Publications
261 results found
Aune D, Chan D, Lau R, et al., 2011, FRUIT AND VEGETABLES AND COLORECTAL CANCER RISK: A NON-LINEAR DOSE-RESPONSE META-ANALYSIS OF COHORT STUDIES, JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH, Vol: 65, Pages: A34-A35, ISSN: 0143-005X
Aune D, Lau R, Chan DSM, et al., 2011, Nonlinear Reduction in Risk for Colorectal Cancer by Fruit and Vegetable Intake Based on Meta-analysis of Prospective Studies, GASTROENTEROLOGY, Vol: 141, Pages: 106-118, ISSN: 0016-5085
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- Citations: 191
Chan DSM, Lau R, Aune D, et al., 2011, Red and processed meat and colorectal cancer incidence: meta-analysis of prospective studies, PLoS ONE, Vol: 6, Pages: 1-11, ISSN: 1932-6203
BackgroundThe evidence that red and processed meat influences colorectal carcinogenesis was judged convincing in the 2007 World Cancer Research Fund/American Institute of Cancer Research report. Since then, ten prospective studies have published new results. Here we update the evidence from prospective studies and explore whether there is a non-linear association of red and processed meats with colorectal cancer risk.Methods and FindingsRelevant prospective studies were identified in PubMed until March 2011. For each study, relative risks and 95% confidence intervals (CI) were extracted and pooled with a random-effects model, weighting for the inverse of the variance, in highest versus lowest intake comparison, and dose-response meta-analyses. Red and processed meats intake was associated with increased colorectal cancer risk. The summary relative risk (RR) of colorectal cancer for the highest versus the lowest intake was 1.22 (95% CI = 1.11−1.34) and the RR for every 100 g/day increase was 1.14 (95% CI = 1.04−1.24). Non-linear dose-response meta-analyses revealed that colorectal cancer risk increases approximately linearly with increasing intake of red and processed meats up to approximately 140 g/day, where the curve approaches its plateau. The associations were similar for colon and rectal cancer risk. When analyzed separately, colorectal cancer risk was related to intake of fresh red meat (RR for 100 g/day increase = 1.17, 95% CI = 1.05−1.31) and processed meat (RR for 50 g/day increase = 1.18, 95% CI = 1.10−1.28). Similar results were observed for colon cancer, but for rectal cancer, no significant associations were observed.ConclusionsHigh intake of red and processed meat is associated with significant increased risk of colorectal, colon and rectal cancers. The overall evidence of prospective studies supports limiting red and processed meat consumption as one of the dietary recommendations for the prevention of colorectal cancer.
Touvier M, Chan DSM, Lau R, et al., 2011, Meta-Analyses of Vitamin D Intake, 25-Hydroxyvitamin D Status, Vitamin D Receptor Polymorphisms, and Colorectal Cancer Risk, CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, Vol: 20, Pages: 1003-1016, ISSN: 1055-9965
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- Citations: 162
Aune D, Deneo-Pellegrini H, Ronco AL, et al., 2011, Dietary folate intake and the risk of 11 types of cancer: a case-control study in Uruguay, ANNALS OF ONCOLOGY, Vol: 22, Pages: 444-451, ISSN: 0923-7534
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- Citations: 51
De Stefani E, Moore M, Aune D, et al., 2011, Mate Consumption and Risk of Cancer: a Multi-site Case-Control Study in Uruguay, ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, Vol: 12, Pages: 1089-1093, ISSN: 1513-7368
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- Citations: 25
Saugstad OD, Aune D, 2011, In Search of the Optimal Oxygen Saturation for Extremely Low Birth Weight Infants: A Systematic Review and Meta-Analysis, NEONATOLOGY, Vol: 100, Pages: 1-8, ISSN: 1661-7800
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- Citations: 60
De Stefani E, Deneo-Pellegrini H, Ronco AL, et al., 2011, Dietary Patterns and Risk of Colorectal Cancer: a Factor Analysis in Uruguay, ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, Vol: 12, Pages: 753-759, ISSN: 1513-7368
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- Citations: 19
Mann J, Aune D, 2010, Can specific fruits and vegetables prevent diabetes?, BMJ-BRITISH MEDICAL JOURNAL, Vol: 341, ISSN: 1756-1833
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- Citations: 1
De Stefani E, Ronco AL, Deneo-Pellegrini H, et al., 2010, Dietary patterns and risk of advanced prostate cancer: a principal component analysis in Uruguay, CANCER CAUSES & CONTROL, Vol: 21, Pages: 1009-1016, ISSN: 0957-5243
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- Citations: 31
Ronco AL, De Stefani E, Aune D, et al., 2010, Nutrient Patterns and Risk of Breast Cancer in Uruguay, ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, Vol: 11, Pages: 519-524, ISSN: 1513-7368
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- Citations: 21
Ronco AL, De Stefani E, Deneo-Pellegrini H, et al., 2010, Dietary Patterns and Risk of Ductal Carcinoma of the Breast: A Factor Analysis in Uruguay, ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, Vol: 11, Pages: 1187-1193, ISSN: 1513-7368
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- Citations: 14
Aune D, Ursin G, Veierod MB, 2009, Meat consumption and the risk of type 2 diabetes: a systematic review and meta-analysis of cohort studies, DIABETOLOGIA, Vol: 52, Pages: 2277-2287, ISSN: 0012-186X
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- Citations: 243
De Stefani E, Boffetta P, Deneo-Pellegrini H, et al., 2009, Meat intake, meat mutagens and risk of lung cancer in Uruguayan men, CANCER CAUSES & CONTROL, Vol: 20, Pages: 1635-1643, ISSN: 0957-5243
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- Citations: 28
Aune D, De Stefani E, Ronco A, et al., 2009, Legume intake and the risk of cancer: a multisite case-control study in Uruguay, CANCER CAUSES & CONTROL, Vol: 20, Pages: 1605-1615, ISSN: 0957-5243
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- Citations: 46
Aune D, Ronco A, Boffetta P, et al., 2009, Meat consumption and cancer risk: a multisite case-control study in Uruguay, Cancer Therapy
De Stefani E, Deneo-Pellegrini H, Boffetta P, et al., 2009, Dietary patterns and risk of cancer: A factor analysis in Uruguay, INTERNATIONAL JOURNAL OF CANCER, Vol: 124, Pages: 1391-1397, ISSN: 0020-7136
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- Citations: 100
De Stefani E, Aune D, Boffetta P, et al., 2009, Salted Meat Consumption and the Risk of Cancer: a Multisite Case-Control Study in Uruguay, ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, Vol: 10, Pages: 853-857, ISSN: 1513-7368
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- Citations: 24
Aune D, De Stefani E, Ronco AL, et al., 2009, Egg Consumption and the Risk of Cancer: a Multisite Case-Control Study in Uruguay, ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, Vol: 10, Pages: 869-875, ISSN: 1513-7368
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- Citations: 29
Aune D, De Stefani E, Ronco A, et al., 2009, Meat Consumption and Cancer Risk: a Case-control Study in Uruguay, ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, Vol: 10, Pages: 429-436, ISSN: 1513-7368
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- Citations: 59
Aune D, De Stefani E, Ronco A, et al., 2009, Fruits, Vegetables and the Risk of Cancer: a Multisite Case-Control Study in Uruguay, ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, Vol: 10, Pages: 419-427, ISSN: 1513-7368
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- Citations: 33
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