Imperial College London
Dr Elaine Burns

DrElaineBurns

Faculty of Medicine, Department of Surgery & Cancer

Honorary Clinical Senior Lecturer
 
 
 
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Contact

 

+44 (0)20 3312 1947e.burns

 
 
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Location

 

Rm. 1029Queen Elizabeth the Queen Mother Wing (QEQM)St Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Sinha:2018:10.1002/bjs5.90,
author = {Sinha, A and Burns, EM and Latchford, A and Clark, SK},
doi = {10.1002/bjs5.90},
journal = {BJS Open},
pages = {452--455},
title = {Risk of desmoid formation after laparoscopic versus open colectomy and ileorectal anastomosis for familial adenomatous polyposis},
url = {http://dx.doi.org/10.1002/bjs5.90},
volume = {2},
year = {2018}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Background: Laparoscopy is used increasingly in prophylactic surgery for patients with familial adenomatous polyposis (FAP) undergoing colectomy with ileorectal anastomosis (IRA). Little is known about the impact of laparoscopy on subsequent desmoid risk. This study documented the risk of desmoid in patients undergoing laparoscopic and open IRA. Methods: This was an observational study of patients with FAP and known germline APC mutation, undergoing IRA at a tertiary referral centre between 1996 and 2016. Patients were retrieved from a prospectively maintained polyposis registry. Data included genotype, family history of desmoid, sex, surgical approach at IRA and postoperative complications. The main outcome was development of either a clinically or radiologically significant desmoid. Results: Some 112 patients (61 female) underwent colectomy and IRA. A laparoscopic approach was used in 69 patients (61·6 per cent). Baseline characteristics did not differ between patients having an open or laparoscopic approach. Median follow-up was 5·8 (i.q.r. 2·4-11·2) years. Patients who underwent laparoscopic IRA had a reduced risk of desmoid formation (3 of 69 (4 per cent) versus 7 of 43 (16 per cent) in the open group; P = 0·043). Discussion: Laparoscopic IRA may reduce risk of subsequent desmoid formation in patients with FAP.
AU  - Sinha,A
AU  - Burns,EM
AU  - Latchford,A
AU  - Clark,SK
DO  - 10.1002/bjs5.90
EP  - 455
PY  - 2018///
SN  - 2474-9842
SP  - 452
TI  - Risk of desmoid formation after laparoscopic versus open colectomy and ileorectal anastomosis for familial adenomatous polyposis
T2  - BJS Open
UR  - http://dx.doi.org/10.1002/bjs5.90
UR  - https://www.ncbi.nlm.nih.gov/pubmed/30511045
UR  - http://hdl.handle.net/10044/1/65054
VL  - 2
ER  -
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