE
Human PK1L3 GRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKF
Mouse PK1L3 GHSEPHHLCDPEKTVFERGALDVFLLSTGSWLGDLHGLRLWHDNSGDSPSWYVSQVIVSDMTTRKKWHFQCNCWLAVDLGNCERDRVFTPASRSELSSFRHLFSSTIVEKF
Human PK1L3 TQDYLWLSIATRHPWNQFTRVQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPINLVIGRLFPLIEPQETLPLFPPIQASCLSDASV
Mouse PK1L3 TQDYLWLSVATRHPWNQFTRVQRLSCCMALLLCDMVINIMFWKMGGTTAKRGTEQLGPLAVTLSELLVSIQTSIILFPIHLIFGRLFQLIHPPEALPQLPFIQAAWPPALVC
Human PK1L3 EPLSATMVVEELKETVRFLLRRNTYLLSKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVLQRLKSHLGTLGLTQGHQSCDFLDA
Mouse PK1L3 ESPSLTQVVKELKETVGFLLRRNTQLLSECEPSSCSSCDINKLAKLLSGLIYCHLEDEGCHQQTESHWEDAVSENHYHFCRYLLQLLRRLKAHLEALGATQDHQSCDFSEA
Human PK1L3 ASQLQKLQELLETHILPTEQEPSREVTSFAILSSEEGKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIFISQPVKVVFFTFLYS
Mouse PK1L3 VSQLQNLQELLETQTLRRGPGPCRHSTSFPILSPGEGKKPMSFCLFRWLKCSCWLLLGVISLASAFFITLYSLELDKDQATSWVISMMLSVLQDIFISQPIKVIFLTLLFS
Human PK1L3 LMMSRMPRLNKENEQQTKRILALLAKCSSSVPGSRDKNNPVYVAPAINSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSHQFSEIK
Mouse PK1L3 LMANHMPWLNKDKEQHARRIVALWAKCPWSAPGLRDKNNPIYTAPAMNNLAK-PTRKAWKKQLSKLTGGTLVQILFLTLLMTTVYSAKDSSRFFLHRAIWKRFSHRFSEIK
Human PK1L3 LLQDFYPWANHILLPSLYGDYRG-------------------------------KNAVLEPSHCKCGVQLIFQIPRTKT-YEKVD----------------EGQLAFCDNG
Mouse PK1L3 TVEDFYPWANGTLLPNLYGDYRGFITDGNSFLLGNVLIRQTRIPNDIFFPGSLHKQMKSPPQHQEDRENYGAGWVPPDTNITKVDSIWHYQNQESLGGYPIQGELATYSGG
Human PK1L3 HTCGRP-------KSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIMRGAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKW
Mouse PK1L3 GYVVRLGRNHSAATRVLQHLEQRRWLDHCTKALFVEFTVFNANVNLLCAVTLILESSGVGTFLTSLQLDSLTSLQSSERGFAW-IVSQVVYYLLVCYYAFIQGCRLKRQRL
Human PK1L3 RFFTGKRNILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTG
Mouse PK1L3 AFFTRKRNLLDTSIVLISFSILGLSMQSLSLLHKKMQQYHCDRDRFISFYEALRVNSAVTHLRGFLLLFATVRVWDLLRHHAQLQVINKTLSKAWDEVLGFILIIVVLLSS
Human PK1L3 YAIAFNLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKERKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQ
Mouse PK1L3 YAMTFNLLFGWSISDYQSFFRSIVTVVGLLMGTSKHKEVIALYPILGSLLVLSSIILMGLVIINLFVSAILIAFGKERKACEKEATLTDMLLQKLSSLLGIRLHQNPSEEH
Human PK1L3 AATTAVGSDTEVLDELP
Mouse PK1L3 ADNTGSSNLRERSSKSMSSDL
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