Imperial College London
Dr Ajay K Gupta

Dr Ajay K Gupta

Faculty of Medicine, National Heart & Lung Institute

Honorary Clinical Senior Lecturer
 
 
 
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Contact

 

+44 (0)20 7594 3437a.k.gupta Website

 
 
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Location

 

ICCH59/61 North Wharf RoadSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Gupta:2010:10.2337/dc09-2208,
author = {Gupta, AK and Dahlof, B and Sever, PS and Poulter, NR},
doi = {10.2337/dc09-2208},
journal = {Diabetes Care},
pages = {1647--1651},
title = {Metabolic Syndrome, Independent of Its Components, Is a Risk Factor for Stroke and Death But Not for Coronary Heart Disease Among Hypertensive Patients in the ASCOT-BPLA},
url = {http://dx.doi.org/10.2337/dc09-2208},
volume = {33},
year = {2010}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - OBJECTIVE — To evaluate whether in hypertensive patients the risk of cardiovascular diseaseis greater in association with the metabolic syndrome (MetS) or the sum of its individualcomponents.RESEARCH DESIGN AND METHODS — Cox regression analysis models were developedto assess the influence of age, sex, ethnicity, and the individual components of MetS on riskassociated with the MetS (using several definitions) of coronary outcomes, stroke, and all-causemortality.RESULTS — MetS was significantly associated with coronary outcomes, stroke, and all-causemortality after adjusting for age, sex, and ethnicity. However, when the model was furtheradjusted for the individual components, MetS was associated with significantly increased risk ofstroke (hazard ratio 1.34 [95% CI 1.07–1.68]) and all-cause mortality (1.35 [1.16–1.58]) butnot coronary outcomes (fatal coronary heart disease plus nonfatal myocardial infarction 1.16[0.95–1.43] and total coronary events 1.06 [0.91–1.24]).CONCLUSIONS — MetS, independent of its individual components, is associated withincreased risk of stroke and all-cause mortality but not coronary outcomes.
AU  - Gupta,AK
AU  - Dahlof,B
AU  - Sever,PS
AU  - Poulter,NR
DO  - 10.2337/dc09-2208
EP  - 1651
PY  - 2010///
SN  - 1935-5548
SP  - 1647
TI  - Metabolic Syndrome, Independent of Its Components, Is a Risk Factor for Stroke and Death But Not for Coronary Heart Disease Among Hypertensive Patients in the ASCOT-BPLA
T2  - Diabetes Care
UR  - http://dx.doi.org/10.2337/dc09-2208
UR  - http://hdl.handle.net/10044/1/29547
VL  - 33
ER  -
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