This webinar will be held on zoom. The stucture of the event will be a presentation followed by audience Q&A. Please register to be sent the joining instructions. You can pre-submit questions for the Q&A section when registering.
This webinar is part of the series
Vaccines: Development, Manufacturing and Distribution
The theme discussed in this webinar will be:
Digital Tools in Bioprocess Design and Optimisation
Abstract
Biopharmaceutical manufacturing is challenged by high manufacturing costs and large amount of waste. The complex nature of bioprocesses and measurement unavailability are some of the key challenges of process control. This results in trial-and-error experiments in traditional process development which may be costly and inefficient. Next generation bioprocesses necessitate agility and robustness against variabilities in the end-to-end operation. In that respect, computer modelling solutions can be key for the design of flexible operation and effective process optimisation. In this work, we develop a framework for process space identification using high-fidelity models to obtain a process map relating process inputs and parameters to the main Key Performance Indicators (KPIs). We showcase different methodologies for mapping the process space and assess them based on their accuracy and reliability.
Biography
Dr Maria Papathanasiou
Lecturer (Assistant Professor) in Centre for Process Systems Engineering (CPSE) Dept. of Chemical Engineering
Dr Maria Papathanasiou is a Lecturer (Assistant Professor) at the Department of Chemical Engineering, Imperial College London. She holds a PhD degree in Process Systems Engineering from the Department of Chemical Engineering at Imperial College London and an MSc from the same department. She completed her undergraduate studies at the School of Chemical Engineering, National Technical University of Athens and she conducted her Diploma Thesis in Food Process Engineering at the Technical University of Berlin. Dr Papathanasiou’s research focuses on the development of Process Systems Engineering tools (modelling, optimisation and control) with application to: (a) personalised medicine (from discovery to delivery), (b) biomanufacturing and (c) food systems engineering.
More events in the “Vaccines: Development, Manufacturing and Distribution” Series
- 30 September 14.00 Nanoformulations for Targeted Vaccine Delivery and Stable Storage at Ambient Temperatures presented by Dr. Rongjun Chen
- 7 October 14.00 Quality by digital design and techno-economic modelling of RNA vaccine production for pandemic response presented by Dr. Zoltán Kis
- 21 October 14.00 Forecasting COVID-19 uptake in the UK and monitoring attitudes to COVID-19 vaccines presented by Dr. Alexandre De Figueiredo
- 28 October 14.00 Digital Tools in Bioprocess Design and Optimisation presented by Dr. Maria Papathanasiou
About The Institute for Molecular Science and Engineering
The Institute for Molecular Science and Engineering (IMSE) is one of Imperial College London’s Global Institutes, drawing on the strength of its four faculties to address some of the grand challenges facing the world today. The Institute’s activities are focused on tackling problems where molecular innovation plays an important role.
If you have any questions about accessibility requirements please email Leah Adamson (IMSE Events Officer) on l.adamson@imperial.ac.uk