Imperial College London

ProfessorPaulFreemont

Faculty of MedicineDepartment of Infectious Disease

Chair in Protein Crystallography
 
 
 
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Contact

 

+44 (0)20 7594 5327p.freemont

 
 
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Location

 

259Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Shiels:2007:10.1371/journal.pcbi.0030138,
author = {Shiels, C and Adams, NM and Islam, SA and Stephens, DA and Freemont, PS},
doi = {10.1371/journal.pcbi.0030138},
journal = {Plos Computational Biology},
pages = {1161--1168},
title = {Quantitative analysis of cell nucleus organisation},
url = {http://dx.doi.org/10.1371/journal.pcbi.0030138},
volume = {3},
year = {2007}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - There are almost 1,300 entries for higher eukaryotes in the Nuclear Protein Database. The proteins' subcellular distribution patterns within interphase nuclei can be complex, ranging from diffuse to punctate or microspeckled, yet they all work together in a coordinated and controlled manner within the three-dimensional confines of the nuclear volume. In this review we describe recent advances in the use of quantitative methods to understand nuclear spatial organisation and discuss some of the practical applications resulting from this work.
AU - Shiels,C
AU - Adams,NM
AU - Islam,SA
AU - Stephens,DA
AU - Freemont,PS
DO - 10.1371/journal.pcbi.0030138
EP - 1168
PY - 2007///
SN - 1553-7358
SP - 1161
TI - Quantitative analysis of cell nucleus organisation
T2 - Plos Computational Biology
UR - http://dx.doi.org/10.1371/journal.pcbi.0030138
UR - http://hdl.handle.net/10044/1/30666
VL - 3
ER -