Imperial College London
Alternate

ProfessorAlisonHolmes

Faculty of Medicine, Department of Infectious Disease

Professor of Infectious Diseases
 
 
 
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Contact

 

+44 (0)20 3313 1283alison.holmes

 
 
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Location

 

8N16Hammersmith HospitalHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Castro:2016:10.1186/s12879-016-1810-x,
author = {Castro, Sanchez EM and Moore, LSP and Husson and Holmes, A},
doi = {10.1186/s12879-016-1810-x},
journal = {BMC Infectious Diseases},
title = {What are the factors driving antimicrobial resistance? Perspectives from a public event in London, England},
url = {http://dx.doi.org/10.1186/s12879-016-1810-x},
volume = {16},
year = {2016}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BackgroundAntimicrobial resistance is driven by multiple factors. Resolving the threat to human and animal health presented by drug-resistant infections remains a societal challenge that demands close collaboration between scientists and citizens. We compared current public views about key contributing factors to antimicrobial resistance with those expressed by experts.MethodsOverarching factors contributing to antimicrobial resistance were identified following a review of literature. The factors were then described in plain language and attached to ballot boxes at a public engagement event organised by a university. Responses to each factor were counted at the end of the event.ResultsFour hundred five responses were received from 3750 visitors (11 % response rate). Nearly half of responses (192/405, 47 · 4 %) considered the misuse/overuse of antibiotics in humans as the main determinant of antimicrobial resistance. The misuse of antibiotics in animal health obtained 16 · 3 % (66/405) responses. However, the lack of quick tests to diagnose infections received 10/405 votes (2 · 47 %), and the lack of effective vaccines received one vote (0 · 25 %).ConclusionsThe majority of responses ascribed the emergence of drug-resistant infections to the misuse of antibiotics in human and animals. Suboptimal dosing, availability of diagnostics and environmental contamination were considered less influential on the development of antimicrobial resistance. The growing recognition of broader multifaceted drivers of drug resistance by experts is not yet echoed in the public mind.
AU  - Castro,Sanchez EM
AU  - Moore,LSP
AU  - Husson
AU  - Holmes,A
DO  - 10.1186/s12879-016-1810-x
PY  - 2016///
SN  - 1471-2334
TI  - What are the factors driving antimicrobial resistance? Perspectives from a public event in London, England
T2  - BMC Infectious Diseases
UR  - http://dx.doi.org/10.1186/s12879-016-1810-x
UR  - http://hdl.handle.net/10044/1/39744
VL  - 16
ER  -
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