Imperial College London
Alternate

Professor David Nutt DM, FRCP, FRCPsych, FSB, FMedSci

Faculty of Medicine, Department of Brain Sciences

The Edmond J Safra Chair in Neuropsychopharmacology
 
 
 
//

Contact

 

d.nutt

 
 
//

Location

 

Burlington Danes BuildingBurlington DanesHammersmith Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Lister:1988:10.1300/J251v07n03_19,
author = {Lister, RG and Nutt, DJ},
doi = {10.1300/J251v07n03_19},
journal = {Adv Alcohol Subst Abuse},
pages = {119--123},
title = {RO 15-4513 and its interaction with ethanol.},
url = {http://dx.doi.org/10.1300/J251v07n03_19},
volume = {7},
year = {1988}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - It has recently been claimed that RO 15-4513 selectively opposes some of the behavioral actions of ethanol. Our studies on the intrinsic effects of this compound have shown it to be proconvulsant and to reduce exploratory behavior in mice. In these respects RO 15-4513 resembles a benzodiazepine receptor partial inverse agonist. Such intrinsic actions may well explain its alcohol-antagonizing properties, and argue against its potential in humans. In addition to partially reversing the effects of ethanol, RO 15-4513 also partially reverses the behavioral effect of a barbiturate and completely reverses the effects of a benzodiazepine.
AU  - Lister,RG
AU  - Nutt,DJ
DO  - 10.1300/J251v07n03_19
EP  - 123
PY  - 1988///
SN  - 0270-3106
SP  - 119
TI  - RO 15-4513 and its interaction with ethanol.
T2  - Adv Alcohol Subst Abuse
UR  - http://dx.doi.org/10.1300/J251v07n03_19
UR  - https://www.ncbi.nlm.nih.gov/pubmed/2851930
VL  - 7
ER  -
Download