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@article{Clar:2017:10.1002/14651858.CD004467.pub3,
author = {Clar, C and Al-Khudairy, L and Loveman, E and Kelly, SAM and Hartley, L and Flowers, N and Germano, R and Frost, G and Rees, K},
doi = {10.1002/14651858.CD004467.pub3},
journal = {Cochrane Database of Systematic Reviews},
title = {Low glycaemic index diets for the prevention of cardiovascular disease},
url = {http://dx.doi.org/10.1002/14651858.CD004467.pub3},
volume = {7},
year = {2017}
}

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TY  - JOUR
AB  - BackgroundThe glycaemic index (GI) is a physiological measure of the ability of a carbohydrate to affect blood glucose. Interest is growing in thisarea for the clinical management of people at risk of, or with, established cardiovascular disease. There is a need to review the currentevidence from randomised controlled trials (RCTs) in this area. This is an update of the original review published in 2008.ObjectivesTo assess the effect of the dietary GI on total mortality, cardiovascular events, and cardiovascular risk factors (blood lipids, bloodpressure) in healthy people or people who have established cardiovascular disease or related risk factors, using all eligible randomisedcontrolled trials.Search methodsWe searched CENTRAL, MEDLINE, Embase and CINAHL in July 2016.We also checked reference lists of relevant articles. Nolanguage restrictions were applied.Selection criteriaWe selected RCTs that assessed the effects of low GI diets compared to diets with a similar composition but a higher GI on cardiovasculardisease and related risk factors. Minimum trial duration was12 weeks. Participants included were healthyadults or those at increased riskof cardiovascular disease, or previously diagnosed with cardiovascular disease. Studies in people with diabetes mellituswere excluded.Data collection and analysisTwo reviewers independently screened and selected studies. Two review authors independently assessed risk of bias, evaluated the overallquality of the evidence using GRADE, and extracted data following theCochrane Handbook for Systematic Reviews of Interventions. Wecontacted trial authors for additional information. Analyses were checked by a second reviewer. Continuous outcomes were synthesizedusing mean differences and adverse events were synthesized narratively.
AU  - Clar,C
AU  - Al-Khudairy,L
AU  - Loveman,E
AU  - Kelly,SAM
AU  - Hartley,L
AU  - Flowers,N
AU  - Germano,R
AU  - Frost,G
AU  - Rees,K
DO  - 10.1002/14651858.CD004467.pub3
PY  - 2017///
SN  - 1469-493X
TI  - Low glycaemic index diets for the prevention of cardiovascular disease
T2  - Cochrane Database of Systematic Reviews
UR  - http://dx.doi.org/10.1002/14651858.CD004467.pub3
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000406831100040&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - http://hdl.handle.net/10044/1/54578
VL  - 7
ER  -

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