Imperial College London
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ProfessorDenisDoorly

Faculty of Engineering, Department of Aeronautics

Professor of Fluid Mechanics
 
 
 
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Contact

 

d.doorly

 
 
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Location

 

313ACity and Guilds BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@inbook{Alemany:2023:10.1007/978-3-031-35302-4_6,
author = {Alemany, I and Ferreira, PF and Nielles-Vallespin, S and Scott, AD and Doorly, DJ},
doi = {10.1007/978-3-031-35302-4_6},
pages = {54--63},
title = {The Effect of Temporal Variations in Myocardial Perfusion on Diffusion Tensor Measurements},
url = {http://dx.doi.org/10.1007/978-3-031-35302-4_6},
year = {2023}
}
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RIS format (EndNote, RefMan)

TY  - CHAP
AB  - The aim of this study is to investigate the impact of velocity fluctuations on the perfusion signal and tensor parameters in diffusion tensor cardiovascular magnetic resonance (DT-CMR) using numerical simulations. A sinusoidal velocity function with increasing amplitude and frequency and a physiological velocity function have been considered. Both velocity functions have been analyzed using two mean inter-capillary velocity distributions with varying levels of dispersion. The results of the perfusion simulations, along with previous diffusion results, have been utilized to analyse the impact of perfusion on the diffusion tensor. The findings indicated that MCSE effectively compensated the rapid velocity changes considered in the study, while PGSE was sensitive to temporal changes in velocity. STEAM was found to be more sensitive to variations in the mean-intercapillary dispersion rather than to temporal velocity fluctuations. These simulation results provide insights regarding the potential of dispersed perfusion velocity fluctuations to affect the DT-CMR signal.
AU  - Alemany,I
AU  - Ferreira,PF
AU  - Nielles-Vallespin,S
AU  - Scott,AD
AU  - Doorly,DJ
DO  - 10.1007/978-3-031-35302-4_6
EP  - 63
PY  - 2023///
SN  - 9783031353017
SP  - 54
TI  - The Effect of Temporal Variations in Myocardial Perfusion on Diffusion Tensor Measurements
UR  - http://dx.doi.org/10.1007/978-3-031-35302-4_6
ER  -
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