Cell Biology and Functional Genomics
Read the research publications from the Section of Cell Biology and Functional Genomics
The Section of Cell Biology and Functional Genomics, based on the 3rd floor of the ICTEM Building, Hammersmith Hospital campus, was established to form part of the Department’s and College’s strategic thrust for research into the molecular basis of diabetes.
Part of the recently-established Beta Cell Consortium at Imperial, our research covers a number of areas including, but not limited to, beta cell physiology, the impact of Type 2 diabetes genes on insulin secretion, the role of nutrient regulated protein kinases in maintaining beta cell function and identity, and the role of ‘disallowed’ genes in beta cell function.
Head of Section of Cell biology
Key studies, research groups and collaborations
- Imperial Diabetes Network
- Genetic, epigenetic and nutritional control of pancreatic β-cell identity (MRC)
- β-cell connectivity (Wellcome, Diabetes UK)
- Biomarkers for type 2 diabetes (EU-Rhapsody)
- Incretin receptor signalling (MRC, Diabetes UK)
- Mitochondrial dynamics
- AMPK signalling
Head of Cell Biology and Functional Genomics
Professor Guy Rutter focuses on signal transduction in the pancreatic beta cell in health and disease, chiefly in using functional genomics at the cellular and whole organism level to dissect the role of genes associated with Type 2 diabetes.